Composition, Acceptability and Efficacy of Fermented and Unfermented Cereal-based Oral Rehydration Solution for Home Management of Diarrhoea in Children

2011 ◽  
Vol 32 (2) ◽  
Author(s):  
HN Ene-Obong ◽  
LA Ejei-Okeke
Keyword(s):  
Oral Rehydration Solution ◽  
Home Management ◽  
Oral Rehydration ◽  
Rehydration Solution

scholarly journals Use of Zinc and Oral Rehydration Solution in Home Management of Diarrhea: Knowledge of Mothers of attending a Tertiary Care Hospital

2019 ◽  
Vol 8 (3) ◽  
pp. 135-140
Author(s):  
Noshina Riaz ◽  
Sidra Tul Muntaha ◽  
Maria Qibtia ◽  
Shugufta Sohail
Keyword(s):  
General Hospital ◽  
Oral Rehydration Solution ◽  
P Value ◽  
Care Hospital ◽  
Home Management ◽  
Oral Rehydration ◽  
Under Five ◽  
Knowledge Variable ◽  
Level Of Knowledge ◽  
Rehydration Solution

Background: Diarrhea is the second leading cause of mortality in children below 5 years of age in Pakistan. Use of Zinc and ORS has been proven in clinical trials to be beneficial in reducing morbidity and mortality. Poor knowledge regarding home management of diarrhea leads to mortality due to severe dehydration. The objective of this study was to assess the level of knowledge of mothers of under five-year-old children regarding, diarrheal home management in Cantonment General Hospital, Rawalpindi. Material and Methods: This was an observational cross-sectional study carried out at Department of Pediatrics, Cantonment General Hospital, Rawalpindi, from 1st August, 2017 to 31st January, 2018. About 400 mothers of under five-year-old children, coming to the outpatient department of the hospital were enrolled in this study. A self-designed structured and validated questionnaire was used to assess the level of knowledge of mothers regarding home management of diarrhea using Oral Rehydration Solution (ORS) and Zinc. Data was analyzed using SPSS version 23 with a p value < 0.05 considered statistically significant. Results: About 91% (n=364) of mothers had awareness regarding use of ORS as a means of diarrheal home management. Regarding level of knowledge variable results were found. A good percentage of mothers had knowledge of the purpose of ORS use (78.3%), administration (60%) and initiation of ORS (68%), but only 20.8% mothers rightly answered the timing of ORS administration. Mothers knowledge about the use of zinc, daily administration and duration of administration (10-14 days) was 38.8% ,20.5% and 17.3% respectively.  Mothers who were more educated especially secondary and above and of the age group 22-31, had better awareness of ORS than others, as P value is less than 0.05. Among mothers who were aware of the use of ORS, only 41.8% of them were also aware of the use of zinc. Conclusion: A high awareness level regarding ORS use in mothers was reflected fairly in terms of purpose, administration and initiation of ORS but the knowledge of mothers regarding use of zinc and timing of ORS administration, in home management of diarrhea is still lacking.

Are oral rehydration solutions optimized for treating diarrhea?

2021 ◽  
pp. 026010602199164
Author(s):  
Samuel N Cheuvront ◽  
Robert W Kenefick ◽  
Laura Luque ◽  
Katherine M Mitchell ◽  
Sadasivan Vidyasagar
Keyword(s):  
Water Absorption ◽  
Intestinal Absorption ◽  
Turning Point ◽  
Oral Rehydration Solution ◽  
Salt Water ◽  
Food Science ◽  
Oral Rehydration ◽  
Rehydration Solutions ◽  
Rehydration Solution ◽  
Stool Volume

Background: A historical turning point occurred in the treatment of diarrhea when it was discovered that glucose could enhance intestinal sodium and water absorption. Adding glucose to salt water (oral rehydration solution, ORS) more efficiently replaced intestinal water and salt losses. Aim: Provide a novel hypothesis to explain why mainstream use of ORS has been strongly recommended, but weakly adopted. Methods: Traditional (absorptive) and novel (secretory) physiological functions of glucose in an ORS were reviewed. Results: Small amounts of glucose can stimulate both intestinal absorption and secretion. Glucose can exacerbate a net secretory state and may aggravate pathogen-induced diarrhea, particularly for pathogens that affect glucose transport. Conclusion: A hypothesis is made to explain why glucose-based ORS does not appreciably reduce diarrheal stool volume and why modern food science initiatives should focus on ORS formulations that replace water and electrolytes while also reducing stool volume and duration of diarrhea.

Oral Rehydration Solution Therapy in the Management of Children with Rotavirus Diarrhea

2009 ◽  
Vol 58 (3) ◽  
pp. 80-87 ◽  
Author(s):  
Germain Nappert ◽  
Jose Miguel Barrios ◽  
Gordon A. Zello ◽  
Jonathan M. Naylor
Keyword(s):  
Oral Rehydration Solution ◽  
Oral Rehydration ◽  
Rehydration Solution ◽  
Rotavirus Diarrhea

scholarly journals 78. TOWARD A SUPER-ORAL REHYDRATION SOLUTION (ORS): ENHANCEMENT OF INTESTINAL WATER ABSORPTION BY A POLY-NUTRIENT SOLUTION

1987 ◽  
Vol 22 (1) ◽  
pp. 109-109
Author(s):  
A Nocerlno ◽  
M Migliavacca ◽  
A Fasano ◽  
C Verqa ◽  
A Ferrara ◽  
...  
Keyword(s):  
Water Absorption ◽  
Nutrient Solution ◽  
Oral Rehydration Solution ◽  
Oral Rehydration ◽  
Rehydration Solution

scholarly journals Oral rehydration solution without bicarbonate.

1984 ◽  
Vol 59 (11) ◽  
pp. 1072-1075 ◽  
Author(s):  
M R Islam ◽  
S M Ahmed
Keyword(s):  
Oral Rehydration Solution ◽  
Oral Rehydration ◽  
Rehydration Solution

Pyruvate-enriched oral rehydration solution improved intestinal absorption of water and sodium during enteral resuscitation in burns

Burns ◽  
2014 ◽  
Vol 40 (4) ◽  
pp. 693-701 ◽  
Author(s):  
Sen Hu ◽  
Wei-wei Liu ◽  
Ying Zhao ◽  
Zhi-long Lin ◽  
Hong-min Luo ◽  
...  
Keyword(s):  
Intestinal Absorption ◽  
Oral Rehydration Solution ◽  
Oral Rehydration ◽  
Rehydration Solution

Clinical Trial of Glucose-Oral Rehydration Solution (ORS), Rice Dextrin-ORS, and Rice Flour-ORS for the Management of Children With Acute Diarrhea and Mild or Moderate Dehydration

PEDIATRICS ◽  
1995 ◽  
Vol 95 (2) ◽  
pp. 191-197
Author(s):  
Susana Molina ◽  
Carolina Vettorazzi ◽  
Janet M. Peerson ◽  
Noel W. Solomons ◽  
Kenneth H. Brown
Keyword(s):  
Clinical Trial ◽  
Treatment Group ◽  
Acute Diarrhea ◽  
Oral Rehydration Solution ◽  
Rice Flour ◽  
Watery Diarrhea ◽  
Hydration Status ◽  
Oral Rehydration ◽  
Acute Watery Diarrhea ◽  
Rehydration Solution

Objective. To assess the effects of glucose (G)-oral rehydration solution (ORS), rice dextrin (RD)-ORS, and rice flour (RF)-ORS on fluid intake, rapidity of rehydration, and stool output of children with acute diarrhea and mild or moderate dehydration. Methods. The study was a randomized, double-masked clinical trial. One hundred forty-six male infants, ages 3 to 36 months, were randomly assigned to one of three treatment groups. Clinical evaluations and fluid balances were conducted every 2 to 4 hours for 48 hours. Principal outcome variables were ORS consumption, recovery of hydration status, and fecal output. Results. The groups were similar at admission with regard to age, nutritional status, history of the current episode, and clinical status. There were no differences in ORS consumption by treatment group during any period of study. During the first 6-hour period, patients in group RF had less stool output (16 ± 14 g/kg/body weight) than those in group G (22 ± 20 g/kg) or RD (21 ± 19 g/kg; P &lt; .05). After 12 hours of hospitalization, there were no differences by treatment group. Recovery of hydration status, changes in serum sodium and potassium, and duration of diarrhea in the hospital were similar in all three groups. Conclusion. There was a 24% to 27% reduction in stool output during the first 6 hours of treatment among children who received RF-ORS compared with those who received G-ORS or RD-ORS, but this effect did not persist after the first 12 hours of therapy. Because this difference was of small magnitude and limited duration, it has minor clinical importance. Thus, we conclude that the three solutions had similar efficacy for children with acute, watery diarrhea and mild or moderate dehydration.

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