F. E. Anstie, ‘The Hypodermic Injection of Remedies’, Practitioner, 1, 1868, 32–41

Author(s):  
Dan Malleck
Keyword(s):  
PEDIATRICS ◽  
1956 ◽  
Vol 18 (1) ◽  
pp. 31-38
Author(s):  
Paul R. Patterson ◽  
Earle L. Lipton ◽  
Klaus R. Unna ◽  
Kurt Glaser

The susceptibility of healthy children to neostigmine by hypodermic injection was studied in controlled experiments on 45 children ranging in age from 1 month to 12 years. Minimum effective doses (MED) of neostigmine were determined by their effect in stimulating salivary and sweat glands, and in increasing gastrointestinal motility. The MED of neostigmine for stimulation of salivation is in all age groups smaller (by 6 to 38 per cent) than the MED increasing gastrointestinal motility. The average MED either for glandular (.025 to .036 mg./kg.) or gastrointestinal (.036 to .045 mg./kg.) activity fails to show significant differences among the various age groups when expressed in terms of body weight. Exceptions were found exclusively in children weighing more than 30 kg. The findings do not support the view that a physiologic vagotonia is present in infants.


BMJ ◽  
1866 ◽  
Vol 1 (273) ◽  
pp. 320-320
Author(s):  
Chas. Hunter
Keyword(s):  

2018 ◽  
Vol 28 (2) ◽  
pp. 38
Author(s):  
SDhanke Prashant ◽  
PUgane Subodh ◽  
RDhumal Prakash ◽  
TQazi Hamza

Sign in / Sign up

Export Citation Format

Share Document