Randy Scholle's reaction (Med. Zh., 1922, no. 5)

The essence of this reaction, which occurs in all infectious diseases of the central nervous system, is as follows: to 1 cubic meter. site, concentrated (1:15) carbolic acid, poured into a small test tube, add 1 kyle of cerebrospinal fluid taken from a patient; if in this case there is an infectious disease of the central nervous system, then, due to the increased content of globulins in the cerebrospinal fluid, a smoky cloud of turbidity is formed in a few seconds throughout the contact of the drop falling to the bottom with the carbolic solution, while the normal liquid of this cloud does not give .

Changing temperatures during progressive paralysis

He says that some man doused him with carbolic acid, his arms and legs are taken away, he has no body. Speech is difficult, the language is braided, the pronunciation of words is not clear. A patient of high stature, severe body build, undermined nutrition. Visible mucous membranes are faint, anemic. Subcutaneous fat is poorly developed.

Pandy's reaction

As is known, the reaction proposed in 1910 by Pandy has long been widely used in neuropathology, the technique of which is very simple: 1 cubic meter is poured into a narrow glass test tube (7 cm long and 1 cm in diameter). sant. saturated solution of carbolic acid (1 hour carbol, crystall. for 15 hours of distillation of water), and a drop of the studied cerebrospinal fluid is introduced into it with a pipette, and the appearance of a blue white cloud throughout the contact of the drop with the reagent indicates a positive result reactions.

Forensic Identification of Air Freshener Components from the Toxicological Samples by GC-MS : a case report

Indoor air fresheners are commonly used to deodorize rooms and cars. A case of air freshener intoxication by oral ingestion was forwarded to the forensic laboratory to determine the components and cause of death. The presumptive tests were conducted for organo-phosphorus and organo-chloro compounds, formaldehyde, carbolic acid, drugs and aromatic compounds. Gas Chromatography–Mass Spectroscopy (GC-MS) was used as a confirmatory test for all these compounds. Presence of toxic substances like dichlorvos (2,2 di-chlorovinyl dimethyl phosphate), phenol, formaldehyde, naphthalene was confirmed in the air freshener that led to the person’s death. Laboratory analysis also confirmed the presence of alprazolam in the viscera as per case history. The methodology used can be utilized as a reference for TLC and GC-MS based analysis of such cases

Lizol in surgery

The author, by means of precise studies, stated that lysol from the point of view of killing bacteria is at least equivalent to carbolic acid, being at the same time much less toxic.

APPLICATION OF ASEPTICS IN SURGERY OF THE ABDOMINAL AND PELVIC CAVITY

The widespread use of the antiseptic or anti-rotting method in the last 20 years, which has yielded brilliant results both in general surgery, and especially in the surgical treatment of diseases of the abdominal and pelvic organs, also has its disadvantages, the main one of which undoubtedly should be considered poisoning when using various anti-rotting medicines. In the literature there is already a rich casuistic material of deadly poisoning when used as an anesthetic, iodoform, carbolic acid, mercuric chloride, etc., etc. antiseptics or antiseptic method of treatment, despite the quick and brilliant success, still left much to be desired and made, during this entire 20-year period, both in laboratory and at the bedside of the patient, to look for means to disinfect the wound, with on the one hand, and not having a harmful effect on patients and those around them, on the other. Carbolic acid was replaced by iodine preparations, iodine preparations with mercuric chloride preparations, mercuric chloride boric acid, copper sulfate, creolin, lysol and many others, some of which have already been abandoned, some are still being tested. The degree of concentration of solutions changed, the time of their contact with the early was limited, and nevertheless, cases of poisoning, which, however, became less common, nevertheless did occur.

Comparative evaluation of different methods of care for the umbilical cord

At the suggestion of the author in the Maternity Department of the Transcaucasian Midwife Institute since 1887, the following method of caring for the umbilical cord has been used: 1) bandaging the umbilical cord with an antiseptic paper or silk cord (preserved after an hour of boiling in an aqueous solution of mercuric chloride 1: 500 in alcohol 1: 500. 1000): 2) washing the remainder of the umbilical cord with a 21/2% solution. carbolic acid, wrapped in absorbent cotton wool (the remainder is then placed on the left side of the abdomen, covered with carbolic acid gauze, with two layers of plain cotton wool and bandaged).

Full delay after increments; postnatal rotting, scraping, wiping with a bannik and tamponation of the uterus. Convalescence

Mrs S., 28 years old. Regulations from 16 years old are incorrect. She has been married since 20 years. Gives birth to the third time. During the second birth, artificial separation after the feverless postpartum course. The third childbirth is difficult, lasted 3 days, the child died in asphyxiation. By the end of 5 days, that is, on February 4, 1889, when the patient was under observation, the cervix was completely closed, the uterus reached the navel, dense, painful with pressure. The general condition is satisfactory, t 38 R. Hot vaginal showers with carbolic acid.

Manufacturing Or Production Defects And Design Defects

There are generally few difficulties in applying the consumer expectation test of s 3(1) of the 1987 Act to manufacturing or production defects. Thus it can be said that: ‘persons generally are clearly entitled to expect that a product conform with the standard of safety common to the items of a same line of products marketed by a particular manufacturer: an individual product which fails to comply with such a standard because it was not produced and marketed as intended will no doubt be considered defective’. Or to put it another way, in the form of an example, ‘no reasonable or “ordinary” consumer expects to find a snail in a bottle of ginger beer’, or, for that matter, carbolic acid in a bottle of lemonade. Accordingly, when the defect is a manufacturing one the consumer expectation test may be straightforward in its application and advantageous.

Carbolic Acid before Joseph Lister: Rail Ties, Sewage, Manure, and the Great Stink

Before Joseph Lister's landmark Lancet publications on the use of carbolic acid wound dressings in 1867, surgeons Jules Lemaire in France and Enrico Bottini in Italy had already used carbolic acid on hundreds of patients to control suppurative wounds. After Friedlieb Runge isolated it from coal tar in 1834, a number of scientists recognized the efficacy of carbolic acid in preventing decay and neutralizing the stench of dead animals and human cadavers. Frederick Calvert, Alexander McDougall, and Angus Smith in Manchester promoted a powdered form of carbolic acid as a deodorizing agent to treat municipal sewage across the United Kingdom, most notably during London's famous “Great Stink” of 1858. Edmond Corne in France introduced his formulation, which Alfred-Armand-Louis-Marie Velpeau, Ferdinand LeBeuf, and Lemaire adapted for clinical use in 1859. Lemaire wrote extensively on carbolic acid and its surgical application in three publications from 1860 to 1862. In 1866, Bottini published his experience of 600 cases where it was used. In 1865, Lister began to use carbolic acid in open fractures after Thomas Anderson, his colleague in agricultural chemistry at the University of Glasgow, told him about its use in Carlisle sewage works. This article traces the rich history of carbolic acid from an unknown compound in coal to the cornerstone of Listerism in late-19th–century operating rooms.