scholarly journals Primary Thyroid Lymphoma

2018 ◽  
Vol 26 (2) ◽  
pp. 122-126
Author(s):  
Manish Gupta ◽  
Ginni Datta ◽  
Naiya Rao ◽  
Eshita Dadwal

Introduction Lymphoma primarily arising from thyroid gland is very rare. Most patients give a history of previous Hashimoto’s thyroiditis and hypothyroidism. Case Report We hereby report one such rare case, who presented with neck swelling and hoarseness. The fine needle aspiration cytology being inconclusive, the patient was taken up for near total thyroidectomy. The histopathology revealed it to be lymphoma, which was further confirmed on immunohistochemistry. The further whole body checkup showed it to be Stage IIE tumor. The patient received chemotherapy for residual mass in neck and is under follow-up for last one year with no recurrence. Discussion The case is being presented here due to its rarity, diagnostic dilemma and to discuss the management protocol for same.

Author(s):  
M. Bharathidasan ◽  
B. Justin William ◽  
Ravi Sundar George Sundar George ◽  
A. Arunprasad ◽  
R. Sivasankar

A two years old Kathiawar stallion was reported with the history of two, pedunculated hard mass medially on the thigh and hock of the right hind limb, progressively increasing for the past two months. Fine needle aspiration cytology revealed fibrosarcoma.The tumour on the medial aspect of the thigh was injected with cisplatin intra-tumorally at a dose rate of 0.3 mg/cm3 of tumour volume and was exposed to ECT. The tumour on the medial aspect of the hock was excised incompletely to preserve skin and subcutaneous tissues around the tumour for wound opposition and treated with intra-tumoral injection of cisplatin followed by ECT. Following electrochemotherapy complete response was noticed onthe 3rd and 4th week for the tumours on the thigh and hock respectively. No recurrence was noticed during the follow-up period of one year revealing ETC with cisplatin as a single treatment and also in combination with surgery is effective for the treatment of fibrosarcoma in equines.


1970 ◽  
Vol 52 (194) ◽  
pp. 831-833 ◽  
Author(s):  
Senjuti Dasgupta ◽  
Sudipta Chakrabarti ◽  
Prakas Kumar Mandal ◽  
Shikha Das

Hashimoto’s thyroiditis has been found to be associated with lymphoma, papillary carcinoma and Hürthle cell neoplasms of thyroid. In contrast, there are only a few reports of co-existence of HT with medullary carcinoma of thyroid. An overall prevalence of medullary carcinoma of only 0.35% has been reported in HT patients. Such a rare combination is being presented here. A 33 year old female presented with history of goiter for one year. Fine needle aspiration cytology of the swelling revealed cytological features suggestive of medullary carcinoma of thyroid. Histopathological examination of total thyroidectomy specimen revealed Hashimoto’s thyroiditis along with medullary carcinoma of thyroid. Although Hashimoto’s thyroiditis can uncommonly coexist with thyroid neoplasm, its association with medullary carcinoma is extremely rare and hence being presented.  Keywords: association, hashimoto’s thyroiditis, histopathology, medullary carcinoma of thyroid.


2013 ◽  
Vol 127 (10) ◽  
pp. 1020-1024 ◽  
Author(s):  
S N Bandyopadhyay ◽  
S Das ◽  
T K Majhi ◽  
G Bandyopadhyay ◽  
D Roy

AbstractIntroduction:Rhinosporidiosis primarily affects the mucous membranes of the nose and nasopharynx. The disseminated form of this chronic fungal disease is extremely rare.Case report:The authors present a case of disseminated rhinosporidiosis in an immunocompetent patient with involvement of the skin, subcutaneous tissue, muscle, bone, penis and urethra, and with a long-standing primary lesion in the nose.Discussion:A late or atypical presentation of rhinosporidiosis may cause diagnostic dilemma. Fine needle aspiration cytology of the tumoural lesions may establish the diagnosis. Histopathology is confirmatory. The subcutaneous masses may be solid or cystic. Ulceroproliferative lesions need to be differentiated from malignancies.Conclusion:This is the first reported case of truly disseminated rhinosporidiosis with simultaneous involvement of multiple anatomically unrelated sites in a single patient. This is also the first reported case of cystic rhinosporidiosis. The possibility and sequelae of spontaneous regression of rhinosporidiosis are also discussed.


2019 ◽  
Vol 12 (11) ◽  
pp. e231305
Author(s):  
Gokul Gopi ◽  
Saurav Sarkar ◽  
Anindya Nayak

A 45-year-old woman presented with a neck swelling since the past 6 years. The swelling was painless but slowly and progressively increasing in size. On examination, a thyroid swelling of size approximately 6×4 cm was seen on the left side. Ultrasonography revealed the size to be 6×5 cm with microcalcifications. Fine needle aspiration cytology revealed the mass to be papillary carcinoma. She was planned for total thyroidectomy with central compartment clearance. Preoperative assessment including thyroid hormone profile was normal and the patient was taken for surgery after proper anaesthesia clearance. During the surgery, it was found that there was a branching of the left recurrent laryngeal nerve. The branching was confirmed with nerve monitor and careful dissection was done to prevent injuries. The surgery was completed successfully without any nerve damage and the postoperative period was uneventful. Follow-up assessments revealed no signs of nerve injury like hoarseness of voice. Possibility of abnormal branches and duplication of nerves though uncommon should not be underestimated and extra vigilance and caution must be exercised when operating near a nerve, even by an experienced surgeon familiar with the local anatomy. Any doubts arising during the surgery must be clarified immediately, and nerve monitors should be used to check suspected branching and duplications before proceeding further.


Rare Tumors ◽  
2010 ◽  
Vol 2 (1) ◽  
pp. 16-19 ◽  
Author(s):  
Ayman Elnemr ◽  
Yutaka Yonemura ◽  
Masaya Shinbo ◽  
Eisei Nishino

Mullerian tumors are extremely rare malignancies in the retroperitoneum. We report a case of a 46-year old woman who presented with an eight year history of lower abdominal mass. Ultrasonography (US) and computed tomography (CT) demonstrated a 15×10 cm cystic mass in the left lower retroperitoneum. As serial percutaneous needle aspiration cytology was negative for malignancy, she was observed for seven years. Eleven months ago, the mass was excised. The histopathology was reported as mucinous adenocarcinoma of the retroperitoneum. Six cycles of intraperitoneal (IP) chemotherapy was administered during the last six months after diagnosis of recurrence by aspiration cytology and high serum tumor markers (CEA, CA19-9). A few days ago, positron emission tomographic (PET) scanning showed evidence of local recurrence and single vertebral metastasis, so she was admitted again for systemic chemotherapy. Meticulous revision of additional sections of the tumor revealed papillary, serous, mucinous, and endometrioid subtypes of the mullerian adenocarcinoma. To our knowledge, there has been no similar case described in the literature.


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