scholarly journals Hashimoto's Thyroiditis and Medullary Carcinoma of Thyroid

1970 ◽  
Vol 52 (194) ◽  
pp. 831-833 ◽  
Author(s):  
Senjuti Dasgupta ◽  
Sudipta Chakrabarti ◽  
Prakas Kumar Mandal ◽  
Shikha Das
Keyword(s):  
Hashimoto’S Thyroiditis ◽  
Histopathological Examination ◽  
Medullary Carcinoma ◽  
Needle Aspiration ◽  
Hashimoto's Thyroiditis ◽  
Aspiration Cytology ◽  
History Of ◽  
Cytological Features ◽  
Needle Aspiration Cytology ◽  
One Year

Hashimoto’s thyroiditis has been found to be associated with lymphoma, papillary carcinoma and Hürthle cell neoplasms of thyroid. In contrast, there are only a few reports of co-existence of HT with medullary carcinoma of thyroid. An overall prevalence of medullary carcinoma of only 0.35% has been reported in HT patients. Such a rare combination is being presented here. A 33 year old female presented with history of goiter for one year. Fine needle aspiration cytology of the swelling revealed cytological features suggestive of medullary carcinoma of thyroid. Histopathological examination of total thyroidectomy specimen revealed Hashimoto’s thyroiditis along with medullary carcinoma of thyroid. Although Hashimoto’s thyroiditis can uncommonly coexist with thyroid neoplasm, its association with medullary carcinoma is extremely rare and hence being presented.  Keywords: association, hashimoto’s thyroiditis, histopathology, medullary carcinoma of thyroid.

scholarly journals Hyalinizing Granuloma: An Unusual Case of a Pulmonary Mass

2010 ◽  
Vol 2010 ◽  
pp. 1-3 ◽  
Author(s):  
Viviane Brandão ◽  
Edson Marchiori ◽  
Gláucia Zanetti ◽  
Guilherme Abdalla ◽  
Nina Ventura ◽  
...  
Keyword(s):  
Unusual Case ◽  
Histopathological Examination ◽  
Laboratory Data ◽  
Previous Treatment ◽  
Needle Aspiration ◽  
Open Lung Biopsy ◽  
Aspiration Cytology ◽  
Ct Guided ◽  
History Of ◽  
Needle Aspiration Cytology

We describe the case of pulmonary hyalinizing granuloma in a 34-year-old asymptomatic man who presented with a pulmonary nodule apparent by chest radiography and computed tomography (CT). He had a history of previous treatment for tuberculosis. His laboratory data were normal. Bronchoscopy and CT-guided percutaneous transthoracic fine needle aspiration cytology were inconclusive. The diagnosis was revealed after the histopathological examination of an open lung biopsy.

scholarly journals Cytomorphological Aspects of Hashimoto's Thyroiditis: Our Experience at a Tertiary Center

2014 ◽  
Vol 7 ◽  
pp. CPath.S13580 ◽  
Author(s):  
Monika Rathi ◽  
Faiyaz Ahmad ◽  
Satish Kumar Budania ◽  
Seema Awasthi ◽  
Ashutosh Kumar ◽  
...  
Keyword(s):  
Fine Needle Aspiration ◽  
Hashimoto’S Thyroiditis ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Hashimoto's Thyroiditis ◽  
Thyroid Function Tests ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Tertiary Center ◽  
Needle Aspiration Cytology

Introduction Hashimoto's thyroiditis is the most common form of acquired hypothyroidism. Fine needle aspiration cytology is one important tool in diagnosing Hashimoto's thyroditis, along with clinical, biochemical, immunological and ultrasonographical modalities. The present study examines cytological aspects of Hashimoto's thyroiditis along with their correlation with clinical, biochemical and immunological findings, whenever available. Materials and Methods This is a retrospective study of 50 cases of Hashimoto's thyroiditis. Cytological findings were reviewed and correlated with clinical, biochemical and immunological findings whenever available. Results The majority of the patients were middle-aged females, with a female to male ratio of 6.14:1. Most patients presented with diffuse thyromegaly (68%) and/or hypothyroidism (56.09%). The antibody profile was available in 22% of patients. Of these, anti-thyroid peroxidase antibodies were raised in 81.81% of patients and anti-thyroglobulin antibodies were raised in 63.63% of patients. In the present study, high lymphoid to epithelial cell ratio was seen in 78% of cases, and 74% of cases showed Hurthle cell change. Follicular atypia was seen in 36% of cases. Lymphoid follicle formation was seen in seen in 54% of cases. Follicular cell infiltration by lymphocytes, eosinophils and neutrophils was seen in 72%, 48% and 26% of cases, respectively. Plasma cells were seen in 18% of cases. Conclusion Thyroid function tests and immunological tests cannot diagnose all cases of Hashimoto's thyroiditis. Fine needle aspiration cytology continues to be a diagnostic tool of significance in diagnosing Hashimoto's thyroiditis. The presence of inflammatory cells, particularly lymphocytes and eosinophils, was detected in a significant proportion of cases.

scholarly journals Primary Mucosa-Associated Lymphoid Tissue Lymphoma of Thyroid with the Serial Ultrasound Findings

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Eon Ju Jeon ◽  
Ho Sang Shon ◽  
Eui Dal Jung
Keyword(s):  
Natural History ◽  
Hashimoto’S Thyroiditis ◽  
Lymphoid Tissue ◽  
Marginal Zone ◽  
Needle Aspiration ◽  
Marginal Zone Lymphoma ◽  
Hashimoto's Thyroiditis ◽  
Extranodal Marginal Zone Lymphoma ◽  
History Of ◽  
Needle Aspiration Cytology

Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT) of the thyroid gland is uncommon. Even though its natural history is not well defined, it is known to be indolent course. We present a case of primary MALT thyroid lymphoma with the serial sonographic findings in the patient presenting as the focal nodule. A 45-year-old woman visited our hospital for neck examination. Initially, fine-needle aspiration cytology in the focal hypoechoic lesion in the left thyroid lobe on ultrasound sonography was performed and consistent with Hashimoto’s thyroiditis. However, the results of serial ultrasounds and core-needle biopsy revealed an extranodal marginal zone lymphoma of MALT on 4-year follow-up. Patients with a focal hypoechoic nodule with linear echogenic strands and segmental pattern in the background of Hashimoto’s thyroiditis on ultrasonography should undergo careful surveillance for malignancy. Serial sonographic features in this case are meaningful in the understanding of the natural history of the extranodal marginal zone lymphoma of MALT of the thyroid.

scholarly journals Primary Thyroid Lymphoma

2018 ◽  
Vol 26 (2) ◽  
pp. 122-126
Author(s):  
Manish Gupta ◽  
Ginni Datta ◽  
Naiya Rao ◽  
Eshita Dadwal
Keyword(s):  
Needle Aspiration ◽  
Whole Body ◽  
Thyroid Lymphoma ◽  
Aspiration Cytology ◽  
Diagnostic Dilemma ◽  
Management Protocol ◽  
History Of ◽  
Needle Aspiration Cytology ◽  
One Year

Introduction Lymphoma primarily arising from thyroid gland is very rare. Most patients give a history of previous Hashimoto’s thyroiditis and hypothyroidism. Case Report We hereby report one such rare case, who presented with neck swelling and hoarseness. The fine needle aspiration cytology being inconclusive, the patient was taken up for near total thyroidectomy. The histopathology revealed it to be lymphoma, which was further confirmed on immunohistochemistry. The further whole body checkup showed it to be Stage IIE tumor. The patient received chemotherapy for residual mass in neck and is under follow-up for last one year with no recurrence. Discussion The case is being presented here due to its rarity, diagnostic dilemma and to discuss the management protocol for same.

scholarly journals Is there any association between Hashimoto’s thyroiditis and thyroid cancer? A retrospective data analysis

2015 ◽  
Vol 48 (3) ◽  
pp. 148-153 ◽  
Author(s):  
Daysi Maria de Alcântara-Jones ◽  
Tania Freitas de Alcântara-Nunes ◽  
Bruno de Oliveira Rocha ◽  
Rafael Daltro de Oliveira ◽  
Allan Chastinet Pitangueira Santana ◽  
...  
Keyword(s):  
Hashimoto’S Thyroiditis ◽  
Malignant Disease ◽  
Needle Aspiration ◽  
Hashimoto's Thyroiditis ◽  
Papillary Thyroid ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Retrospective Data Analysis ◽  
Needle Aspiration Cytology ◽  
Histopathological Results

Abstract Objective: To evaluate the association between Hashimoto's thyroiditis (HT) and papillary thyroid carcinoma (PTC). Materials and Methods: The patients were evaluated by ultrasonography-guided fine needle aspiration cytology. Typical cytopathological aspects and/or classical histopathological findings were taken into consideration in the diagnosis of HT, and only histopathological results were considered in the diagnosis of PTC. Results: Among 1,049 patients with multi- or uninodular goiter (903 women and 146 men), 173 (16.5%) had cytopathological features of thyroiditis. Thirty-three (67.4%) out of the 49 operated patients had PTC, 9 (27.3%) of them with histopathological features of HT. Five (31.3%) out of the 16 patients with non-malignant disease also had HT. In the groups with HT, PTC, and PCT+HT, the female prevalence rate was 100%, 91.6%, and 77.8%, respectively. Mean age was 41.5, 43.3, and 48.5 years, respectively. No association was observed between the two diseases in the present study where HT occurred in 31.1% of the benign cases and in 27.3% of malignant cases (p = 0.8). Conclusion: In spite of the absence of association between HT and PCT, the possibility of malignancy in HT should always be considered because of the coexistence of the two diseases already reported in the literature.

scholarly journals Diagnostic relevance of fine needle aspiration cytology in nodular thyroid lesions

2012 ◽  
Vol 69 (7) ◽  
pp. 555-561 ◽  
Author(s):  
Slavica Knezevic-Usaj ◽  
Zivka Eri ◽  
Milana Panjkovic ◽  
Istvan Klem ◽  
Tomislav Petrovic ◽  
...  
Keyword(s):  
Diagnostic Accuracy ◽  
Thyroid Nodule ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Histopathological Examination ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology ◽  
One Year

Background/Aim. Fine needle aspiration cytology (FNAC) of the thyroid gland has been used as an initial investigative procedure of thyroid nodule(s) in the Department of Pathology at the Institute of Oncology of Vojvodina for more than 20 years. This procedure is rapid, inexpensive and technologically simple, yet it has found only limited, albeit increasing acceptance in medical practice in Serbia. The aim of the study was to evaluate our FNAC findings by correlating cytological results with histological diagnosis and to define the sensitivity, diagnostic accuracy and positive predictive value of FNAC. Methods. A total of 266 patients with thyroid swellings were aspirated in one year investigated period at our Institute out of whom 69 underwent surgery between May 2008 and May 2009. The cytological results correlated with clinical features, ultrasound investigations (US) and subsequent histopathological examination of the resected tissue. Results. By the use of cytology we found out thyroid carcinoma in 10 patients, and by histopathological examination in 12. We obtained 83% sensitivity, 100% specificity and 97% of diagnostic accuracy of FNAC. Conclusion. The obtained results confirm the importance of FNAC in preoperative assesment of thyroid nodule.

scholarly journals Cysticercosis: Hooked by a Hooklet on Fine Needle Aspiration Cytology—A Case Report

2013 ◽  
Vol 2013 ◽  
pp. 1-2 ◽  
Author(s):  
Manav Sawhney ◽  
Shubhra Agarwal
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Histopathological Examination ◽  
Bladder Wall ◽  
Clinical Manifestations ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Muscle Involvement ◽  
Fine Needle ◽  
Needle Aspiration Cytology

Cysticercosis is a systemic parasitic disease caused by the larval form of cestodeT. solium. It has a worldwide distribution and is potentially harmful with variable clinical manifestations. The patient most commonly presents with subcutaneous and muscle involvement in the form of nodular lesions. The other most commonly involved sites include eye, brain, bladder wall, and heart. Cysticercosis can be diagnosed on serology, and radiologically but confirmatory diagnosis is based on histopathological examination of the involved tissue biopsy specimen. Fine needle aspiration cytology is a useful low-cost outpatient procedure tool for preoperative diagnosis of cysticercosis and is absolutely essential for diagnosis of the parasitic lesions in a peripheral hospital, one like ours.

Sign in / Sign up

Export Citation Format

Share Document