Non-Hodgkin's Lymphoma of Thyroid Synchronously with Squamous cell carcinoma base of Tongue: A Rare coincidence and Treatment Strategy

ABSTRACT The occurrence of two malignant lesions synchronously of different histology at same anatomical region of the patient is a rare presentation. Coexistence of squamous cell carcinoma and malignant lymphoma of head and neck region synchronously is uncommon. Here is a report of case of 65 years old female patient who presented with a mass in right side of neck and in midline of neck of 2 months duration. After thorough work up, the patient was diagnosed as having squamous cell carcinoma of right side base of tongue and non-Hodgkin's lymphoma (NHL) of thyroid. The patient was treated with radiotherapy and chemotherapy. How to cite this article Kaur P, Khurana A, Chauhan AK, Singh G, Kataria SP. Non-Hodgkin's Lymphoma of Thyroid Synchronously with Squamous Cell Carcinoma Base of Tongue: A Rare Coincidence and Treatment Strategy. Int J Head Neck Surg 2014;5(3):155-157.

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Head and neck squamous cell cancer associated with lymphoproliferative malignancies is aggressive

The Journal of Laryngology & Otology ◽

10.1017/s0022215120000729 ◽

2020 ◽

Vol 134 (5) ◽

pp. 460-462

Author(s):

L Li ◽

L Hamilton ◽

J Montgomery ◽

M Stewart

Keyword(s):

Squamous Cell Carcinoma ◽

Chronic Lymphocytic Leukaemia ◽

Cell Carcinoma ◽

Head And Neck ◽

Squamous Cell ◽

Hodgkin’S Lymphoma ◽

Lymphocytic Leukaemia ◽

Hodgkin's Lymphoma ◽

Non Hodgkin’S Lymphoma ◽

Non Hodgkin's Lymphoma

AbstractBackgroundPatients with non-Hodgkin's lymphoma and chronic lymphocytic leukaemia are at an elevated risk of further malignancy. Head and neck squamous cell carcinoma often presents with cervical lymph node metastasis, and can pose a diagnostic challenge in patients with non-Hodgkin's lymphoma or chronic lymphocytic leukaemia who may have pre-existing palpable neck nodes.MethodsA retrospective case review of a health board was conducted to identify patients with head and neck squamous cell carcinoma with a previous diagnosis of non-Hodgkin's lymphoma or chronic lymphocytic leukaemia.ResultsFour patients with head and neck squamous cell carcinoma that developed after non-Hodgkin's lymphoma or chronic lymphocytic leukaemia were identified. Two patients had a background of non-Hodgkin's lymphoma treated with chemotherapy. The remaining two patients had a background of chronic lymphocytic leukaemia under active surveillance. Three out of the four patients died within 30 months of diagnosis.ConclusionHead and neck squamous cell carcinoma following non-Hodgkin's lymphoma or chronic lymphocytic leukaemia is aggressive. A heightened clinical suspicion is essential to facilitate early diagnosis and treatment of head and neck squamous cell carcinoma in patients with dual pathology.

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Coexistence of laryngeal squamous cell carcinoma and non-Hodgkin's lymphoma with nasopharyngeal involvement

The Journal of Laryngology & Otology ◽

10.1017/s0022215105000782 ◽

2005 ◽

Vol 120 (2) ◽

pp. 1-4 ◽

Cited By ~ 9

Author(s):

Mesut Sabrı Tezer ◽

Ümit Tuncel ◽

Samet Özlügedik ◽

Murat Uzun ◽

Sezer Kulaçoğlu ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Squamous Cell ◽

Hodgkin’S Lymphoma ◽

Laryngeal Squamous Cell Carcinoma ◽

Neck Region ◽

Hodgkin's Lymphoma ◽

Non Hodgkin’S Lymphoma ◽

Non Hodgkin's Lymphoma ◽

Second Primaries

Laryngeal squamous cell carcinoma (SCC) is one of the most frequent malignancies in the head and neck region. The risk of multiple malignancies is reported as 2–11 per cent and most of the second primaries are SCCs. Lymphogenic tumours as second primaries are extremely rare. In this paper, we report a case of laryngeal SCC with synchronous non-Hodgkin's lymphoma and review the literature on the clinical and histopathological aspects of these malignancies.

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