Glandular Odontogenic Cyst Mimicker: A Novel Entity

2016 ◽  
Vol 6 (2) ◽  
pp. 145-148
Author(s):  
Kehkashan E Azmi
Keyword(s):  
Mucoepidermoid Carcinoma ◽  
Dentigerous Cyst ◽  
Odontogenic Cyst ◽  
Biological Behavior ◽  
Low Grade ◽  
Glandular Odontogenic Cyst ◽  
Transformation Potential ◽  
Collaborative Efforts ◽  
Lateral Periodontal Cyst ◽  
Maxillary Region

ABSTRACT Glandular odontogenic cyst (GOC) is an uncommon developmental odontogenic cyst of jaws with a frequency of approximately 0.2%. Because of its aggressive biological behavior including its malignant transformation potential, recently collaborative efforts by few researchers have laid down certain histopathological criteria segregating it from its mimickers which include dentigerous cyst, lateral periodontal cyst (LPC), or botryoid cyst, radicular cyst, and central low-grade mucoepidermoid carcinoma. Therefore, cautious histopathological evaluation is necessary of GOC mimickers in order to prevent its overdiagnosis. Here, we present a case of GOC mimicker in a 12-year-old male patient in left maxillary region. How to cite this article Azmi KE, Patel S, Pathak J, Swain N. Glandular Odontogenic Cyst Mimicker: A Novel Entity. J Contemp Dent 2016;6(2):145-148.

Unique case of glandular odontogenic cyst showing mucoepidermoid carcinoma-like islands in cystic wall

2021 ◽  
Vol 14 (2) ◽  
pp. e239362
Author(s):  
Harpreet Kaur ◽  
Deepika Mishra ◽  
Rahul Yadav
Keyword(s):  
Mucoepidermoid Carcinoma ◽  
Final Diagnosis ◽  
Odontogenic Cyst ◽  
Odontogenic Cysts ◽  
Low Grade ◽  
Male Predominance ◽  
Glandular Odontogenic Cyst ◽  
Jaw Cyst ◽  
Intermediate Cells ◽  
Anterior Mandible

Glandular odontogenic cyst (GOC) is a very rare jaw cyst accounting for 0.2% of all odontogenic cysts. It presents usually in adults with a slight male predominance. It shows radiological, histopathological and even immunohistochemical overlap with low grade intraosseous mucoepidermoid carcinoma (MEC) but their distinction is crucial. A 57-year-old woman with bilocular radiolucency in the anterior mandible crossing the midline is described here. Microscopy features were consistent with glandular odontogenic cyst but multiple MEC-like islands were seen in the capsule, creating a diagnostic head trip with low grade intraosseous MEC. However, the absence of cellular atypia and epidermoid and intermediate cells led to a final diagnosis of GOC, with close follow-up of the patient recommended. This rare finding shows the relation between GOC and MEC or the origin of MEC from GOC.

scholarly journals Glandular Odontogenic Cyst: Review of Literature and Report of a New Case with Cytokeratin-19 Expression

2014 ◽  
Vol 8 (1) ◽  
pp. 1-12 ◽  
Author(s):  
Marco Mascitti ◽  
Andrea Santarelli ◽  
Antonio Sabatucci ◽  
Maurizio Procaccini ◽  
Lorenzo Lo Muzio ◽  
...  
Keyword(s):  
Mucoepidermoid Carcinoma ◽  
Squamous Epithelium ◽  
Odontogenic Cyst ◽  
Cytokeratin 19 ◽  
Review Of Literature ◽  
Distinct Entity ◽  
Radiographic Findings ◽  
Glandular Odontogenic Cyst ◽  
Stratified Squamous Epithelium ◽  
Central Mucoepidermoid Carcinoma

The glandular odontogenic cyst (GOC) was a rare jawbone cyst described in 1988 as a distinct entity. This lesion can involve either jaw, and the anterior region of the mandible was the most commonly affected area. Clinical and radiographic findings were not specific, and the diagnosis of GOC can be extremely difficult due to the rarity of this lesion. The cyst presented a wall constituted by fibrous connective tissue and was lined by a non-keratinized stratified squamous epithelium of variable thickness. Large areas of the lining epithelium presented cylinder cells, sometimes ciliated. A variable amount of mucina was occasionally noted. Due to the strong similarities, this cyst can be easily misdiag-nosed as a central mucoepidermoid carcinoma (CMEC). Immunohistochemistry may be an aid in diagnosis; in fact has been demonstrated that there were differences in the expression of cytokeratins (CK) in GOC and CMEC. In this study, we reported a new case of GOC in a 38 year female patient. In addition, we carried out a review of 110 previous cases reported in literature.

Glandular Odontogenic Cyst Presenting as a Dentigerous Cyst: A Case Report

2006 ◽  
Vol 64 (4) ◽  
pp. 731-733 ◽  
Author(s):  
Oğuzcan Kasaboğlu ◽  
Zehra Başal ◽  
Alp Usubütün
Keyword(s):  
Case Report ◽  
Dentigerous Cyst ◽  
Odontogenic Cyst ◽  
Glandular Odontogenic Cyst

Central mucoepidermoid carcinoma arising from glandular odontogenic cyst confirmed by analysis of MAML2 rearrangement: A case report

2017 ◽  
Vol 68 (1) ◽  
pp. 31-35 ◽  
Author(s):  
Atsuhiro Nagasaki ◽  
Ikuko Ogawa ◽  
Yukiko Sato ◽  
Kengo Takeuchi ◽  
Masae Kitagawa ◽  
...  
Keyword(s):  
Case Report ◽  
Mucoepidermoid Carcinoma ◽  
Odontogenic Cyst ◽  
Glandular Odontogenic Cyst ◽  
Central Mucoepidermoid Carcinoma

Use of molecular diagnostics to distinguish glandular odontogenic cyst and mucoepidermoid carcinoma

2015 ◽  
Vol 44 ◽  
pp. e183
Author(s):  
A. Abdullakutty ◽  
A.W. Barrett ◽  
D.M. Coombes ◽  
B.S. Bisase ◽  
M. Faulkner ◽  
...  
Keyword(s):  
Molecular Diagnostics ◽  
Mucoepidermoid Carcinoma ◽  
Odontogenic Cyst ◽  
Glandular Odontogenic Cyst
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