scholarly journals Red Ginseng Acidic Polysaccharides Promote the Expression of Acne-Related Inflammatory Biomarkers in Lipopolysaccharide-Treated Sebocytes and Outer Root Sheath Cells and Cutibacterium acnes-Injected Mice

2021 ◽  
Vol 33 (5) ◽  
pp. 409
Author(s):  
Hyun Ji Lee ◽  
Mi Hee Kwack ◽  
Weon Ju Lee
Keyword(s):  
Inflammatory Biomarkers ◽  
Red Ginseng ◽  
Outer Root Sheath ◽  
Root Sheath ◽  
Cutibacterium Acnes ◽  
Acidic Polysaccharides ◽  
Outer Root Sheath Cells ◽  
Sheath Cells

scholarly journals Effect of Red Ginseng Oil on Cultured Sebocytes and Outer Root Sheath Cells after Treatment with Lipopolysaccharide

2021 ◽  
Vol 33 (3) ◽  
pp. 245
Author(s):  
Han-Jin Jung ◽  
Seon Hwa Lee ◽  
Mi Hee Kwack ◽  
Weon Ju Lee
Keyword(s):  
Red Ginseng ◽  
Outer Root Sheath ◽  
Root Sheath ◽  
Outer Root Sheath Cells ◽  
Sheath Cells

scholarly journals Red Ginseng Water Extract Aggravates Inflammation in Sebocytes and Outer Root Sheath Cells After Treatment With Lipopolysaccharide and Mice With Cutibacterium Acnes-induced Inflammatory Nodules

2021 ◽  
Author(s):  
Mi Hee Kwack ◽  
Weon Ju Lee
Keyword(s):  
Protein Expression ◽  
Acne Vulgaris ◽  
Water Extract ◽  
Red Ginseng ◽  
Outer Root Sheath ◽  
Root Sheath ◽  
Cutibacterium Acnes ◽  
Mrna And Protein Expression ◽  
White Ginseng ◽  
Outer Root Sheath Cells

Abstract Ginseng has been known in Korea as a health-supportive herbal medicine from time immemorial. Red ginseng is one of processed ginseng that is produced from white ginseng through steaming and drying. Many protective functions of red ginseng have been reported from various groups in many diseases. In this study, we first investigated whether red ginseng water extract (RG) aggravates inflammation in human sebocytes and outer root sheath (ORS) cells after treatment with lipopolysaccharide (LPS) and mice with Cutibacterium (C.) acnes strain (ATCC 1182)-induced inflammatory nodules. Sebocytes and ORS cells were isolated and cultured from the human scalp. The RG augmented LPS mediated inflammation by increased the mRNA and protein expression of inflammatory cytokines in sebocytes and ORS cells. In addition, RG also showed the increased protein expression of p-NFκB, p-c-jun and p-JNK in the LPS-treated sebocytes and ORS cells. Furthermore, RG upregulated the LPS-induced production of sebum in sebocytes. In addition, RG inhibited improvement of inflammatory nodules and showed the increased expression of inflammatory biomarkers in inflammatory nodules of Cutibacterium acnes injected mice. Collectively, our data strongly suggest that RG is one of the aggravating factors of acne vulgaris. It would be better to stop taking RG in patients with inflammatory acne.

Effect of Minoxidil Sulfate on the Growth of Human Anagen Hair Follicles Grown in Collagen Gels, and on the Colony Growth of Human Cultured Outer Root Sheath Cells in vitro.

1992 ◽  
Vol 54 (4) ◽  
pp. 727-732 ◽  
Author(s):  
Naoyuki UCHIDA ◽  
Takesi FUJIE ◽  
Seiji ARASE ◽  
Yosiroh NINOMIYA ◽  
Hideki NAKANISI ◽  
...  
Keyword(s):  
Colony Growth ◽  
Hair Follicles ◽  
Collagen Gels ◽  
Outer Root Sheath ◽  
Root Sheath ◽  
Anagen Hair ◽  
Outer Root Sheath Cells ◽  
Sheath Cells

Knockdown of HIF-1α inhibits the proliferation and migration of outer root sheath cells exposed to hypoxia in vitro: An involvement of Shh pathway

Life Sciences ◽  
2017 ◽  
Vol 191 ◽  
pp. 82-89 ◽  
Author(s):  
Haihua Zhang ◽  
Weixiao Nan ◽  
Xingchao Song ◽  
Shiyong Wang ◽  
Huazhe Si ◽  
...  
Keyword(s):  
Outer Root Sheath ◽  
Shh Pathway ◽  
Root Sheath ◽  
And Migration ◽  
Outer Root Sheath Cells ◽  
Proliferation And Migration ◽  
Sheath Cells

scholarly journals The Structure Anchoring Underfur in Outer Root Sheath Cells of Telogen Mink Hair Follicles

1991 ◽  
Vol 62 (8) ◽  
pp. 714-716
Author(s):  
Fumio NAKAMURA ◽  
Kunihiro KAJI ◽  
Shigeharu FUKUNAGA ◽  
Kaoru KOHNO ◽  
Keiji KONDO
Keyword(s):  
Hair Follicles ◽  
Outer Root Sheath ◽  
Root Sheath ◽  
Outer Root Sheath Cells ◽  
Sheath Cells
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