scholarly journals The importance of specific IgE antibodies in epidemiology of allergic rhinitis and asthma – the Epidemiology of Allergic Diseases in Poland (ECAP) survey: part one. Influence of allergy risk factors on concentration of specific IgE antibodies in serum

2018 ◽  
Vol 35 (5) ◽  
pp. 520-526
Author(s):  
Andrzej Namysłowski ◽  
Bolesław K. Samoliński ◽  
Agnieszka Lipiec ◽  
Wojciech Zieliński ◽  
Adam J. Sybilski ◽  
...  
2011 ◽  
Vol 68 (8) ◽  
pp. 690-695 ◽  
Author(s):  
Nevenka Ilic ◽  
Vesna Velickovic ◽  
Dragoljub Djokic ◽  
Nebojsa Rankovic ◽  
Gordana Kostic ◽  
...  

Background/Aim. Atopic diseases such as atopic dermatitis, allergic rhinitis and asthma have had increased prevalence during the past decade and nowadays occur in every third child in developed countries. The aim of the study was to determine frequency and type of atopic diseases at the age of two, as well as the importance the total IgE antibodies concentrations have in diagnosis and prognosis of the disease. Methods. The study involved 175 children up to two years of age. Allergy-like symptoms were found after surveying their parents and pediatric medical records. Using the fluorescence immunossay (FIA) method, total IgE antibodies concentrations and specific IgE antibodies (Phadiatop infant) were determined on an Immunocap 100 Dyagnostic System. Results. One or more allergy-like symptoms accounted for 57.7% of findings in children under the age of two, whilst in 19.4% the existence of IgE-related allergic diseases was found. Atopic diseases usually have clinical manifestations of atopic dermatitis (11.4%), IgE-bound wheezing/asthma (10.8%) and food allergies (7.4%), and to much lesser extent those of allergic rhinitis (3.4%) and urticaria (1.7%). The significantly higher total IgE antibodies concentrations were found in children with allergy-like symptoms (p < 0.0005) (cut-off 15.15 kU/L, sensitivity 76.5% specificity 71.6%). Conclusion. Almost 20% of two-year-old children have any of clinically manifested allergic diseases, with atopic dermatitis and IgE wheeze/asthma being predominant. The higher total IgE antibodies concentration is a good marker for sensitization in children with allergy-like symptoms.


2011 ◽  
Vol 8 (4) ◽  
pp. 55-61
Author(s):  
N G Konyukova ◽  
A N Pampura ◽  
E S Fedenko ◽  
A I Khavkin ◽  
T S Okuneva ◽  
...  

Background. To establish the clinical and immunological features of the manifestations of allergic diseases in children with IgE-mediated sensitization to potato. Methods. allergy tests (skin prick tests and / or the determination of specific IgE in serum by ImmunoCap, Phadia was performed in 171 children with allergic diseases, who had sensitization to food plant proteins. Results. sensitization to the potato found in 134 children. significant discrepancies (36%) in the results of in vitro and in vivo tests to the potatoes were shown. sensitization to the potatoes is more common in patients with atopic dermatitis (ad), especially in severe disease. among children with the level of specific IgE antibodies to potato ≥2 kUa / l there were more common patients with severe ad. the correlation between the level of specific IgE antibodies to the potatoes and some of food plant proteins was found. the relationship between the concentration of specific IgE to the potatoes and Bet v 2 was not detected. Conclusion. the presence and concentration of specific IgE to the potatoes to a certain extent associated with clinical manifestations of ad. the data obtained substantiate the determination of specific IgE antibodies to potato in children with ad, especially in severe cases.


Author(s):  
Eisaku Iwasaki ◽  
Minoru Baba ◽  
Yoshinori Wagatsuma ◽  
Toshiko Yamaguchi ◽  
Norio Nemoto ◽  
...  

2014 ◽  
Vol 11 (1) ◽  
pp. 59-63
Author(s):  
V A Revyakina ◽  
T I Garaschenko ◽  
A M Samohvat

Background. Children with frequent acute respiratory viral infections and clinical symptoms of the upper respiratory tract are often prescribed unwarranted surgical treatment. The aim of this study was to assess the allergic reactivity in children with frequent acute respiratory viral infections and obstructed nasal breathing. Methods. The study included 48 children aged from 2 to 7 years old, 29 boys and 19 girls. Clinical examination including anamnesis morby and family anamnesis of allergy, endoscopic examination of the nose and nasopharynx, total and allergen-specific IgE determination were performed. Results. In 87,5% of children with frequent acute respiratory viral infections and previously diagnosed adenoid hypertrophy degree II-III with a block of auditory tube pharyngeal mouths or hypertrophy of adenoid hypertrophy with II degree pipe rollers, pipe tonsils, allergic rhinitis (?) hypersensitivity to house dust mites and in 54,1% to pollen was detected. In 25,0% of children allergen-specific IgE antibodies to food allergens (cow’s milk, nuts, grains, pears) were identified. 33,3% of children had high levels of allergen-specific IgE antibodies to cats and dogs epidermidis. Conclusion. Children with frequent acute respiratory viral infections and nasal obstruction require allergist survey to develop treatment strategies.


1995 ◽  
Vol 95 (3) ◽  
pp. 668-671 ◽  
Author(s):  
Cristina Pascual ◽  
Jesus F. Crespo ◽  
Joaquin Quiralte ◽  
Concepcion Lopez ◽  
Gary Wheeler ◽  
...  

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