scholarly journals Allergic rhinitis or adenoid vegetations/adenoids. Where is the truth?

2014 ◽  
Vol 11 (1) ◽  
pp. 59-63
Author(s):  
V A Revyakina ◽  
T I Garaschenko ◽  
A M Samohvat

Background. Children with frequent acute respiratory viral infections and clinical symptoms of the upper respiratory tract are often prescribed unwarranted surgical treatment. The aim of this study was to assess the allergic reactivity in children with frequent acute respiratory viral infections and obstructed nasal breathing. Methods. The study included 48 children aged from 2 to 7 years old, 29 boys and 19 girls. Clinical examination including anamnesis morby and family anamnesis of allergy, endoscopic examination of the nose and nasopharynx, total and allergen-specific IgE determination were performed. Results. In 87,5% of children with frequent acute respiratory viral infections and previously diagnosed adenoid hypertrophy degree II-III with a block of auditory tube pharyngeal mouths or hypertrophy of adenoid hypertrophy with II degree pipe rollers, pipe tonsils, allergic rhinitis (?) hypersensitivity to house dust mites and in 54,1% to pollen was detected. In 25,0% of children allergen-specific IgE antibodies to food allergens (cow’s milk, nuts, grains, pears) were identified. 33,3% of children had high levels of allergen-specific IgE antibodies to cats and dogs epidermidis. Conclusion. Children with frequent acute respiratory viral infections and nasal obstruction require allergist survey to develop treatment strategies.

2021 ◽  
Vol 20 (6) ◽  
pp. 125-135
Author(s):  
A. Yu. Ovchinnikov ◽  
◽  
N. A. Miroshnichenko ◽  
Yu. O. Nikolaeva ◽  
◽  
...  

Allergic rhinitis is characterized by a significant prevalence among the adult population. Patients with allergic diseases have a higher sensitivity to pathogens of acute respiratory infection of the upper respiratory tract (ARVI). Inflammation of the mucous membrane of the nasal cavity and paranasal sinuses in such patients is characterized by more pronounced symptoms and greater resistance to therapy. An observational study was conducted at the Department of Otorhinolaryngology of the Moscow State Medical University named after A. I. Evdokimov, during which the effect of modern antihistamines on the severity of nasal and non-nasal symptoms of inflammation was evaluated in patients who were diagnosed with the development of acute respiratory viral infections against the background of seasonal exacerbation of allergic rhinitis. The data of 50 patients divided into two groups were analyzed. In the first group (n = 25), benzhydrylpiperazinylbutylmethylxanthine succinate (Theoritin) was included in the therapy regimen, in the second – cetirizine preparations (n = 5). During the follow-up, each patient underwent a clinical assessment of the severity of nasal and non-nasal symptoms three times (1st, 7th and 14th days of follow-up), and the severity of nasal obstruction was assessed using anterior active rhinomanometry. According to the data obtained, there was a pronounced positive dynamics in both groups, while the clinical efficacy was confirmed by instrumental evaluation data. However, by the 7th day of treatment, the positive dynamics was more pronounced in the group of patients receiving theoritin as part of therapy. The use of modern antihistamines in patients comorbid for allergic rhinitis and acute respiratory diseases has a significant therapeutic effect. Theoritin provides more pronounced therapeutic effects in the early stages, which makes its further study and use of the drug for the treatment of acute respiratory viral infections against the background of allergic rhinitis promising.


2021 ◽  
pp. 212-219
Author(s):  
I. V. Koltuntceva ◽  
I. M. Gaiduk ◽  
L. V. Sakhno ◽  
S. V. Bairova

Due to the increase in the weight of allergic diseases in the general pathology of childhood, the diagnosis and treatment of allergic rhinitis in children and the management of these patients at the outpatient stage have not lost their relevance. The period of preschool and school age is characterized by a high frequency of acute respiratory diseases of the upper respiratory tract, especially acute rhinitis, rhinopharyngitis, rhinosinusitis. This daily poses to the district pediatrician the tasks of differential diagnosis of allergic rhinitis and acute rhinitis with a prolonged course. Allergic rhinitis most often does not require hospitalization and, with timely diagnosis, does not lead to serious consequences. It is known that children who are prone to allergies suffer from acute respiratory viral infections more often and more severely than their peers. An integrated approach to the diagnosis and treatment of such children with the participation of an allergist, an otorhinolaryngologist, under the constant supervision of a district pediatrician, the rational use of drug therapy can reduce the duration of the disease, improve the quality of life of the patient.The article presents generalized principles of management of patients with allergic rhinitis from the point of view of domestic and international recommendations, describes in detail the rules of life for children with allergic rhinitis, emphasizes the role of the district pediatrician in teaching parents to ensure a hypoallergenic environment of the child. The authors present a clinical example of the effective use of a combined decognensant and an antihistamine for the treatment of acute respiratory viral infections in a child with allergic rhinitis.


2015 ◽  
Vol 12 (2) ◽  
pp. 25-28
Author(s):  
M A Mokronosova ◽  
E A Bass ◽  
A M Bala ◽  
T M Zheltikova

Background. The purpose of this study was to identify IgE-antibodies to the major and minor allergenic components of pets in the blood serum of patients with bronchial asthma and/or allergic rhinitis (BA/AR). Methods. The study included 327 patients from Moscow and St. Petersburg. All of them were detected for specific IgE-antibodies (IgE-AB) to the animal allergens by ImmunoCAP® (ThermoFisherScientific, Sweden). 105 patients wanted to detect IgE-AB to the main animal allergens molecules ImmunoCAP ISAC® (ThermoFisherScientific, Sweden). Results. In the sera of 327 patients IgE-AB to cat’s (62%) allergen dominated. IgE-antibodies to dog’s, house dust mites (D.pteronyssinus, D. farinae), mold fungi, horses and rodents allergens were found in 2,6-31 times less. IgE-AB to uteroglobin (rFel d 1), major cat allergen, was detected in 80% of patients (84/105). The detection rate of IgE-AB to other cat allergens was 4,2-8 times lower (rFel d 2 - 10%, nFel d 4 - 19%). IgE-AB to major dog allergen rCan f 1 was detected in 39% of patients (41/105). Positive level of IgE-AB to other dog allergens was detected in 2,2-4,9 times lower (rCan f 2 - 8%, nCan f 3 - 9%, rCan f 5 - 18%). Positive level of IgE-AB to lipocalin was assayed in 6% of patients, to serum albumin - in 7%. Conclusion. Prevalence of IgE-AB to cat and dog allergens was almost 3 times higher than the frequency of detection of IgE-AB to house dust mite allergens in citizens of Moscow and S. Petersburg. The frequency of IgE-AB to rFel d 1 was dominated and detected 2 and 4-11 times often than to rCan f 1 and other animal allergens consequently.


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