scholarly journals The prevalence of DNA microsatellite instability in anaplastic thyroid carcinoma – systematic review and discussion of current therapeutic options

2021 ◽  
Vol 25 (3) ◽  
pp. 213-223
Author(s):  
Maria Linda Rocha ◽  
Kurt Werner Schmid ◽  
Piotr Czapiewski
Cancers ◽  
2020 ◽  
Vol 12 (9) ◽  
pp. 2585
Author(s):  
Aurora Mirabile ◽  
Matteo Biafora ◽  
Leone Giordano ◽  
Gianluigi Arrigoni ◽  
Maria Giulia Cangi ◽  
...  

Anaplastic thyroid carcinoma (ATC) is a very rare, highly aggressive malignant thyroid tumor with an overall survival from 3 to 5 months in most of the cases. Even the modern and intensive treatments seem not to be enough to provide a cure, also for the resectable ones, and the role of chemotherapy is still unclear but does not seem to prolong survival. Nevertheless, some patients survive longer and have a better outcome, even in the presence of metastasis, than what the literature reports. We present the case of a 64-year-old female affected by ATC, treated on February 2018 with surgery followed by chemoradiation. One year after surgery, the patient developed a subcutaneous recurrence that was radically resected and is still alive 29 months after the diagnosis. We propose a systematic review of the literature to deepen the knowledge of the prognostic factors of ATC with the aim to recognize and select the patients with a better outcome, even if metastatic, and to describe a very uncommon site of metastatization.


2015 ◽  
Vol 122 (03) ◽  
Author(s):  
V Tiedje ◽  
M Kroiß ◽  
K Lorenz ◽  
S Ting ◽  
M Stuschke ◽  
...  

2015 ◽  
Author(s):  
Paul Lennon ◽  
Sandra Deady ◽  
Marie-Louise Healy ◽  
John Kinsella ◽  
Conrad Timon ◽  
...  

2014 ◽  
Author(s):  
Husniye Baser ◽  
Mina Gulfem Kaya ◽  
Sefika Burcak Polat ◽  
Ersin Gurkan Dumlu ◽  
Canan Altunkaya ◽  
...  

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