scholarly journals Not Otherwise Specified-Type Sarcoma of Breast with CD10 Expression: Case Report

2019 ◽  
Vol 15 (4) ◽  
pp. 268-271
Author(s):  
Bermal Hasbay ◽  
◽  
Filiz Aka Bolat ◽  
Hulya Aslan ◽  
Huseyin Ozgur Aytac ◽  
...  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Sawsan Ismail ◽  
Munawar Hraib ◽  
Rana Issa ◽  
Thanaa Alassi ◽  
Zuheir Alshehabi

Abstract Background Ovarian steroid cell tumors represent a rare category of sex cord-stromal tumors that constitute less than 0.1% of all ovarian tumors. These neoplasms are classified into three main subtypes according to the cell of origin: Leidyg cell tumors, stromal luteomas, and steroid cell tumors not otherwise specified (SCTs-NOS). The latter subtype is defined as a neoplasm of an uncertain lineage that mostly affects middle-aged women, whereas it’s rare in younger ages. Case presentation We report a case of a 21-year-old virgin female who presented to our hospital with complaints of mild abdominal pain, hirsutism, and oligomenorrhea for more than a year. Before her current admission, the patient had attended an external gynecologic clinic where she had been prescribed oral contraceptives to regulate her periods. Nevertheless, on presentation to our institution, physical examination revealed abdominal tenderness with a palpable pelvic mass and mild hirsutism in the thigh. Ultrasonography demonstrated a large left ovarian mass measuring 154 × 104 mm, and compressing the uterus. Therefore, a unilateral salpingo-oophorectomy was performed, and interestingly, pathologic examination of the large aforementioned mass alongside with immunohistochemical correlation revealed the diagnosis of a large ovarian steroid cell tumor-not otherwise specified with a unique combination of benign and malignant features. Conclusions Although ovarian steroid cell tumors represent a rare category, they must be considered in the differential diagnosis for mild virilization symptoms in young females due to the importance of early diagnosis and management. In this manuscript, we aimed to present the first case report from Syria that highlights the crucial role of detailed morphological examination for challenging cases despite the difficulties in differential diagnosis, and the absence of ancillary techniques. Furthermore, we managed to discuss a brief review of diagnostic methods, histological characteristics, and treatment recommendations.


2017 ◽  
Vol 41 (S1) ◽  
pp. s856-s856
Author(s):  
S. Sanz Llorente ◽  
Z. González Vega ◽  
P. Bernal Romaguera ◽  
A.I. Ojeda Martinez ◽  
T. Ventura Faci ◽  
...  

IntroductionNowadays, 30% of the Spanish population suffers from some form of sleep disorder, occupying much of the visits to a psychiatrist. Sleep disorders are not a serious condition by itself, but have serious implications in daily life: physical exhaustion, poor performance, daytime sleepiness. Insomnia is a most common sleep disorder, however, hypersomnia must also be considered due to the limitations that it causes.ObjectiveBy the description of case report, we will carry out a review of the syndrome Kleine Levine.MethodsCase report.ResultsA case of Kleine–Levin syndrome in a 23-year-old male is described. The episodic disorder was characterized by excessive sleep, voracious appetite, hyper-sexuality, irritability and memory loss. Among its history, he included a psychotic episode in childhood and an episode of behavioral disorder caused by a stressful situation. His partner refers a similar episode of hypersomnia last year that was self-limiting in 15 days and he did not go to the doctor. Patients often act normal between episodes. Remission was spontaneous. Prospects, for organic aetiology, differential diagnosis. However, arises additional tests (analytical, brain CT, EEG…) resulted no pathological. Patient fulfilled the criteria for KLS, but due to the rarity of the disorder he was previously diagnosed as psychosis not otherwise specified.ConclusionsThis case report aim to highlight that KLS though considered a rare disorder but not uncommon and lack of enough available research data is likely to be responsible for missed or erroneous diagnosis; thus we require more systematic studies regarding etiologies and treatment.Disclosure of interestThe authors have not supplied their declaration of competing interest.


2005 ◽  
Vol 97 (1) ◽  
pp. 260-262 ◽  
Author(s):  
Ai-xia Liu ◽  
Jin Sun ◽  
Wen-qun Shao ◽  
Hang-mei Jin ◽  
Wei-qing Song

2019 ◽  
Vol 2 (1) ◽  
pp. 91-94
Author(s):  
S R Ohayi

Steroid cell tumour of the ovary is an extremely rare tumour. They are classified into three types with the commonest, the steroid cell tumour not otherwise specified (NOS) consisting approximately 60% of them. They occur mostly in middle age, are mostly benign and mostly cause virilising symptoms though a small proportion can present with oestrogenic effects. Diagnosis is based on presence of symptoms, presence of specific histopathological features with absence of certain histopathological features and positive specific immunostaining results. Here the author reports a case of a 42-year old woman with abdominal mass but without virilising symptoms but on whom a diagnosis of ovarian steroid cell tumour was reached by histopathological analysis which revealed presence of specific histopathological features with absence of certain histopathological features.


Author(s):  
Fathima Seles M. ◽  
M. Revathy ◽  
Madurai Padmanabhan Kanchana

Virilising ovarian tumours account for less than 5% of all ovarian tumours. A steroid cell tumour (SCTs) of the ovary comes under the sex cord stromal tumours and accounts for only 0.1% of all ovarian tumours. Almost 75% are functioning tumors with production of androgenic hormones causing virilisation and cushingoid features. They are usually unilateral, benign with only 25-45% malignant cases. Here authors report the incidence of steroid cell tumour in our institution and discuss about a 37-year-old woman with steroid cell tumour, not otherwise specified who presented with oligomenorrhea followed by amenorrhea, secondary infertility and signs of virilisation.


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