scholarly journals Adult type granulosa cell tumor of the testis: Radiological evaluation and review of the literature

2014 ◽  
Vol 40 (2) ◽  
pp. 115-119 ◽  
Author(s):  
Ioannis Tsitouridis ◽  
Charalampos Maskalidis ◽  
Aikaterini Sdrolia ◽  
Stavroula Pervana ◽  
Elissavet Pazarli ◽  
...  
Rare Tumors ◽  
2011 ◽  
Vol 3 (4) ◽  
pp. 117-119 ◽  
Author(s):  
Zhao Song ◽  
David J. Vaughn ◽  
Zhanyong Bing

Granulosa cell tumors can be classified into juvenile and adult types and more commonly occur in ovaries. Adult testicular granulosa cell tumors are extremely rare and only 29 cases of adult type have previously been reported. We report here a 28-year old Caucasian man with a left testicular adult type granulosa cell tumor. The tumor measured 2.6×2.6×2.5 cm and was mitotically active (10/10 HPF). Immunohistochemical stains showed the tumor diffusely positive for inhibin and vimentin, and negative for epithelial membrane antigen, cytokeratins, synaptophysin, HMB-45, OCT-4, placental-like alkaline phosphatase and lymphoid markers. The reported granulosa cell tumors in adult testis were briefly reviewed.


2006 ◽  
Vol 73 (3) ◽  
pp. 297-301
Author(s):  
G. Lucarelli ◽  
V. Mancini ◽  
G. Annunziata ◽  
S. Trabucco ◽  
S. Palazzo ◽  
...  

2014 ◽  
Vol 9 (1) ◽  
pp. 107 ◽  
Author(s):  
Thomas EO Schubert ◽  
Robert Stoehr ◽  
Arndt Hartmann ◽  
Sabrina Schöne ◽  
Mathias Löbelenz ◽  
...  

2017 ◽  
Vol 26 (4) ◽  
pp. 382-387
Author(s):  
Judit Tamás ◽  
Ildikó Vereczkey ◽  
Erika Tóth ◽  
Erzsébet Csernák ◽  
Katalin Purcsi ◽  
...  

A combination of ovarian tumors with the same histogenetic origin but different histologic subtype is relatively common, whereas a co-occurrence of tumors with different histogenetic origin is rare. We report a case of mixed ovarian tumor composed of Brenner tumor and adult-type granulosa cell tumor, a combination that to the best of our knowledge has not been reported in the literature until now.


2007 ◽  
Vol 25 (4) ◽  
pp. 322-325 ◽  
Author(s):  
Pasquale Ditonno ◽  
Giuseppe Lucarelli ◽  
Michele Battaglia ◽  
Vito Mancini ◽  
Silvano Palazzo ◽  
...  

Urology ◽  
2006 ◽  
Vol 68 (5) ◽  
pp. 1121.e13-1121.e16 ◽  
Author(s):  
Jorge Arzola ◽  
Robert L. Hutton ◽  
Steven M. Baughman ◽  
Rafael V. Mora

Author(s):  
Jessica A Pilsworth ◽  
Dawn R Cochrane ◽  
Samantha J Neilson ◽  
Bahar H Moussavi ◽  
Daniel Lai ◽  
...  

2011 ◽  
Vol 135 (1) ◽  
pp. 143-146 ◽  
Author(s):  
Joshua Anspach Hanson ◽  
Abiy B. Ambaye

Abstract Adult testicular granulosa cell tumors are rare sex cord–stromal tumors of which only 28 have been previously reported. As compared with their ovarian counterparts, these tumors may follow a more aggressive course because the proportion of malignant cases is higher. To date, there are no clinical or pathologic features that definitively predict malignancy. We reviewed all prior case reports for features that may predict their malignant potential. Tumor size greater than 5.0 cm is the only feature statistically associated with malignancy. Mitotic count, tumor necrosis, patient age, and the presence of gynecomastia do not, at present, predict benign versus malignant behavior.


2017 ◽  
Vol 1 (1) ◽  
pp. 12-14 ◽  
Author(s):  
Wei-Chieh Chen ◽  
◽  
Yun-Ho Lin ◽  
Shauh-Der Yeh ◽  
Chien-Chih Wu ◽  
...  

2019 ◽  
Vol 2019 ◽  
pp. 1-10
Author(s):  
Klaus-Peter Dieckmann ◽  
Julia Bertolini ◽  
Christian Wülfing

Adult granulosa cell tumor (AGCT) of the testis represents a very rare testicular neoplasm that is poorly understood clinically. Here we report the case of a 22-year-old male who presented with unspecific scrotal symptoms. Scrotal sonography disclosed a 6 mm hypoechoic intratesticular lesion. Histological examination after orchiectomy revealed a homogeneous and well demarcated neoplasm with monomorphic cells with nuclear grooving and microfollicular formation of the so-called Call-Exner bodies. Immunohistology showed positive stainings of vimentin, calretinin, and inhibin with negative stainings of the typical germ cell tumor markers. Thus, the diagnosis of a benign AGCT was made. The patient is well one year after surgery. A total of 91 previous AGCT cases were identified in the literature. Median age of the cases reported to date is 44 years, median tumor size 3.2 cm. 54.3% of the AGCT cases were located on the left side. 12 cases (13.2%) were of malignant nature. Testis-sparing surgery would be the treatment of choice, but only two of all cases had received that procedure. The present report aims to increase the clinical knowledge of AGCT and specifically to increase the clinician’s vigilance with respect to testis-sparing surgery in probably benign testicular masses.


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