Treatment of Recurrent Respiratory Papillomatosis: Case Series and Review of Technique

Author(s):  
Christopher Manley ◽  
Christoph Hutchinson ◽  
Amit Mahajan ◽  
Omar Ibrahim ◽  
Erik Folch ◽  
...  

Adult Recurrent Respiratory Papillomatosis (RRP) is a rare disease caused by the human papilloma virus in which papilloma grows from the respiratory epithelium. Patients can suffer from significant respiratory distress secondary to tracheal or bronchial obstruction by papilloma and the mainstay of treatment is bronchoscopic debridement. There are a variety of techniques to resect the endoluminal tumor, including CO2 or YAG laser, argon plasma coagulation, microdebrider and cold forceps. There have been documented cases of healthcare workers contracting HPV after exposure to surgical smoke during ablation of papilloma and measures should be taken to avoid inhalation of the smoke plume. For proximal lesions that are accessible to a microdebrider, this appears to be a safe and effective technique that does not generate heat or surgical smoke.

Endoscopy ◽  
2020 ◽  
Vol 52 (09) ◽  
pp. 812-813 ◽  
Author(s):  
Arvind J. Trindade ◽  
Diana Wee ◽  
Praneet Wander ◽  
Molly Stewart ◽  
Calvin Lee ◽  
...  

1997 ◽  
Vol 111 (4) ◽  
pp. 381-384 ◽  
Author(s):  
W. Bergler ◽  
M. Hönig ◽  
K. Götte ◽  
G. Petroianu ◽  
K. Hörmann

AbstractExtension of recurrent respiratory papillomatosis (RRP) to the lower airway in children is life-threatening and an extremely difficult condition to treat. We present the case of a seven-year-old girl with progressive RRP since the age of two. Repeated CO2 laser treatment and interferon-alpha treatment could not prevent tracheotomy and spread to the trachea. We used argon plasma coagulation (APC) with flexible endoscopy for the first time for the treatment of RRP. APC gives a controlled limited penetration into the tissue and good control of bleeding. There is no carbonization or vaporization which makes it a suitable method for the treatment of lower airway RRP. After a few treatments with APC, we gained very good control of the disease with no side-effects or complications. The described application of APC seems to be a promising way to treat lower airway RRP.


Author(s):  
Cláudia Macedo ◽  
Nuno Almeida ◽  
Ana Rita Alves ◽  
Ana Margarida Ferreira ◽  
Pedro Figueiredo

<b><i>Introduction:</i></b> Percutaneous endoscopic gastrostomy is a safe and effective technique and its use is widely spread. Peristomal leakage may occur within the first few days after gastrostomy tube placement and also in the mature gastrostomy tract. The initial treatment involves conservative measures. If the leakage does not resolve, different endoscopic interventions could be necessary with consequent impairing of enteral nutrition and, in some cases, the need of creating a new gastro-cutaneous fistula. <b><i>Case Report:</i></b> We present 4 consecutive cases complicated with late peristomal leakage and medical treatment failure. These patients underwent upper digestive endoscopy, and circumferential fulguration of the mucosa surrounding the tube with pulsed argon plasma coagulation (APC) at 50 W and 1 L/min flow rate was performed. Additional long through-the-scope clips were applied in 2 cases, since the inner orifice remained enlarged, in order to obtain a better closure. Complete leakage and skin changes resolution occurred between 2 and 6 weeks after the procedure (mean 3.5 weeks). The overall mean follow-up was 19 months after the endoscopic procedure (maximum 30 months, minimum 10 months). There was no recurrence of leakage. <b><i>Conclusion:</i></b> The use of APC alone or combined with long through-the-scope clips in large internal stoma orifice resolved persistent leakage from percutaneous endoscopic gastrostomy in all 4 presented cases without complications. In our case series, this technique appeared to be an effective, safe, and relatively low-cost alternative to the treatment of persistent peristomal leakage of the mature gastrostomy tract.


2016 ◽  
Vol 83 (5) ◽  
pp. AB512
Author(s):  
Thiago F. Souza ◽  
Lucas M. Marques ◽  
Felipe P. Santos ◽  
Gabriel C. Nunes ◽  
Sergio Barrichello ◽  
...  

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