Treatment of recurrent respiratory papillomatosis with argon plasma coagulation

AbstractExtension of recurrent respiratory papillomatosis (RRP) to the lower airway in children is life-threatening and an extremely difficult condition to treat. We present the case of a seven-year-old girl with progressive RRP since the age of two. Repeated CO2 laser treatment and interferon-alpha treatment could not prevent tracheotomy and spread to the trachea. We used argon plasma coagulation (APC) with flexible endoscopy for the first time for the treatment of RRP. APC gives a controlled limited penetration into the tissue and good control of bleeding. There is no carbonization or vaporization which makes it a suitable method for the treatment of lower airway RRP. After a few treatments with APC, we gained very good control of the disease with no side-effects or complications. The described application of APC seems to be a promising way to treat lower airway RRP.

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Case of Life-Threatening Gas Embolism Associated With Argon Plasma Coagulation

CHEST Journal ◽

10.1378/chest.10825 ◽

2010 ◽

Vol 138 (4) ◽

pp. 116A

Author(s):

Samaan Rafeq ◽

Sugantha Sundar ◽

Armin Ernst ◽

Adnan Majid

Keyword(s):

Argon Plasma Coagulation ◽

Argon Plasma ◽

Gas Embolism ◽

Plasma Coagulation ◽

Life Threatening

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Treatment of Recurrent Respiratory Papillomatosis: Case Series and Review of Technique

Surgical Technology Online ◽

10.52198/21.sti.38.gs1408 ◽

2021 ◽

Author(s):

Christopher Manley ◽

Christoph Hutchinson ◽

Amit Mahajan ◽

Omar Ibrahim ◽

Erik Folch ◽

...

Keyword(s):

Healthcare Workers ◽

Argon Plasma Coagulation ◽

Case Series ◽

Argon Plasma ◽

Recurrent Respiratory Papillomatosis ◽

Bronchial Obstruction ◽

Effective Technique ◽

Surgical Smoke ◽

Papilloma Virus ◽

Plasma Coagulation

Adult Recurrent Respiratory Papillomatosis (RRP) is a rare disease caused by the human papilloma virus in which papilloma grows from the respiratory epithelium. Patients can suffer from significant respiratory distress secondary to tracheal or bronchial obstruction by papilloma and the mainstay of treatment is bronchoscopic debridement. There are a variety of techniques to resect the endoluminal tumor, including CO2 or YAG laser, argon plasma coagulation, microdebrider and cold forceps. There have been documented cases of healthcare workers contracting HPV after exposure to surgical smoke during ablation of papilloma and measures should be taken to avoid inhalation of the smoke plume. For proximal lesions that are accessible to a microdebrider, this appears to be a safe and effective technique that does not generate heat or surgical smoke.

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Argon plasma coagulation (APC) ? Clinical usefulness in flexible endoscopy

Gastrointestinal Endoscopy ◽

10.1016/s0016-5107(96)80065-4 ◽

1996 ◽

Vol 43 (4) ◽

pp. 306 ◽

Cited By ~ 5

Author(s):

J.D. Waye ◽

K.E. Grund ◽

G. Farin

Keyword(s):

Argon Plasma Coagulation ◽

Argon Plasma ◽

Flexible Endoscopy ◽

Clinical Usefulness ◽

Plasma Coagulation

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Secondary pulmonary malignancies requiring interventional bronchoscopic procedures

Turkish Journal of Thoracic and Cardiovascular Surgery ◽

10.5606/tgkdc.dergisi.2021.19927 ◽

2021 ◽

Vol 29 (3) ◽

pp. 360-369

Author(s):

Efsun Gonca Uğur Chousein ◽

Demet Turan ◽

Mehmet Akif Özgül ◽

Erdoğan Çetinkaya

Keyword(s):

Airway Obstruction ◽

Clinical Characteristics ◽

Argon Plasma Coagulation ◽

Survival Rates ◽

Argon Plasma ◽

Shortness Of Breath ◽

Airway Patency ◽

Plasma Coagulation ◽

Life Threatening ◽

The Mean

Background: In this study, we aimed to share our singlecenter experience and to investigate the effect of interventional bronchoscopic procedures on secondary pulmonary malignancies in terms of complications, success, and survival rates. Methods: A total of 83 patients (42 males, 41 females; mean age: 57.8±15.2 years; range, 18 to 94 years) with secondary pulmonary malignancies who underwent interventional bronchoscopic procedures between January 2009 and December 2019 were retrospectively reviewed. Data including demographic and clinical characteristics of the patients, complications, and success and survival rates were recorded. Results: The most common secondary pulmonary malignancies were kidney and thyroid tumors with the complaints of cough, shortness of breath, and hemoptysis. The mean duration before the diagnosis was 34.7±52.8 (range, 0.1 to 219.3) months, and the mean survival after the diagnosis were 10±13.1 (range, 0.2 to 44.4) months. A total of 92% of the patients had an airway obstruction of >50% and the interventional bronchoscopic procedures such as argon plasma coagulation, laser, cryo, and mechanical resection were successful in achieving airway patency. Laser application was found to significantly improve survival (p=0.015). Acute complication rate was 8.4% and mortality rate was 0%. Conclusion: In patients with tracheobronchial lesions due to secondary pulmonary malignancies, interventional bronchoscopic procedures, regardless of the stage of the disease, provide rapid palliation in life-threatening symptoms such as dyspnea and hemoptysis due to airway obstruction, prolonging patient"s survival and gain time for additional treatments to take effect for primary disease.

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Hemospray® during Emergency Endoscopy: Indonesia’s First Experience from 37 Patients

Case Reports in Gastroenterology ◽

10.1159/000505775 ◽

2020 ◽

Vol 14 (1) ◽

pp. 70-79

Author(s):

Muhammad Begawan Bestari ◽

Ignatius Ronaldi Joewono ◽

Dolvy Girawan ◽

Jefry Tahari Argatio ◽

Siti Aminah Abdurachman

Keyword(s):

Mortality Rate ◽

Gastrointestinal Bleeding ◽

Argon Plasma Coagulation ◽

Argon Plasma ◽

Primary Treatment ◽

Emergency Endoscopy ◽

Plasma Coagulation ◽

Life Threatening ◽

Cook Medical ◽

Hemostatic Powder

Gastrointestinal bleeding (GIB) is one of the main indications for performing endoscopy; this condition can be life threatening. In some cases, emergency endoscopy (EE) is necessary to identify the source and stop the bleeding. Recently, hemostatic powder was introduced, one of which was Hemospray® (Cook Medical, Winston-Salem, NC, USA), which showed promising results for rapid hemostasis in primary treatment and salvage when conventional methods fails. Samples were taken retrospectively for a duration of 3 years since Hemospray was first introduced in Indonesia, from January 2016 to January 2019. The total number of EEs that used Hemospray were 37 procedures for 37 patients; 21 (56.8%) were males and 16 (43.2%) were females, while the average age was 67.8 years. Hemospray was used for upper GIB in 30 cases (81.1%) and for lower GIB in 7 (18.9%). Hemospray was used as monotherapy for 24 patients (64.9%) and as secondary modality for 13 (35.1%). The primary treatment was argon plasma coagulation in 8 cases (21.6%), adrenaline in 4 (10.8%), and Histoacryl® in 1 (2.7%). The mortality rate was 37.8% (n = 14); most deaths occurred within 30 days after the EE was performed, and none of the deaths was related to endoscopy or GIB. Hemospray was able to achieve hemostasis in all cases. Furthermore, there was no event of rebleeding. When conventional modalities alone were inadequate, the combination with Hemospray appeared to be able to control the bleeding. One of the main advantages of Hemospray is the ease in reaching difficult areas, and it require less skill compared to conventional modalities.

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Argon plasma coagulation in therapeutic endoscopy

Gastrointestinal Nursing ◽

10.12968/gasn.2019.17.sup8.s15 ◽

2019 ◽

Vol 17 (Sup8) ◽

pp. S15-S21

Author(s):

Anuj Abraham

Keyword(s):

Argon Plasma Coagulation ◽

Argon Plasma ◽

Flexible Endoscopy ◽

Therapeutic Endoscopy ◽

Target Tissue ◽

Plasma Coagulation ◽

Patient Preparation ◽

Effective Use ◽

Reduced Time ◽

Insight Into

Argon plasma coagulation (APC) is used widely and effectively in therapeutic gastrointestinal endoscopy, mainly to achieve both haemostasis and tissue ablation. The main advantages of APC treatment are its ease of application, cost effectiveness, improved safety and reduced time for application. This review gives an insight into the safe and effective use of APC in the gastrointestinal tract with flexible endoscopy. It discusses the technical aspects of the APC generator, the different types of APC probes tailored to the indication and the target tissue. It also discusses patient preparation, including the optimal pre- and post-APC care instructions.

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