CLOUD-BASED IT MANAGEMENT IMPACTS - Qualitative Weaknesses and Strengths of Clouds

2011 ◽  
Keyword(s):  
It Management

Die Norm ISO 20000 für das IT-Management

2010 ◽  
Vol 39 (6) ◽  
pp. 302-306
Author(s):  
Georg Disterer
Keyword(s):  
It Management

Handbuch IT-Management

2020 ◽  
pp. I-XXVII
Author(s):  
Ernst Tiemeyer
Keyword(s):  
It Management

Problems IT Management in Universities

2017 ◽  
Author(s):  
Bojidar V. Bojinov
Keyword(s):  
It Management

IT management issues in the 1990s

1991 ◽  
Vol 2 (4) ◽  
pp. 149
Author(s):  
Simon Holloway
Keyword(s):  
It Management ◽  
Management Issues

scholarly journals Prolonged efficacy of pembrolizumab in a patient presenting a multi-treated metastatic hepatocholangiocarcinoma

2020 ◽  
Vol 13 ◽  
pp. 175628482093518 ◽  
Author(s):  
Angélique Saint ◽  
Maxime Benchetrit ◽  
Sébastien Novellas ◽  
Denis Ouzan ◽  
Alexander Tuan Falk ◽  
...  
Keyword(s):  
Therapeutic Strategy ◽  
Complete Response ◽  
It Management ◽  
Tumor Control ◽  
Line Treatment ◽  
Viral Hepatitis C ◽  
Programmed Cell Death 1 ◽  
First Time ◽  
Inhibitor Treatment ◽  
Over Time

Introduction: Hepatocholangiocarcinoma (HCC-ICC) is a rare tumor presenting the histologic characteristics of both hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC). As there is no consensus on it management, the therapeutic strategy rests on the specific treatments for HCC or ICC. Programmed cell death 1 (PD-1) inhibitors showed encouraging results in the second line treatment of HCC after sorafenib but it efficacy in HCC-ICC has never been reported. Methods and results: We present the case of a 72-year-old male patient treated for metastatic HCC-ICC due to a viral hepatitis C cirrhosis in progression after two lines of treatment. Tumor was characterized by a PDL-1 status of 85%. Patient received pembrolizumab at doses of 200 mg every 21 days by intravenous infusion. After one injection he was presented an immediate clinical benefit, a partial response was observed after two months of treatment and a complete response two months later. This response was maintained over time along with toxicity-free tumor control after 18 months treatment. Conclusion: To our knowledge, we reported for the first time the efficacy of a PD1 inhibitor treatment in a patient presenting metastatic HCC-ICC due to viral cirrhosis and overexpressing PDL-1 after failure of two lines of treatment.

IT management capability and its impact on the performance of a CIO

2011 ◽  
Vol 48 (4-5) ◽  
pp. 145-156 ◽  
Author(s):  
Yi-Cheng Chen ◽  
Jen-Her Wu
Keyword(s):  
It Management ◽  
Management Capability

The Effect of Information Technology Steering Committees on Perceived IT Management Sophistication in Hotels

2013 ◽  
Vol 14 (1) ◽  
pp. 1-22 ◽  
Author(s):  
Cihan Cobanoglu ◽  
Baker Ayoun ◽  
Daniel Connolly ◽  
Khaldoon Nusair
Keyword(s):  
Information Technology ◽  
It Management

Social audit and accountability in IT management

2003 ◽  
Vol 18 (3) ◽  
pp. 166-179 ◽  
Author(s):  
Branka Mraovic´
Keyword(s):  
It Management ◽  
Social Audit
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