2017 ◽  
Vol 2 (17) ◽  
pp. 63-72
Author(s):  
Suzanna Bright ◽  
Chisomo Selemani

Functional approaches to disability measurement in Zambia reveals an overall disability prevalence rate of 13.4%, 4% of whom are recorded as having “speech impairment” (Zambia Federation of the Disabled [ZAFOD], 2006). Further, multidimensional poverty assessments indicate that 48.6% of Zambia's approximately 16 million citizens are impoverished. Currently, there are three internationally qualified speech-language pathologists (SLPs) providing services within Zambia's capital city, Lusaka. Given these statistics, it follows that a significant number of Zambian's, experiencing communication disability, are unable to access specialist assessment and support. Over the past decade, Zambia has seen two very different approaches to address this service gap—firstly, a larger scale top-down approach through the implementation of a formal master's degree program and more recently a smaller scale, bottom-up approach, building the capacity of existing professionals working in the field of communication disability. This article provides an overview of both programs and the context, unique to Zambia, in which they have developed. Authors describe the implementation challenges encountered and program successes leading to a discussion of the weakness and merits to both programs, in an attempt to draw lessons from which future efforts to support communication disability and SLP service development in Majority World contexts may benefit.


2003 ◽  
Vol 14 (6) ◽  
pp. 515-528 ◽  
Author(s):  
Chor Min Tan ◽  
Mark A. Beach ◽  
Andrew Nix

2019 ◽  
Author(s):  
Mahendra Awale ◽  
Finton Sirockin ◽  
Nikolaus Stiefl ◽  
Jean-Louis Reymond

<div>The generated database GDB17 enumerates 166.4 billion possible molecules up to 17 atoms of C, N, O, S and halogens following simple chemical stability and synthetic feasibility rules, however medicinal chemistry criteria are not taken into account. Here we applied rules inspired by medicinal chemistry to exclude problematic functional groups and complex molecules from GDB17, and sampled the resulting subset evenly across molecular size, stereochemistry and polarity to form GDBMedChem as a compact collection of 10 million small molecules.</div><div><br></div><div>This collection has reduced complexity and better synthetic accessibility than the entire GDB17 but retains higher sp 3 - carbon fraction and natural product likeness scores compared to known drugs. GDBMedChem molecules are more diverse and very different from known molecules in terms of substructures and represent an unprecedented source of diversity for drug design. GDBMedChem is available for 3D-visualization, similarity searching and for download at http://gdb.unibe.ch.</div>


Author(s):  
E. E. Maslak ◽  
I. V. Fomenko

Relevance. The role of pediatric dentistry in younger generation health improvement is undeniable; therefore, developing pediatric dental service is an important health care issue.Purpose. To present the contribution of Lubov Sergeevna Litovkina to paediatric dental service development in connection with her death on December, 23, 2019.Materials and methods. Based on the analysis of professional activity and scientific works of L.S. Litovkina the achievements that have contributed to the development of pediatric dentistry service in Volgograd Region were identified.Results. Public, clinical and scientific activities of L.S. Litovkina were highlighted. Special attention was paid to such areas of her work as the organization of epidemiological dental examinations of children’s population, the implementation of milk fluoridation program for prevention of dental caries in preschool children, school dentistry improvement and applying the dental educational program for the elementary schoolchildren.Conclusions. The organizational and scientific activities of L.S. Litovkina contributed to the development of the paediatric dental service and oral health improvement of children’s population.


Sign in / Sign up

Export Citation Format

Share Document