scholarly journals Strategi Usaha Restoran di Kawasan Pariwisata Lebih, Kabupaten Gianyar pada Era Adaptasi Kebiasaan Baru (Studi Kasus di Restoran Genius Café Vision dan Restoran Andrawina)

2021 ◽  
Vol 9 (2) ◽  
pp. 68-78
Author(s):  
I Nyoman Arcana Arcana ◽  
I Nyoman Wiratnaya

  Semenjak WHO (World Healthy Organization) mengumumkan bahwa COVID-19 merupakan pandemi, perilaku konsumen di berbagai sektor bisnis berubah, termasuk pada industri restoran dan rumah makan. Tujuan dari penelitian ini adalah untuk mengetahui dampak wabah Pandemi Covid-19 bagi usaha restoran di Kawasan Pariwisata Lebih, Kabupaten Gianyar dan untuk merumuskan strategi bertahan bagi pengelola restoran di kawasan tersebut pada era kebiasaan normal baru. Sampel penelitian ini adalah pengelola Genius Cafe Vision Gianyar dan pengelola restoran Andrawina (Rumah Luwih) Gianyar. Restoran Andrawina dan Genius Café Vision telah merancang strategi yang jelas untuk bisa meraih kepercayaan konsumen,namun di masa Pandemi Covid-19 ini terlihat jelas bahwa perbedaan segmen pasar sangat berpengaruh terhadap pendapatan restoran. Penelitian ini menyimpulkan bahwa Pandemi Covid-19 secara umum telah menyebabkan industri restoran di Kawasan Pariwisata Lebih, Kabupaten Gianyar mengalami penurunan pendapatan secara signifikan. Restoran yang masih beroperasi secara terbatas terus melakukan adaptasi operasional di masa Pandemi Covid-19 dengan cara mengurangi jenis dan variasi menu yang dijual, penerapan metode pelayanan antar jemput, pengurangan jam operasional restoran, pengurangan jumlah kapasitas maksimum pengunjung, pengurangan jumlah staf, penuruan harga jual menu, pengurangan ukuran porsi makanan, perubahan strategi pemasaran dan penerapan protokol kesehatan di restoran. Penelitian ini menemukan bahwa strategi pengelola restoran di Kawasan Pariwisata Lebih pada Era Adaptasi Kebiasaan Baru adalah “Strategi Bertahan” atau “Survival Strategy” dan “Strategi Tutup” atau “Closed and Decline Strategy”.  

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Yifat Ofir-Birin ◽  
Hila Ben Ami Pilo ◽  
Abel Cruz Camacho ◽  
Ariel Rudik ◽  
Anna Rivkin ◽  
...  

AbstractPathogens are thought to use host molecular cues to control when to initiate life-cycle transitions, but these signals are mostly unknown, particularly for the parasitic disease malaria caused by Plasmodium falciparum. The chemokine CXCL10 is present at high levels in fatal cases of cerebral malaria patients, but is reduced in patients who survive and do not have complications. Here we show a Pf ‘decision-sensing-system’ controlled by CXCL10 concentration. High CXCL10 expression prompts P. falciparum to initiate a survival strategy via growth acceleration. Remarkably, P. falciparum inhibits CXCL10 synthesis in monocytes by disrupting the association of host ribosomes with CXCL10 transcripts. The underlying inhibition cascade involves RNA cargo delivery into monocytes that triggers RIG-I, which leads to HUR1 binding to an AU-rich domain of the CXCL10 3’UTR. These data indicate that when the parasite can no longer keep CXCL10 at low levels, it can exploit the chemokine as a cue to shift tactics and escape.


2020 ◽  
Author(s):  
Pradip Kumar Tarafdar ◽  
Avijit Sardar ◽  
Aritraa Lahiri ◽  
Mithila Kamble ◽  
Amirul I. Mallick

The Lancet ◽  
2005 ◽  
Vol 365 (9461) ◽  
pp. 754 ◽  
Author(s):  
Jean HD Fasel ◽  
Philippe Morel ◽  
Philippe Gailloud
Keyword(s):  

1999 ◽  
Vol 9 (5) ◽  
pp. 602-619 ◽  
Author(s):  
Monica Hardesty ◽  
Timothy Black

2006 ◽  
Vol 72 (5) ◽  
pp. 3482-3488 ◽  
Author(s):  
M�nica Ordax ◽  
Ester Marco-Noales ◽  
Mar�a M. L�pez ◽  
Elena G. Biosca

ABSTRACT Copper compounds, widely used to control plant-pathogenic bacteria, have traditionally been employed against fire blight, caused by Erwinia amylovora. However, recent studies have shown that some phytopathogenic bacteria enter into the viable-but-nonculturable (VBNC) state in the presence of copper. To determine whether copper kills E. amylovora or induces the VBNC state, a mineral medium without copper or supplemented with 0.005, 0.01, or 0.05 mM Cu2+ was inoculated with 107 CFU/ml of this bacterium and monitored over 9 months. Total and viable cell counts were determined by epifluorescence microscopy using the LIVE/DEAD kit and by flow cytometry with 5-cyano-2,3-ditolyl tetrazolium chloride and SYTO 13. Culturable cells were counted on King's B nonselective solid medium. Changes in the bacterial morphology in the presence of copper were observed by scanning electron microscopy. E. amylovora entered into the VBNC state at all three copper concentrations assayed, much faster when the copper concentration increased. The addition of different agents which complex copper allowed the resuscitation (restoration of culturability) of copper-induced VBNC cells. Finally, copper-induced VBNC cells were virulent only for the first 5 days, while resuscitated cells always regained their pathogenicity on immature fruits over 9 months. These results have shown, for the first time, the induction of the VBNC state in E. amylovora as a survival strategy against copper.


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