scholarly journals Synthesis and biological evaluation of indeno[1, 2-b]indole derivatives as dual topoisomerase I & II inhibitors: novel multidrug resistant reversal anticancer agents

2019 ◽  
Vol 28 (11) ◽  
pp. 786-801
Keyword(s):  
Anticancer Agents ◽  
Topoisomerase I ◽  
Multidrug Resistant ◽  
Biological Evaluation ◽  
Indole Derivatives ◽  
Synthesis And Biological Evaluation

scholarly journals Synthesis and biological evaluation of 1-(2-(adamantane-1-yl)-1H-indol-5-yl)-3-substituted urea/thiourea derivatives as anticancer agents

RSC Advances ◽  
2017 ◽  
Vol 7 (81) ◽  
pp. 51640-51651 ◽  
Author(s):  
Hongyu Hu ◽  
Chunrong Lin ◽  
Mingtao Ao ◽  
Yufen Ji ◽  
Bowen Tang ◽  
...  
Keyword(s):  
Anticancer Agents ◽  
Biological Evaluation ◽  
Dependent Manner ◽  
Indole Derivatives ◽  
Thiourea Derivatives ◽  
H460 Cells ◽  
Dose Dependent ◽  
Synthesis And Biological Evaluation ◽  
Substituted Urea

A series of novel 2,5-disubstituted indole derivatives were synthesized. Compounds 7n, 7s, and 7w induced Nur77-expression in a time- and dose- dependent manner in H460 cells. Furthermore, Nur77 served as a critical mediator for the anticancer action of 7s.

Synthesis and Biological Evaluation of 1,5-Naphthyridines as Topoisomerase I Inhibitors. A New Family of Antiproliferative Agents

2015 ◽  
Vol 14 (23) ◽  
pp. 2722-2728 ◽  
Author(s):  
Concepcion Alonso ◽  
Maria Fuertes ◽  
Maria Gonzalez ◽  
Alicia Rodriguez-Gascon ◽  
Gloria Rubiales ◽  
...  
Keyword(s):  
Topoisomerase I ◽  
Biological Evaluation ◽  
Antiproliferative Agents ◽  
Topoisomerase I Inhibitors ◽  
New Family ◽  
Synthesis And Biological Evaluation

Synthesis and Biological Evaluation of 1,3,4-Thiadiazole Linked Phthalimide Derivatives as Anticancer Agents

2017 ◽  
Vol 14 (10) ◽  
Author(s):  
Zahra Rezaei ◽  
Setareh Moghimi ◽  
Rezvan Javaheri ◽  
Mehdi Asadi ◽  
Mohammad Mahdavi ◽  
...  
Keyword(s):  
Anticancer Agents ◽  
Biological Evaluation ◽  
Synthesis And Biological Evaluation

Synthesis and biological evaluation of N-glucosyl indole derivatives as sodium-dependent glucose co-transporter 2 inhibitors

2019 ◽  
Vol 83 ◽  
pp. 520-525 ◽  
Author(s):  
Kuang-Feng Chu ◽  
Jen-Shin Song ◽  
Chiung-Tong Chen ◽  
Teng-Kuang Yeh ◽  
Tsung-Chih Hsieh ◽  
...  
Keyword(s):  
Biological Evaluation ◽  
Indole Derivatives ◽  
Sodium Dependent ◽  
Synthesis And Biological Evaluation
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