scholarly journals Absence of influence of the Korean MELD score-based liver allocation system on pretransplant MELD score in patients undergoing living donor liver transplantation

2021 ◽  
Vol 1 (1) ◽  
pp. 10-17
Author(s):  
Sang Hoon Kim ◽  
Shin Hwang ◽  
Chul-Soo Ahn ◽  
Deok-Bog Moon ◽  
Tae-Yong Ha ◽  
...  
ISRN Surgery ◽  
2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Klaus Steinbrück ◽  
Marcelo Enne ◽  
Reinaldo Fernandes ◽  
Jose M. Martinho ◽  
Lúcio F. Pacheco-Moreira

Caroli's disease (CD) is a rare autosomal recessive disorder characterized by intrahepatic cystic dilatation of the bile ducts. Patients with bilobar or progressive disease may require orthotopic liver transplantation (OLT). In the MELD era, living donor liver transplantation (LDLT) raised as the ultimate treatment option for these patients, once their MELD score is usually low. Herein, we describe 2 cases of patients (a 2-year-old girl and a 19-year-old teenager) that successfully underwent LDLT as a treatment for diffuse CD. The good postoperative courses of the two cases indicate that LDLT is a feasible option in the treatment of this disorder, even in complicated or early age patients.


2018 ◽  
Vol 28 (3) ◽  
pp. 213-219
Author(s):  
Amr Badawy ◽  
Toshimi Kaido ◽  
Yuhei Hamaguchi ◽  
Takayuki Anazawa ◽  
Shintaro Yagi ◽  
...  

Background: To improve the outcome of living donor liver transplantation (LDLT), a scoring system that could predict accurately the patient and graft survival posttransplant is necessary. The aim of this study is to evaluate our previously proposed Muscle-model for end-stage liver disease (M-MELD) score and to compare it with the other available scores to find the best system that correlates with postoperative outcome after liver transplant. Methods: We retrospectively reviewed the data of 199 patients who underwent LDLT from January 2010 to July 2016 and calculated the preoperative MELD, MELD Na, the product of donor age and MELD (D-MELD), M-MELD, integrated MELD, and the balance of risk (BAR) score in all patients. The area under the receiver operating characteristics curves (AUCs) of each score was computed and compared at 3-, 6-months, and 1-year after LDLT. Results: The M-MELD, D-MELD, and integrated MELD had a good discriminative performance in predicting 3-month mortality after LDLT with AUCs > 0.7, while the M-MELD was the only score that showed a good discriminative performance in predicting 6-month and 1-year mortality after LDLT with AUCs > 0.7. Conclusion: Muscle-MELD score is a simple and useful predictor of patient survival after LDLT which showed a better predictive performance than other available scores.


2012 ◽  
Vol 49 (2) ◽  
pp. 157-161 ◽  
Author(s):  
Rogério Camargo Pinheiro Alves ◽  
Eduardo Antunes da Fonseca ◽  
Carla Adriana Loureiro de Mattos ◽  
Sofia Abdalla ◽  
José Eduardo Gonçalves ◽  
...  

CONTEXT: Living donor liver transplantation has become an alternative to reduce the lack of organ donation. OBJECTIVE: To identify factors predictive of early graft loss in the first 3 months after living donor liver transplantation. METHODS: Seventy-eight adults submitted to living donor liver transplantation were divided into group I with 62 (79.5%) patients with graft survival longer than 3 months, and group II with 16 (20.5%) patients who died and/or showed graft failure within 3 months after liver transplantation. The variables analyzed were gender, age, etiology of liver disease, Child-Pugh classification, model of end-stage liver disease (MELD score), pretransplantation serum sodium level, and graft weight-to-recipient body weight (GRBW) ratio. The GRBW ratio was categorized into < 0.8 and MELD score into >18. The chi-square test, Student t-test and uni- and multivariate analysis were used for the evaluation of risk factors for early graft loss. RESULTS: MELD score <18 (P<0.001) and serum sodium level > 135 mEq/L (P = 0.03) were higher in group II than in group I. In the multivariate analysis MELD scores > 18 (P<0.001) and GRBW ratios < 0.8 (P<0.04) were significant. CONCLUSIONS: MELD scores >18 and GRBW < 0.8 ratios are associated with higher probability of graft failure after living donor liver transplantation.


2016 ◽  
Vol 100 (11) ◽  
pp. 2416-2423 ◽  
Author(s):  
Yuhei Hamaguchi ◽  
Toshimi Kaido ◽  
Shinya Okumura ◽  
Atsushi Kobayashi ◽  
Hisaya Shirai ◽  
...  

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