scholarly journals A patient with pleuritic chest pain and abnormal blood clotting tests

2014 ◽  
Vol 13 (4) ◽  
pp. 174-177
Author(s):  
Anastasia Vamvakidou ◽  
◽  
Dimitris Konstantinou ◽  
Sohail Salam ◽  
Mohsen Mahmoud ◽  
...  
Keyword(s):  
Pulmonary Embolism ◽  
Chest Pain ◽  
Antiphospholipid Syndrome ◽  
Partial Thromboplastin Time ◽  
Blood Clotting ◽  
Activated Partial Thromboplastin Time ◽  
Pleuritic Chest Pain ◽  
Initial Management ◽  
Acute Setting

We present the case of a 58 year old man who developed pleuritic chest while an in-patient; investigations revealed pulmonary embolism, despite a significantly raised Activated Partial Thromboplastin Time (APTT), which was subsequently attributed to Antiphospholipid syndrome (APS). The diagnosis and initial management of APS in the acute setting is discussed.

scholarly journals Problem based review: Pleuritic Chest Pain

2012 ◽  
Vol 11 (3) ◽  
pp. 172-182
Author(s):  
Richard William Lee ◽  
◽  
Luke Eliot Hodgson ◽  
Mark Basil Jackson ◽  
Nick Adams ◽  
...  
Keyword(s):  
Pulmonary Embolism ◽  
Chest Pain ◽  
Pulmonary Embolus ◽  
Clinical Symptoms ◽  
Diagnostic Tools ◽  
Pleuritic Chest Pain ◽  
Common Causes ◽  
Wells Score ◽  
Current Guidelines ◽  
Symptoms And Signs

Pleuritic pain, a sharp discomfort near the chest wall exacerbated by inspiration is associated with a number of pathologies. Pulmonary embolus and infection are two common causes but diagnosis can often be challenging, both for experienced physicians and trainees. The underlying anatomy and pathophysiology of such pain and the most common aetiologies are presented. Clinical symptoms and signs that may arise alongside pleuritic pain are then discussed, followed by an introduction to the diagnostic tools such as the Wells’ score and current guidelines that can help to select the most appropriate investigation(s). Management of pulmonary embolism and other common causes of pleuritic pain are also discussed and highlighted by a clinical vignette.

Use of the Activated Partial Thromboplastin Time in the Control of Heparin Administration

1966 ◽  
Vol 12 (5) ◽  
pp. 263-268 ◽  
Author(s):  
Jane G Lenahan ◽  
Sheldon Frye ◽  
George E Phillips
Keyword(s):  
Therapeutic Range ◽  
Whole Blood ◽  
Partial Thromboplastin Time ◽  
Blood Clotting ◽  
Heparin Therapy ◽  
Activated Partial Thromboplastin Time ◽  
Clotting Time ◽  
Heparin Administration ◽  
Blood Clotting Time

Abstract The activated partial thromboplastin time (APTT) was compared to the whole blood clotting time (WBCT) as a control of heparin administration. The APTT was shown to be a sensitive system for the control of heparin therapy, with the added advantage that the blood can be drawn and taken to the laboratory for assay. The effective therapeutic range in man remains to be established.

Acute Pericardial Fat Necrosis

2010 ◽  
pp. 305-308
Author(s):  
Edward C. Rosenow
Keyword(s):  
Myocardial Infarction ◽  
Pulmonary Embolism ◽  
Differential Diagnosis ◽  
Chest Pain ◽  
Fat Necrosis ◽  
Pleuritic Chest Pain ◽  
Pericardial Fat

• Mostly left-sided • Affects females more than males • Acute severe pleuritic chest pain ∘ Differential diagnosis • Myocardial infarction • Pericarditis • Pulmonary embolism • Obesity may or may not be present • On CT, necrosis produces irregularity mimicking neoplasm but also fat density...

scholarly journals Pleuritic chest pain: infection, infarction or musculoskeletal?

2002 ◽  
Vol 1 (2) ◽  
pp. 64-66
Author(s):  
S Gill ◽  
◽  
A Pope ◽  
Keyword(s):  
Pulmonary Embolism ◽  
Chest Pain ◽  
Initial Presentation ◽  
Pulmonary Emboli ◽  
Pleuritic Chest Pain ◽  
X Ray ◽  
Blood Tests ◽  
Chest X Ray ◽  
Initial Blood ◽  
D Dimer

A 52 year old patient, originally thought to have musculoskeletal chest pain was found to have features consistent with infective pleurisy on initial blood tests and chest x-ray, with a negative d-dimer indicating a low likelihood of pulmonary embolism. Two weeks later he represented with continued symptoms and investigations revealed extensive pulmonary emboli, which were thought to have developed after his initial presentation.

Respiratory Dead Space Measurement in the Investigation of Pulmonary Embolism in Outpatients With Pleuritic Chest Pain

CHEST Journal ◽  
2005 ◽  
Vol 128 (4) ◽  
pp. 2195-2202 ◽  
Author(s):  
Kerstin Hogg ◽  
Deborah Dawson ◽  
Ted Tabor ◽  
Beverly Tabor ◽  
Kevin Mackway-Jones
Keyword(s):  
Pulmonary Embolism ◽  
Chest Pain ◽  
Dead Space ◽  
Pleuritic Chest Pain ◽  
Space Measurement ◽  
Respiratory Dead Space
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