scholarly journals Miller-Fisher syndrome after COVID-19 (Case report and literature review)

2021 ◽  
Author(s):  
Vinicius Aldo Cury ◽  
Bruna Pereira Correia ◽  
Leonardo Valente de Camargo ◽  
Juliana Passos ◽  
Gustavo Mafei Fores ◽  
...  
Keyword(s):  
Case Report ◽  
Neurological Complications ◽  
Tertiary Hospital ◽  
Symptomatic Improvement ◽  
Miller Fisher Syndrome ◽  
Level Of Evidence ◽  
Fisher Syndrome ◽  
Immune Mediated ◽  
Rare Case Report ◽  
Demyelinating Neuropathies

Background: Infection with SARS-CoV-2 can cause COVID-19, which mainly affects the respiratory system. However, neurological complications are frequent, including the group of acquired immune-mediated demyelinating neuropathies (NDAI), including Miller-Fisher syndrome (SMF), characterized by the triad of ophthalmoparesis, ataxia and areflexia. Infection with C. jejuni is the main precipitant of NDAI, but viruses are also related. Objectives: This report aims to describe a case of SMF with concomitant SARS-CoV-2 infection, seen at a tertiary hospital in Northern Paraná and to compare it with the literature. Design and setting: case report of a patient at the hospital neurology service of the Evangelical Hospital, Londrina, Paraná, Brazil. Methods: Report a case of SMF right after confirmation of COVID-19 seen at a tertiary hospital in Northern Paraná and compare it with the literature. Results: Male, 70 years old, white, evolved with progressive and symmetrical crural paraparesis 17 days after confirmation of COVID-19. Upon admission, he presented ataxia, paraesthesia, and crural myotactic areflexia with no signs of pyramidal release, and a score on the Medical Research Council (MRC) muscle strength scale of 58 points. Analysis of CSF with albumin-cytological dissociation. Treatment was performed with intravenous human immunoglobulin (IVIG) and discharged after six days of hospitalization with partial symptomatic improvement. We compared this case with those described in the published literature. Not found Brazilian case published to date. Conclusion: Rare case report of SMF by SARS-CoV-2. The relationship has consistency, temporality, biological plausibility, coherence and analogy compatible with the current literature. Studies with a higher level of evidence are needed to determine the strength of such an association.

Miller Fisher Syndrome with GBS Overlap- a Rare Case Report

2011 ◽  
Vol 3 (8) ◽  
pp. 568-569
Author(s):  
Dr Manas Ranjan Sahoo ◽  
◽  
Dr Manas Ranjan Rout
Keyword(s):  
Case Report ◽  
Rare Case ◽  
Miller Fisher Syndrome ◽  
Fisher Syndrome ◽  
Rare Case Report

scholarly journals Anti-Ganglioside Antibody Negative Miller Fisher Syndrome with Atypical Features: A Case Report

2021 ◽  
Vol 07 (02) ◽  
pp. 26-28
Author(s):  
Naresh Kumar ◽  
Keyword(s):  
Case Report ◽  
Miller Fisher Syndrome ◽  
Serological Marker ◽  
Fisher Syndrome ◽  
Immune Mediated ◽  
Negative Case ◽  
Diagnostic Clue ◽  
Clinical Triad ◽  
Classical Triad ◽  
Symptoms And Signs

Miller Fisher Syndrome (MFS), a variant of Guillain Barre Syndrome (GBS), is an immune-mediated neuropathy presenting with the classical clinical triad of ophthalmoplegia, ataxia, and areflexia. Although the clinical triad is the cardinal diagnostic clue, it can also present with a variety of other atypical neurological symptoms and signs beyond the classical triad. IgG anti-GQ1b antibodies are a powerful serological marker for the diagnosis of MFS, however, they can be absent in 10-15% cases of MFS. Here, we are describing a case of a 55-year old lady with an anti-ganglioside negative case of MFS with ptosis and bulbar palsy, who improved with IVIg.

scholarly journals Recurrent Miller Fisher syndrome: Case report

2021 ◽  
Author(s):  
A. Peral Quirós ◽  
F. Acebrón ◽  
M. del Carmen Blanco Valero ◽  
F. Labella Álvarez
Keyword(s):  
Case Report ◽  
Miller Fisher Syndrome ◽  
Fisher Syndrome

scholarly journals Ocular Manifestations of Miller Fisher Syndrome: a Case Report

2021 ◽  
Vol 75 (3) ◽  
pp. 234
Author(s):  
Maja Ravlic ◽  
Lana Knezevic ◽  
Iva Krolo ◽  
Jelena Herman
Keyword(s):  
Case Report ◽  
Miller Fisher Syndrome ◽  
Fisher Syndrome ◽  
Ocular Manifestations

Headache and Ophthalmoparesis: Case Report of an “Atypical” Incomplete Miller-Fisher Syndrome

2018 ◽  
Vol 58 (5) ◽  
pp. 746-749
Author(s):  
David Moreno-Ajona ◽  
Pablo Irimia ◽  
Marta Fernández-Matarrubia
Keyword(s):  
Case Report ◽  
Miller Fisher Syndrome ◽  
Fisher Syndrome

scholarly journals Miller Fisher syndrome and COVID-19: is there a link?

2020 ◽  
Vol 13 (8) ◽  
pp. e236419 ◽  
Author(s):  
Amanda Ray
Keyword(s):  
Case Report ◽  
Severe Acute Respiratory Syndrome ◽  
Respiratory Symptoms ◽  
Miller Fisher Syndrome ◽  
Guillain Barre Syndrome ◽  
The Novel ◽  
Fisher Syndrome ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

Beyond the typical respiratory symptoms and fever associated with severe acute respiratory syndrome, we may still have much to learn about other manifestations of the novel SARS-CoV-2 infection. A patient presented with Guillain-Barré syndrome in China with a concurrent SARS-CoV-2 infection. The following case report looks at a patient presenting with the rare Miller Fisher syndrome, a variant of Guillain-Barré while also testing positive for COVID-19.

scholarly journals Miller Fisher syndrome with early intracranial hypertension and delayed bilateral simultaneous facial nerve palsy: a case report

2019 ◽  
Vol 48 (3) ◽  
pp. 030006051986749
Author(s):  
Yu-Ming Liu ◽  
Yan-Li Chen ◽  
Yan-Hua Deng ◽  
Yan-Ling Liang ◽  
Wei Li ◽  
...  
Keyword(s):  
Case Report ◽  
Facial Nerve ◽  
Intracranial Hypertension ◽  
Nerve Palsy ◽  
Facial Nerve Palsy ◽  
Miller Fisher Syndrome ◽  
Ivig Treatment ◽  
Fisher Syndrome ◽  
Igm Antibodies ◽  
History Of

Miller Fisher syndrome (MFS), a variant of Guillain–Barré syndrome, is characterized by ataxia, areflexia and ophthalmoplegia. This case report describes a 40-year old male that presented with a 3-day history of unsteady walking and numbness on both hands, and a 2-day history of seeing double images and unclear articulation. Lumbar puncture revealed an opening pressure of 260 mm H2O. Plasma serology was positive for anti-ganglioside M1-immunoglobulin M (anti-GM1-IgM) antibodies and negative for anti-ganglioside Q1b (anti-GQ1b) antibodies. The patient was diagnosed with MFS based on the clinical course and neurophysiological findings. On the 4th day of treatment with intravenous immunoglobulin (IVIG), his ataxia and unsteady walking improved, but his bilateral eyeballs were fixed, and over the next few days he developed bilateral peripheral facial paralysis. After 5 days of IVIG treatment, methylprednisolone treatment was offered and the patient's symptoms gradually improved. Early intracranial hypertension and delayed facial nerve palsy may be atypical presentations of MFS. Anti-GM1-IgM antibodies may be the causative antibodies for MFS. If the IVIG therapy does not stop the progression of the disease, the addition of corticosteroid therapy may be effective. However, the relationship between IgM type, anti-GM1 antibody and MFS remains unclear and requires further research.

A Case Report of Atypical Miller-Fisher Syndrome

2012 ◽  
Vol 29 (6) ◽  
pp. 105-110 ◽  
Author(s):  
Seung Min Lee ◽  
Young Seung Ji ◽  
Chang Woo Lee ◽  
Ju Hyun Jeon ◽  
Jung Ho Kim ◽  
...  
Keyword(s):  
Case Report ◽  
Miller Fisher Syndrome ◽  
Fisher Syndrome
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