Effect of oral Anabolic Steroids on BMI, Functional Capacity and Pulmonary Functions of under nourished patients of COPD

2021 ◽  
Vol 15 (11) ◽  
pp. 2930-2931
Author(s):  
Kamran Khan Sumalani ◽  
Uneeba Rehman ◽  
Nousheen Akhter ◽  
Maqbool Ahmed ◽  
Yaya Khan Tonyo ◽  
...  

Aim: Effects of oral anabolic steroids on BMI, functional capacity and pulmonary functions of under nourished patients of COPD Methodology: All COPD patients outside pulmonary rehabilitation program, who met the inclusion criteria, were included. Subjects were given methandienone 5mg BD for six months. Weight, BMI, paO2, peak expiratory flow rate, FEV1 was measured for all subjects initially and six months after treatment. Results: There was significant improvement in weight (p <0.01), BMI (p <0.01), paO2 (p 0.04), peak expiratory flow (p <0.01), six minutes walk distance (p <0.01), CAT (p <0.01) and mMRC scores (p <0.01) after 6 months therapy with anabolic steroid. Conclusion: Treatment with Oral anabolic steroids has a significant effect on BMI and functional capacity of patients with COPD. Keywords: BMI, COPD, oral steroid

2021 ◽  
Vol 9 (1) ◽  
pp. 3724-3729
Author(s):  
Hetal M Mistry ◽  
◽  
Rutuja V Kamble ◽  

Background: In Chronic Obstructive Pulmonary Disease (COPD), as result of dynamic hyperinflation, primary respiratory muscles go into weakness and length tension relationship of muscles is altered. This leads to decreased ability of primary respiratory muscles to generate muscle tension. COPD patients mostly use accessory muscle for breathing and there is lack of facilitation of intercostal muscle and weakness of diaphragm. Few studies are conducted to assess the immediate effect of Chest Proprioceptive Neuromuscular Facilitation (PNF) i.e. intercostal stretch among COPD patients. Therefore, there is need to find out immediate effect of chest PNF- intercostal stretch on respiratory rate (RR), chest expansion, peak expiratory flow rate (PEFR) among patient with COPD. Objective: To find out immediate effect chest PNF on respiratory rate, chest expansion and peak expiratory flow rate. Methodology: Ethical clearance and participant consent was taken. Study design was Qausi experimental study. The 65 subjects were taken by convenient sampling. Intercostal stretch was applied over 2nd and 3rd rib bilaterally for 10 breaths with 1 minute rest with a 10 repetitions and Outcome measures were assessed before and immediately after giving chest PNF. SPSS 16 software was used to analyse the data. The normality of the data was assessed using parametric paired t test. Significance level was set at 0.05 and 95% Confidence Interval. Outcome Measures: Respiratory rate, Chest expansion, Peak expiratory flow rate. Result: Immediate effect of chest PNF showed that there was statistically significant increase in PEFR and chest expansion at three level (P=0.000) and there was statistically significant decrease in RR (P=0.000). Conclusion: There is immediate effect of Chest PNF- intercostal stretch on, Respiratory rate, Chest expansion at three level that is axillary, nipple and xiphisternal and Peak expiratory flow rate. It is an easy to use, less time consuming, easy to understand and cost effective technique. KEY WORDS: Chest PNF, intercostal stretch, COPD.


2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Yi Li ◽  
Hongyu Qian ◽  
Kewei Yu ◽  
Ying Huang

Background. The pulmonary rehabilitation (PR) is beneficial for COPD patients. Due to the poor rate of adherence, we evaluate the factors which will predict the nonadherence of PR. Method. We analyzed the data from a retrospective study of COPD patients who were enrolled to attend the PR program. Patients were classified as the adherence group and the nonadherence group according to completion of over 50% sessions during the 8-week PR program. Demographic characteristics, 6-minute walking distance (6MWD), COPD assessment test (CAT), modified Medical Research Council scale (mMRC), and emotional function were compared between two groups. Univariate and multivariable analyses were performed to determine the factors of poor adherence of PR. Results. Among 418 patients, 170 patients (40.7%) who completed less than 50% sessions of the PR program were categorized as “nonadherence.” Compared to completers, “nonadherence” patients had more cigarette consumption, higher emotional score, less 6MWD, more exacerbation, using nebulizer frequently, and higher rate of smoking at enrollment. On multivariate analysis, more exacerbation frequency (odds ratio (OR) = 1.434, 95% confidence interval (CI): 1.191∼1.796, P=0.046) and smoking at enrollment (OR = 3.349, 95% CI: 1.194∼6.302, P=0.012) were predict factors associated with nonadherence of PR. Conclusion. COPD patients with frequent exacerbation and smoking currently were more likely to be nonadherence during PR.


Lung ◽  
2011 ◽  
Vol 189 (4) ◽  
pp. 279-285 ◽  
Author(s):  
Eanes D. B. Pereira ◽  
Cinthya Sampaio Viana ◽  
Tauily C. E. Taunay ◽  
Penha U. Sales ◽  
Jose W. O. Lima ◽  
...  

Author(s):  
Rejane Agnelo Silva De Castro ◽  
Anderson Alves de Camargo ◽  
Rodolfo de Paula Vieira ◽  
Kátia De Angelis ◽  
Amanda Aparecida de Araujo ◽  
...  

Author(s):  
Paulo José Zimermann Teixeira ◽  
Rafael Machado De Souza ◽  
Álvaro Huber Santos ◽  
Ivo Bohn Jr ◽  
Mateus Schneider ◽  
...  

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