The relationship between harming behavior and substance use profile, and attention deficit hyperactivity disorder symptoms in antisocial personality disorder

Author(s):  
Onur Durmaz
2007 ◽  
Vol 190 (5) ◽  
pp. 410-414 ◽  
Author(s):  
Janine D. Flory ◽  
Jeffrey H. Newcorn ◽  
Carlin Miller ◽  
Seth Harty ◽  
Jeffrey M. Halperin

BackgroundImpulsive aggression in adulthood is associated with disturbances in serotonergic function. In contrast, research examining this association in childhood has yielded inconsistent results.AimsThe current study examined the prospective relationship between serotonergic function measured in childhood and the later emergence of antisocial personality disorder.MethodHormonal response to fenfluramine, an index of serotonergic function, was assessed in 58 children with attention-deficit hyperactivity disorder between 1990 and 1997 when they were aged 7–11 years. Approximately 9 years later these individuals were evaluated for antisocial personality disorder.ResultsLower serotonergic responsivity assessed in childhood predicted the development of antisocial personality disorder (t (56)=2.25, P=0.028).ConclusionsThese results provide a critical link between the child and adult literature on the covariation of impulsive aggression and serotonergic function and suggest a potential explanation for inconsistencies in the childhood literature.


2012 ◽  
Vol 18 (6) ◽  
pp. 436-446 ◽  
Author(s):  
Rakesh Magon ◽  
Ulrich Müller

SummarySubstance use disorders are a frequent comorbidity in adult attention-deficit hyperactivity disorder (ADHD). This review discusses the relationship between adult ADHD and substance use disorder, including use of licit and illicit substances such as nicotine, alcohol, cocaine and cannabis. We discuss treatment studies in this area and provide a treatment algorithm to guide clinicians in the management of adult ADHD comorbid with different forms and severities of substance use disorder.


2018 ◽  
Vol 45 (6) ◽  
pp. 902-917 ◽  
Author(s):  
Matt DeLisi ◽  
Alan J. Drury ◽  
Daniel Caropreso ◽  
Tim Heinrichs ◽  
Katherine N. Tahja ◽  
...  

Antisocial personality disorder (ASPD) requires a childhood diagnosis of conduct disorder (CD); however, some adult offenders are nevertheless diagnosed with ASPD without antecedent CD. The current study used a population of federal correctional clients to examine psychiatric and paraphilic conditions that potentially differentiate these offenders. Attention deficit hyperactivity disorder (ADHD) was associated with a 120% increased likelihood of ASPD with prior CD, but a 75% reduced likelihood of ASPD without CD. Bipolar I disorder was associated with a 328% increased likelihood, frotteurism conferred a 311% increased likelihood, and sexual sadism conferred a 1,033% increased likelihood of ASPD without CD. The findings provide specificity to the heterogeneous ASPD population and help to clarify its equifinality. Implications for correctional practice are that prior psychiatric diagnoses and paraphilic disorders can help to understand the development of serious criminal behavior occurring among adult offenders even if they lacked CD.


2016 ◽  
Vol 74 (12) ◽  
pp. 1003-1007 ◽  
Author(s):  
Carlos Henrique Ferreira Camargo ◽  
Tarcísio Fanha Dornelles ◽  
Karin Barszcz ◽  
Eduardo Antunes Martins

ABSTRACT Objective Attention deficit hyperactivity disorder (ADHD) is characterized by a persistent pattern of inattention or hyperactivity. This study aimed to investigate the relationship between ADHD and drug dependence. Methods The presence and severity of ADHD and substance use were evaluated through questionnaires in 80 adult patients in therapeutic communities. Results No difference in drug use or dependence prevalence between ADHD and non-ADHD patients was found. However, ADHD patients had lower ages on admission (p = 0.004) and at first contact with cocaine (p = 0.033). In ADHD patients, there was a negative correlation between the age at first use of cannabis and the subsequent severity of cannabis use (p = 0.017) and cocaine use (p = 0.033). Conclusions Though there was no difference in prevalence of drug use among groups, results show that ADHD in patients in therapeutic communities may cause different addiction patterns, such as earlier use of cocaine and admission, and a more severe use of cocaine correlated to earlier contact with cannabis.


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