Anti-cancer N-heterocyclic carbene complexes of gold(III), gold(I) and platinum(II) : thiol "switch-on" fluorescent probes, thioredoxin reductase inhibitors and endoplasmic reticulum targeting agents

2015 ◽  
Author(s):  
Taotao Zou
Keyword(s):  
Endoplasmic Reticulum ◽  
Fluorescent Probes ◽  
Thioredoxin Reductase ◽  
Carbene Complexes ◽  
Reductase Inhibitors ◽  
Anti Cancer ◽  
Endoplasmic Reticulum Targeting ◽  
Thiol Switch

scholarly journals Endoplasmic reticulum targeting fluorescent probes to image mobile Zn2+

2019 ◽  
Vol 10 (47) ◽  
pp. 10881-10887 ◽  
Author(s):  
Le Fang ◽  
Giuseppe Trigiante ◽  
Rachel Crespo-Otero ◽  
Chris S. Hawes ◽  
Michael P. Philpott ◽  
...  
Keyword(s):  
Endoplasmic Reticulum ◽  
Fluorescent Probes ◽  
Biological Processes ◽  
Er Targeting ◽  
Endoplasmic Reticulum Targeting

Two endoplasmic reticulum (ER) targeting probes were developed to image mobile Zn2+ to help understand Zn2+ related biological processes in the ER.

Gold(I)N-Heterocyclic Carbene Complexes with Naphthalimide Ligands as Combined Thioredoxin Reductase Inhibitors and DNA Intercalators

ChemMedChem ◽  
2014 ◽  
pp. n/a-n/a ◽  
Author(s):  
Andreas Meyer ◽  
Luciano Oehninger ◽  
Yvonne Geldmacher ◽  
Hamed Alborzinia ◽  
Stefan Wölfl ◽  
...  
Keyword(s):  
Thioredoxin Reductase ◽  
Carbene Complexes ◽  
Dna Intercalators ◽  
Reductase Inhibitors

Gold(III) Complexes Containing N-Heterocyclic Carbene Ligands: Thiol “Switch-on” Fluorescent Probes and Anti-Cancer Agents

2013 ◽  
Vol 125 (10) ◽  
pp. 3002-3005 ◽  
Author(s):  
Taotao Zou ◽  
Ching Tung Lum ◽  
Stephen Sin-Yin Chui ◽  
Chi-Ming Che
Keyword(s):  
Fluorescent Probes ◽  
Carbene Ligands ◽  
Anti Cancer ◽  
Thiol Switch

Gold(III) Complexes Containing N-Heterocyclic Carbene Ligands: Thiol “Switch-on” Fluorescent Probes and Anti-Cancer Agents

2013 ◽  
Vol 52 (10) ◽  
pp. 2930-2933 ◽  
Author(s):  
Taotao Zou ◽  
Ching Tung Lum ◽  
Stephen Sin-Yin Chui ◽  
Chi-Ming Che
Keyword(s):  
Fluorescent Probes ◽  
Carbene Ligands ◽  
Anti Cancer ◽  
Thiol Switch

Abstract 3714: Cytotoxic screening of thioredoxin reductase inhibitors as potential new anti-cancer drugs

2010 ◽  
Author(s):  
Janice M. Santiago ◽  
Sandraliz Espinosa ◽  
Cornelis P. Vlaar ◽  
Marianela Perez-Torres
Keyword(s):  
Thioredoxin Reductase ◽  
Cancer Drugs ◽  
Reductase Inhibitors ◽  
Anti Cancer

Natural thioredoxin reductase inhibitors from Jatropha integerrima

RSC Advances ◽  
2015 ◽  
Vol 5 (58) ◽  
pp. 47235-47243 ◽  
Author(s):  
Jian-Yong Zhu ◽  
Lan-Lan Lou ◽  
Yan-Qiong Guo ◽  
Wei Li ◽  
Yan-Hong Guo ◽  
...  
Keyword(s):  
Thioredoxin Reductase ◽  
Reductase Inhibitors

Nine new diterpenoids were isolated from Jatropha integerrima. The active diterpenoids represent the rare examples of non-aromatic TrxR inhibitors from nature.

Recent Advances in the Development of Thioredoxin Reductase Inhibitors as Anticancer Agents

2012 ◽  
Vol 13 (11) ◽  
pp. 1432-1444 ◽  
Author(s):  
Yang Liu ◽  
Yijing Li ◽  
Shenghui Yu ◽  
Guisen Zhao
Keyword(s):  
Anticancer Agents ◽  
Thioredoxin Reductase ◽  
Reductase Inhibitors ◽  
Recent Advances
Sign in / Sign up

Export Citation Format

Share Document