scholarly journals Prognostic Factors in Cutaneous Squamous Cell Carcinoma: Is Patient Delay in Hospital Visit a Predictor of Survival?

2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Y. Endo ◽  
M. Tanioka ◽  
Y. Miyachi
Keyword(s):  
Squamous Cell Carcinoma ◽  
Prognostic Factors ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Tumour Size ◽  
Japanese Patients ◽  
Cutaneous Squamous Cell Carcinoma ◽  
Hazard Ratio ◽  
Patient Delay ◽  
Hospital Visit

The patient's delay in the visit to a hospital seems to play an important role in prognosis in invasive cutaneous squamous cell carcinoma (SCC). This report explored prognostic factors of cutaneous SCC focusing on patient delay in hospital visit. Data of 117 Japanese patients who were treated for invasive cutaneous SCC in our facility between 2000 and 2010 were used for analysis. A multivariate Cox proportional-hazard modelling revealed that a pair of TNM stage (hazard ratio, 5.0; 95% CI, 1.8 to 13.9) and poorer histological differentiation (hazard ratio, 3.2; 95% CI, 0.93 to 10.3), and a pair of tumour size (hazard ratio, 1.02; 95% CI, 1.004 to 1.04) and rapid growth (hazard ratio, 8.25; 95% CI, 1.29 to 52.7) were a prognostic factor whereas patient delay in hospital visit was not. However, patient delay in hospital visit was correlated with larger tumour size.

scholarly journals Metastatic cutaneous squamous cell carcinoma of the head and neck: Characteristics of the primary and poor prognostic factors

2012 ◽  
Vol 10 (8) ◽  
pp. S5
Author(s):  
David Walker ◽  
Rajeev Mathew ◽  
Tatiana Gutierrez ◽  
Reza Nouraei ◽  
Patrick McCabe ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Prognostic Factors ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Cutaneous Squamous Cell Carcinoma

Cutaneous squamous cell carcinoma metastatic to the axilla and groin: Outcomes and prognostic factors

2021 ◽  
Author(s):  
Nicholas W Bucknell ◽  
David E Gyorki ◽  
Mathias Bressel ◽  
Vanessa Estall ◽  
Angela Webb ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Prognostic Factors ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Cutaneous Squamous Cell Carcinoma

Advanced cutaneous squamous cell carcinoma of the trunk and extremity: Analysis of prognostic factors

1997 ◽  
Vol 64 (3) ◽  
pp. 212-217 ◽  
Author(s):  
James H. North ◽  
James E. Spellman ◽  
Deborah Driscoll ◽  
Augustine Velez ◽  
William G. Kraybill ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Prognostic Factors ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Cutaneous Squamous Cell Carcinoma

scholarly journals Real-world Treatment Patterns and Outcomes with Systemic Therapies in Unresectable Locally Advanced and Metastatic Cutaneous Squamous Cell Carcinoma in Germany

2021 ◽  
Author(s):  
Felix Kramb ◽  
Christoph Doerfer ◽  
Andreas Meiwes ◽  
Karthik Ramakrishnan ◽  
Thomas Eigentler ◽  
...  
Keyword(s):  
Overall Survival ◽  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Systemic Treatment ◽  
Locally Advanced ◽  
Progression Free Survival ◽  
Cutaneous Squamous Cell Carcinoma ◽  
Hazard Ratio ◽  
Free Survival

Advanced cutaneous squamous cell carcinoma is a challenge to treat. Conventional systemic treatment options include chemotherapy and epidermal growth factor receptor-inhibitors. The aim of this study was to assess clinical outcomes with systemic treatments in advanced cutaneous squamous cell carcinoma. Patients receiving systemic treatment at the Tübingen Dermato-Oncology centre between 2007 and 2017 were identified (n = 59). Median age was 76 years (interquartile range (IQR) 71–80 years), 83.1% of patients were male, 72.9% had metastatic cutaneous squamous cell carcinoma, and 27.1% had unresectable locally advanced cutaneous squamous cell carcinoma. During median follow-up of 52 weeks (IQR 27–97 weeks), overall response rate was 14.3%, and disease control rate was 53.6%. Median progression-free survival was 15 weeks (IQR 8–42 weeks), and median overall survival was 52 weeks (IQR 27–97 weeks). Patients receiving chemoradiation vs chemo­therapy alone showed better overall survival (hazard ratio 0.41, p = 0.014,) and progression-free survival (hazard ratio 0.42, p = 0.009); no differences were observed for metastatic cutaneous squamous cell carcinoma vs locally advanced cutaneous squamous cell carcinoma patients. Although chemotherapy and/or cetuximab showed limited outcomes in advanced cutaneous squamous cell carcinoma, such therapy may still be an option when anti-PD-1 treatment is contraindicated.

scholarly journals Prognostic factors for metastatic cutaneous squamous cell carcinoma of the parotid

2013 ◽  
Vol 42 (1) ◽  
Author(s):  
Fawaz M Makki ◽  
Adrian I Mendez ◽  
S Mark Taylor ◽  
Jonathan Trites ◽  
Martin Bullock ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Prognostic Factors ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Cutaneous Squamous Cell Carcinoma
Sign in / Sign up

Export Citation Format

Share Document