Methylmercury poisoning in St Bartholomew’s Hospital and Dr. G.N. Edwards

2018 ◽  
Vol 35 (04) ◽  
pp. 100-103
Author(s):  
Nobuo Ishihara

1975 ◽  
Vol 9 (2) ◽  
pp. 128-134 ◽  
Author(s):  
Shamshad H. Gilani


PEDIATRICS ◽  
1977 ◽  
Vol 59 (1) ◽  
pp. 138-138
Author(s):  
Mutsuhiro Furuta

I would like to make a few observations concerning the article by Amin-Zaki et al.1 First, I challenge the wisdom of using "intrauterine" in the title. The article does not give conclusive evidence that the poisoning was actually intrauterine. It gives no data on blood examinations of the infants at birth, which is of utmost importance. Without these data, can one say it is "congenital" methylmercury poisoning? Furthermore, there is no discussion of the method of transmission of the methylmercury from mother to fetus or unchallengable proof that this is true.



1986 ◽  
Vol 64 (3) ◽  
pp. 442-448 ◽  
Author(s):  
E. Buncel ◽  
R. Kumar ◽  
A. R. Norris

A number of methylmercurated complexes of 6-mercaptopurine riboside and 2-amino-6-mercaptopurine riboside (6-MNucH2) containing S-bound CH3Hg(II) in neutral and cationic complexes (as in [CH3Hg(6-MNucH)] and [CH3Hg(6-MNucH2)]NO3), S- and N-bound CH3Hg(II) (as in [(CH3Hg)2(6-MNucH)]NO3), and S-, N-, C-bound CH3Hg(II) (as in [(CH3Hg)3(6-MNuc)]NO3) have been prepared in aqueous solution at appropriate pH and mole ratios of the constituents. The complexes were characterized by means of 1H and 13C nmr and ir spectroscopy and elemental analysis. Formation of C-bound methylmercurated species extends our previous results obtained with xanthosine, inosine, and imidazole derivatives, and substantiates our proposal that activation through electrophilic coordination at N(7) is a requirement for C(8)—H abstraction. 2J(1H–199Hg) coupling constants, measured in (CD3)2SO for a number of CH3Hg(II) complexes of N-, S-, and C-donor heterocyclic ligands, including the 6-mercaptopurine riboside of the present study, correlate well with the 1J(13C–199Hg) coupling constants, according to 1J = 8.4602J − 155.6. The significance of this correlation in terms of the strength of the Hg–ligand bond is considered. The results could provide insight into the apparent selectivity of binding of CH3Hg(II) by bio-ligands, as well as in the design of chemotherapeutic agents for the treatment of methylmercury poisoning.



2020 ◽  
Author(s):  
Michał Rakociński ◽  
Leszek Marynowski ◽  
Agnieszka Pisarzowska ◽  
Jacek Bełdowski ◽  
Grzegorz Siedlewicz ◽  
...  


1975 ◽  
Vol 33 (1) ◽  
pp. 27-37 ◽  
Author(s):  
Clas Fehling ◽  
Mohammed Abdulla ◽  
Arne Brun ◽  
Michael Dictor ◽  
Andrejs Schütz ◽  
...  


1994 ◽  
Vol 60 (3) ◽  
pp. 188-196 ◽  
Author(s):  
Simon Yee ◽  
Ben H. Choi


Author(s):  
Alessandra A. Dos Santos ◽  
Louis W. Chang ◽  
Grace Liejun Guo ◽  
Michael Aschner




1980 ◽  
Vol 56 (651) ◽  
pp. 1-10 ◽  
Author(s):  
F. Bakir ◽  
H. Rustam ◽  
S. Tikriti ◽  
S. F. Al-Damluji ◽  
H. Shihristani


2005 ◽  
Vol 27 (4) ◽  
pp. 643-653 ◽  
Author(s):  
Tadashi Ninomiya ◽  
Keiko Imamura ◽  
Misako Kuwahata ◽  
Michiaki Kindaichi ◽  
Mari Susa ◽  
...  


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