scholarly journals Melatonin decreases eye pressure in depressive patients with normal intraocular pressure

Author(s):  
Gokhan Ozdemir ◽  
Ebru Findikli
Author(s):  
Eniko T. Enikov ◽  
Péter P. Polyvás ◽  
Gholam Peyman ◽  
Sean Mccafferty

This article presents the early results from a 10-person human subject study evaluating the accuracy of a novel method of indirect estimation of intraocular pressure using tactile sensors. Manual digital palpation tonometery is an old method used to estimate the eye pressure through palpation with ones fingers. Based on this concept, we present an instrumented measurement method, where multiple tactile stiffness sensors are used to infer the intraocular pressure of the eye. The method is validated using experimental data gathered from human subjects with eye pressures from 15 to 22 mmHg and determined by Goldman applanation tonometry (GAT). Bland-Altman plots comparing the GAT measurements and the proposed through-the-eye-lid tonometry indicate a statistical error of 5.16 mmHg, within the 95% confidence interval, which compares favorably with the FDA-mandated error bound of 5 mmHg. Details on the unit operation and data filtering are also presented. Due to its indirect and non-invasive nature, the proposed new tactile tonometry method can be applied at home as a self-administered home tonometer for management of glaucoma.


Ophthalmology ◽  
1993 ◽  
Vol 100 (9) ◽  
pp. 1312-1317 ◽  
Author(s):  
Albert Alm ◽  
Jörgen Villumsen ◽  
Per Törnquist ◽  
Agneta Mandahl ◽  
Juhani Airaksinen ◽  
...  

2018 ◽  
Vol 2018 ◽  
pp. 1-13 ◽  
Author(s):  
Robert Koprowski ◽  
Sławomir Wilczyński

Introduction. The paper presents a commentary on the method of analysis of corneal vibrations occurring during eye pressure measurements with air-puff tonometers, for example, Corvis. The presented definition and measurement method allow for the analysis of image sequences of eye responses—cornea deformation. In particular, the outer corneal contour and sclera fragments are analysed, and 3D reconstruction is performed. Methods. On this basis, well-known parameters such as eyeball reaction or corneal response are determined. The next steps of analysis allow for automatic and reproducible separation of four different corneal vibrations. These vibrations are associated with (1) the location of the maximum of cornea deformation; (2) the cutoff area measured in relation to the cornea in a steady state; (3) the maximum of peaks occurring between applanations; and (4) the other characteristic points of the corneal contour. Results. The results obtained enable (1) automatic determination of the amplitude of vibrations; (2) determination of the frequency of vibrations; and (3) determination of the correlation between the selected types of vibrations. Conclusions. These are diagnostic features that can be directly applied clinically for new and archived data.


2016 ◽  
Vol 24 (4) ◽  
pp. 169-179 ◽  
Author(s):  
Lena K. Jooß ◽  
Lena V. Krämer ◽  
Mary Wyman
Keyword(s):  

Abstract. Studies of exercise in depression have not focused on persons already engaging in exercise. The current study aimed to provide an in-depth examination of exercise in depressive persons. In all, 62 depressive outpatients were compared with 62 parallelized nondepressive controls on various aspects of self-reported exercise (total amount, frequency, duration, intensity, type). Of the depressive participants, 52 % and of the nondepressive participants 76 % reported engaging in exercise. Compared with nondepressive exercisers, depressive exercisers exercised less (average total amount of M = 1.7 vs. M = 2.7 hr/week, including all intensity levels), were exercising less frequently (M = 1.7 vs. M = 2.6 sessions/week), and were engaged in fewer different exercise types (M = 1.4 vs. M = 2.0). Groups did not differ in intensity (M = 6.1 vs. 6.2 METs) or duration of exercise sessions (M = 1.1 hr). Exercisers with depression engage in exercise at reduced levels compared with nondepressive exercisers. Interventions to increase exercise in depressive patients should focus on raising the frequency of exercise sessions rather than the duration or intensity.


2020 ◽  
Author(s):  
T Kroll ◽  
M Klingebiel ◽  
M Grözinger ◽  
M Matusch ◽  
A Novakovic ◽  
...  

Author(s):  
E. N. Simakova ◽  
O. V. Stenkova

Introduction. Glaucoma is one of the most significant eye diseases. It is often diagnosed, not always amenable to therapy, and can lead to a complete loss of visual functions. In recent years, the method of osteopathic correction has become widespread as one of the effective methods of treatment and rehabilitation of patients with pathologies of various body systems. In the pathogenesis of glaucoma, it is customary to distinguish a dystrophic concept, which considers primary open-angle glaucoma as a result of dystrophic changes in the connective tissue, as well as in the endothelial lining of the trabeculae and Schlemm′s canal, especially destructive changes in mitochondria and the alteration of their functional activity. A vascular concept is also distinguished. According to this concept, the central link in the pathogenesis of glaucoma is circulatory disorder in the ciliary vessels, ocular artery, and major vessels of the head and neck, it can be assumed that osteopathic correction in the treatment of patients with open-angle glaucoma will be pathogenetically substantiated and will have a positive effect on intraocular pressure and trophicity of the optic nerve. The goal of research — to study the influence of in osteopathic correction on the nature of unoperated glaucoma (stage IIA) and to substantiate the possibility of using osteopathic correction in the complex treatment of patients with this pathology.Materials and methods. A prospective controlled randomized study was conducted at 52 city polyclinics, branch 3, Moscow, from January 2018 to January 2019. 40 patients (70 eyes) aged 50 to 75 years with primary open-angle glaucoma IIA stage were examined. At this stage of the disease, patients most often seek medical care and the issue of conservative management is primarily considered. All patients were divided into two groups of 20 people: the main group and the control group. The treatment in the main group included hypotensive drug therapy and osteopathic correction. Patients of the control group received only drug therapy. All patients underwent ophthalmic (visometry, tonometry, perimetry) and osteopathic examination twice: before the treatment and after 3 months.Results. For patients with primary open-angle IIA non-operated glaucoma, regional (most often regions of the head, neck, dura mater) and local (abdominal diaphragm, iliac bones, hip and knee joints) somatic dysfunctions were the most typical. In the main group a statistically significant decrease in the frequency and severity of dysfunctions at all levels was stated. Also, in patients receiving osteopathic correction, a significant decrease in the level of intraocular pressure and perimetric indices was noted. In patients of the control group, no reliable changes in these indicators were obtained.Conclusion. The results obtained indicate that osteopathic correction is clinically effective in the complex treatment of patients with primary open-angle II A glaucoma.


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