scholarly journals Role of frozen section analysis of testicular/paratesticular fibrous pseudotumours: a five-case experience

2013 ◽  
Vol 5 (4) ◽  
pp. 47
Author(s):  
Jennifer Gordetsky ◽  
Jennifer Findeis-Hosey ◽  
Erdal Erturk ◽  
Edward M. Messing ◽  
Jorge L. Yao ◽  
...  

Background: Fibrous pseudotumours of the testicular and paratesticulartissues are fibroinflammatory reactive lesions that canclinically mimic neoplasms. Very little is known about the role offrozen section analysis (FSA) for these lesions in terms of intraoperativesurgical management.Methods: We recently experienced 5 patients with testicular/paratesticularfibrous pseudotumours in whom frozen sections wereused to demonstrate its non-neoplastic nature prior to the decisionfor radical surgery.Results: In 2 cases, FSA resulted in testicular-sparing surgery. Incontrast, the remaining 3 cases ultimately underwent radical orchiectomy,due to questionable viability of the testicle involved byinflammatory/infiltrative lesions and in 1 case a slight possibilityof lymphoproliferative malignancy.Conclusion: Urologists should be aware of this entity and its grossfeatures, such as firm masses and diffuse fibrous proliferation encasingthe testicle to help determine intraoperative management. Inselect cases, intraoperative FSA is helpful in obviating radicalorchiectomy.

2012 ◽  
Vol 187 (4S) ◽  
Author(s):  
Yasuhiro Kakiuchi ◽  
Bonnie Choy ◽  
Jennifer Gordetsky ◽  
Guan Wu ◽  
Hani Rashid ◽  
...  

1998 ◽  
Vol 4 (2) ◽  
pp. 133-133 ◽  
Author(s):  
Sharon Weber ◽  
F. Kristian Storm ◽  
Judith Stitt ◽  
David M. Mahvi

HPB ◽  
2018 ◽  
Vol 20 ◽  
pp. S582-S583
Author(s):  
S.R.V. Gunturi ◽  
V. Thumma ◽  
N. Kunduru ◽  
J.R. Bathalapalli ◽  
G.R. Gondu ◽  
...  

2020 ◽  
Vol 9_2020 ◽  
pp. 120-128
Author(s):  
Nosova Yu.V. Nosova ◽  
Solopova A.E. Solopova ◽  
Asaturova A.V. Asaturova ◽  
Tregubova A.V. Tregubova ◽  
Kometova V.V. Kometova ◽  
...  

2001 ◽  
Vol 8 (2) ◽  
pp. 92-100 ◽  
Author(s):  
Ari D. Brooks ◽  
Ashok R. Shaha ◽  
Wilson DuMornay ◽  
Andrew G. Huvos ◽  
Maureen Zakowski ◽  
...  

Author(s):  
Marwan Odeh ◽  
Ayat Qasoum ◽  
Rene Tendler ◽  
Mohamad Kais ◽  
Rola Khamise Farah ◽  
...  

Objective Frozen section examination is a rapid method for identifying products of conception in endometrial curetting, yet its accuracy is inconclusive. The purposes of this study is to determine the accuracy of frozen section analysis of endometrial curetting in pregnancies of unknown location, and to verify the relation of β-human chorionic gonadotrophin (hCG) level and endometrial thickness to the assessed accuracy. Methods We reviewed data from January 2009 to December 2014 of diagnostic curettages from women with suspected ectopic pregnancies sent for frozen section examination at a medical center. A frozen section diagnosis was considered accurate if it concurred with the final pathologic diagnosis. Results Of 106 frozen section studies, the diagnosis was accurate in 94 (88.7%). Of 79 specimens interpreted as negative on frozen sections (no products of conception noted), 9 (11.4%) were positive on final pathologic review. Three of the 27 (11.1%) specimens interpreted as positive by a frozen section failed to demonstrate products of conception on a final pathologic section. The sensitivity of frozen sections in the diagnosis of ectopic pregnancy was 72.7%, specificity 95.9%, positive predictive value 88.9%, negative predictive value 88.6%, and accuracy 88.6%. A statically significant correlation was found between β-hCG level and high accuracy of the frozen section technique (p < 0.001). No correlation was found between endometrial thickness and the accuracy of the frozen section technique. Conclusion The accuracy of frozen section examination was high and was found to correlate with β-hCG level, but not with endometrial thickness.


2005 ◽  
Vol 15 (2) ◽  
pp. 192-202 ◽  
Author(s):  
L. R. Medeiros ◽  
D. D. Rosa ◽  
M. I. Edelweiss ◽  
A. T. Stein ◽  
M. C. Bozzetti ◽  
...  

A quantitative systematic review was performed to estimate the diagnostic accuracy of frozen sections in ovarian tumors. Studies that compared frozen sections and paraffin sections within subjects for diagnosis of ovarian tumors were included. Fourteen primary studies were analyzed, which included 3 659 women. For benign ovarian vs borderline/malignant tumor cases, the occurrence of a positive frozen-section result for benignity (pooled likelihood ratio [LR], 8.7; 95% confidence interval [CI], 7.3–10.4) and posttest probability for benign diagnosis was 95% (95% CI, 94–96%). A positive frozen-section result for malignant vs benign diagnosis (pooled LR, 303; 95% CI, 101–605) increased the probability of ovarian cancer to 98% (95% CI, 97–99%). In borderline vs benign ovarian tumor cases, a positive frozen-section result (pooled LR, 69; 95% CI, 45–106) increased the probability of borderline tumors to 79% (95% CI, 71–85%). In borderline vs malignant ovarian tumor cases, a positive frozen-section result (pooled LR, 18; 95% CI, 13–26) increased the probability of borderline tumors to 51% (95% CI, 42–60%). We conclude that diagnostic accuracy rates for frozen-section analysis is high for malignant and benign ovarian tumors, but the accuracy rates in borderline tumors remain relatively low.


2020 ◽  
Vol 1 (1) ◽  
Author(s):  
Seyed Mirsattari ◽  
Fraser W. Saunders

To determine the role of intraoperative frozen sections (FSs) in the management of patients with central nervous system (CNS) lesions, 60 consecutive intraoperative clinical diagnoses of CNS lesions were presented and compared with concomitantly obtained FS diagnoses. Clinical diagnoses were established byhistory, physical examination, imaging techniques, and gross appearance of the abnormal tissue in situ. Tissue samples were obtained intraoperatively and processed for FS diagnoses. The findings of the FS diagnoses were reported to the operating room and compared with the clinical diagnoses. The remainingbiopsy samples were used to prepare paraffin-embedded tissue sections from which the definitive diagnoses were made. Comparison of the clinical and FS diagnoses, using paraffin-embedded tissue as the true diagnosis, shows that FS diagnosis has a limited contribution to intraoperative patient management by the neurosurgeon. The rate of diagnostic failures between the two techniques was very similar; clinical diagnoses and FSs were misinterpreted in 12 and 11 of the 60 cases, respectively. Compared to a clinical diagnosis, the intraoperative FS technique provided no significant improvement in diagnosis and management; it altered the intraoperative management of the patients in 2 of 60 cases.


Sign in / Sign up

Export Citation Format

Share Document