scholarly journals The prevalence of nonalcoholic liver steatosis in patients with type 2 diabetes mellitus in the Czech Republic

2015 ◽  
Vol 159 (3) ◽  
pp. 442-448 ◽  
Author(s):  
Karel Dvorak ◽  
Radvan Hainer ◽  
Jaromir Petrtyl ◽  
Miroslav Zeman ◽  
Tomas Vareka ◽  
...  

2019 ◽  
Vol 10 (2) ◽  
pp. 493-508 ◽  
Author(s):  
Johannes Pöhlmann ◽  
Monika Russel-Szymczyk ◽  
Pavel Holík ◽  
Karel Rychna ◽  
Barnaby Hunt








2020 ◽  
Vol 66 (5) ◽  
pp. e33-e37
Author(s):  
Pavel Hroboň ◽  
Magdalena Škodová ◽  
Petra Kučová ◽  
Jana Votápková




2015 ◽  
Vol 27 (12) ◽  
pp. 1386-1391 ◽  
Author(s):  
Alessandra Cosma ◽  
Diego Cecchet ◽  
Silvia Gaiani ◽  
Anna Coracina ◽  
Paolo Pellizzari ◽  
...  


2021 ◽  
Vol 84 (4) ◽  
pp. 541-547
Author(s):  
T Van Nieuwenhove ◽  
G Rasschaert ◽  
A Kharagjitsingh ◽  
B Keymeulen ◽  
H Reynaert ◽  
...  

Background and study aim: Disorders of the gut-brain axis (DGBI) and metabolic dysfunction-associated liver disease (MAFLD) are frequently diagnosed and exhibit pathophysiological similarities. This study aimed to estimate the prevalence of DGBI in type 2 diabetes mellitus (T2DM) patients with MAFLD. Patients and methods: In this single center, observational study, in adults with T2DM demographics, diabetes-related parameters and liver tests were recorded. MAFLD was defined by the presence of hepatic steatosis on imaging. Functional dyspepsia (FD) and irritable bowel syndrome (IBS) were diagnosed based on Rome IV criteria. Quality of life (QOL), anxiety levels and depression levels were documented by validated questionnaires. Results: We included 77 patients, 44 with and 33 without steatosis. There were no significant differences in age, body mass index (BMI), waist circumference, HbA1c levels or metformin use between groups. IBS was significantly more prevalent in the liver steatosis group (9/44 vs. 2/33, p = .037), while a similar trend was observed for FD (9/35 vs. 2/31, p = .103). No differences were found in anxiety, depression and overall QOL. However, QOL subscales for health worry, food avoidance and social reaction were significantly higher in the liver steatosis group. Conclusions: In otherwise comparable T2DM patients, DGBI, and especially IBS, are more prevalent in the presence of MAFLD. This difference could not be attributed to increased levels of anxiety or depression. Future research should target the underlying pathophysiological mechanisms. (Acta gastroenterol. belg., 2021, 84, 541-547).



2014 ◽  
Vol 17 (7) ◽  
pp. A342-A343
Author(s):  
A. Troelsgaard ◽  
A. Pitcher ◽  
Š. Veselá ◽  
E. Lovato ◽  
M. Hemels


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