False-Positive Whole-Body I-131 Scan In Thyroid Carcinoma Caused By Gastrooesophageal Reflux Disease

10.5580/1b18 ◽  
2009 ◽  
Vol 5 (1) ◽  
2013 ◽  
Vol 74 (3) ◽  
pp. 221-230 ◽  
Author(s):  
Leckzinscka Buton ◽  
Olivier Morel ◽  
Patricia Gault ◽  
Frédéric Illouz ◽  
Patrice Rodien ◽  
...  

2009 ◽  
Vol 53 (7) ◽  
pp. 874-879 ◽  
Author(s):  
Maria Eduarda Mello ◽  
Rodrigo C. Flamini ◽  
Rossana Corbo ◽  
Marcelo Mamede

The radioactive iodine has been used with great value as a diagnostic and therapeutic method in patients with differentiated thyroid carcinoma previously submitted to total thyroidectomy. False-positive whole-body scans may occur due to misinterpretation of the physiologic distribution of the radioisotope or lack of knowledge on the existence of other pathologies that could eventually present radioiodine uptake. Thymic uptake is an uncommon cause of false-positive whole-body scan, and the mechanism through which it occurs is not completely understood. The present paper reports five cases of patients with differentiated thyroid cancer who presented a mediastinum uptake of radioiodine in a whole-body scan during follow-up. The patients had either histological or radiological confirmation of the presence of residual thymus gland. It is very important to know about the possibility of iodine uptake by the thymus in order to avoid unnecessary treatment, such as surgery or radioiodine therapy.


2019 ◽  
Vol 5 (5) ◽  
pp. e311-e315
Author(s):  
Nevena Manevska ◽  
Sinisa Stojanoski ◽  
Tanja Makazlieva ◽  
Anamarija Jovanovska

Objective: Radioiodine ablation with iodine-131 is a standard therapeutic procedure for patients diagnosed with differentiated thyroid carcinoma (DTC). We present a contamination artifact on whole-body scan (WBS), after radioiodine ablation due to papillary thyroid carcinoma. The hybrid imaging resolved the question of metastasis versus contamination. Methods: In the case of 35-year-old female patient we used a General Electric hybrid gamma camera with a high-energy-general-purpose collimator for performing WBS, and single photon emission computed tomography combined with low dose computed tomography (SPECT/CT) for the detection of any residual thyroid tissue or meta-static disease and at the same time ablation and treatment of any confirmed metastasis. Results: A thyroid scan showed activity in the remnant thyroid tissue of the right lobe, but also laterally in the calvaria (left temporal region). The patient's neck ultra-sound and thyroglobulin level were not in favor of metastasis. A false positive finding due to hair coloring was concluded with SPECT/CT hybrid imaging. Conclusion: SPECT/CT scan can contribute to establishing a final diagnosis in patients being evaluated for atypical locations of radioactive iodine accumulation after ablative doses of radioactive iodine, distinguishing between metastases from DTC and false positive accumulations or artifacts.


1997 ◽  
Vol 22 (6) ◽  
pp. 380-384 ◽  
Author(s):  
MASSIMO SALVATORI ◽  
IDA SALETNICH ◽  
VITTORIA RUFINI ◽  
LUIGI TRONCONE

2000 ◽  
Vol 25 (2) ◽  
pp. 137 ◽  
Author(s):  
JUAN JOSE DUQUE ◽  
MARIA BEGOÑA MIGUEL ◽  
ENRIQUE RUIZ ◽  
LUIS CASTILLO ◽  
MANUEL CLAVER ◽  
...  

2004 ◽  
Vol 29 (3) ◽  
pp. 164-166 ◽  
Author(s):  
Seng Chuan Ong ◽  
David Ng Chee Eng ◽  
Felix X. Sundram ◽  
Ling Ling Chan

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