Evaluation of benign tumors of large salivary glands according to the new classification of the European Salivary Gland Society

2021 ◽  
Vol 75 (2) ◽  
Author(s):  
Izabela Olejniczak ◽  
Agata Leduchowska ◽  
Zbigniew Kozłowski ◽  
Wioletta Pietruszewska
Keyword(s):  
Parotid Gland ◽  
Head And Neck ◽  
Salivary Glands ◽  
Benign Tumors ◽  
Histopathological Diagnosis ◽  
Gland Tumor ◽  
New Classification ◽  
Superficial Parotidectomy ◽  
Parotid Gland Tumor ◽  
Imaging Results

Introduction: Tumors of large salivary glands constitute about 2-3% of all head and neck tumors. Their incidence is statistically greater in males than in females, with the first symptoms usually appearing between the 4th and 7th decade of life. Material and methods: The aim of the study was to assess the usefulness of the new classification proposed by ESGS in comparison with the divisions of procedures previously valid in the literature, making a retrospective analysis of patients operated due to benign tumors of large salivary glands in the Department of Otolaryngology, Head and Neck Oncology of the Medical University of Lodz in 2012-2020. The retrospective examination was based on the material consisting of: surgical protocols, histopathological results, imaging results and clinical observations. Results: The material includes 283 patients (141 women and 142 men): 249 patients with parotid gland tumor and 34 patients with submandibular gland tumor. The most common histopathological diagnosis was pleomorphic adenoma, which was found in 105 patients (42.17%) and adenolymphoma diagnosed in 94 patients (37.75%). The most common type of surgery was superficial parotidectomy including total superficial parotidectomy in 86 patients (34.54%) and partial superficial parotidectomy in 49 cases (19.68%). Then, according to the frequency of surgery, extracapsular tumor dissection (ECD) was performed (91 patients - 36.55%). According to the ESGS classification, in most cases parotidectomy I, II (37.34% of all parotidectomies) and parotidectomy II (28.49%) were performed. In case of ECD, all tumors were located at level II. Conclusions: In summary, the new classification is aimed at unifying, but also simplifying the current nomenclature, reducing the existing nomenclature errors. By determining the exact location and extent of the tumor within the parotid gland, it facilitates postoperative monitoring of patients by ENT doctors and those of other specialties. Key words: ESGS classification, parotid gland, parotidectomy, extracapsular tumor dissection

scholarly journals Superficial Parotidectomy by Retrograde Facial Nerve Dissection

2017 ◽  
Vol 10 (1) ◽  
pp. 25-27
Author(s):  
Narendra Vikram Gurung ◽  
D Shrestha ◽  
A Acharya ◽  
A Gurung ◽  
S Shrestha ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Facial Nerve ◽  
Head And Neck Neoplasms ◽  
Complication Rate ◽  
Gland Tumor ◽  
Superficial Parotidectomy ◽  
Salivary Fistula ◽  
Parotid Tumors ◽  
Parotid Gland Tumor

Introduction: Tumors of the salivary gland are relatively uncommon and represent less than two percentage of all head and neck neoplasms. Parotid gland tumor comprises 85% of the salivary gland tumors of which 80% are being benign. Superficial parotidectomy is the commonest procedure done for parotid tumors which can be performed by either anteretrograde or retrograde facial nerve dissection technique.Methods: Outcome of 60 patients after superficial parotidectomy with retrograde facial nerve dissection has been studied.Results: Total of 60 patients had been studied. Complications like facial nerve weakness, Freys syndrome, salivary fistula, and wound infection were taken into account. Among them, 13.33% patients developed temporary facial nerve weakness, followed by temporary salivary fistula, 1.6%. None of the patients developed any severe complication.Conclusion: Superficial parotidectomy by retrograde facial nerve dissection is an easy technique to carry out with low complication rate and without compromising surgical outcome.Journal of Gandaki Medical CollegeVol. 10, No. 1, 2017, page: 25-27

Linfoma no Hodgkin tipo MALT de la glándula parótida

2020 ◽  
Vol 63 (3) ◽  
pp. 19-22
Author(s):  
Cinthia Karina Vidal Beckers ◽  
Deishi Myreya Vallejo Rodríguez ◽  
Mario Alberto García Pérez ◽  
Miguel Ángel Vázquez Zamora
Keyword(s):  
Parotid Gland ◽  
Key Words ◽  
Salivary Glands ◽  
Malt Lymphoma ◽  
Lymphoid Tissue ◽  
Slow Growth ◽  
Rare Entity ◽  
Gland Tumor ◽  
Parotid Gland Tumor ◽  
Hodgkin's Lymphomas

Lymphomas of the salivary glands are a rare entity with a rare incidence. They are more commonly found on the parotid gland, followed by the submandibular and sublingual glands. The majority of parotid lymphomas are non-Hodgkin’s lymphomas and are considered to be derived from mucosal-associated lymphoid tissue (MALT). Reports of these cases are scarce and often misdiagnosed since: their manifestation is relatively benign, they have a localized behavior, a slow growth and the evolution takes several years. Key words: Type MALT lymphoma; parotid gland tumor

scholarly journals Oncocytoma of the Parotid Gland with Facial Nerve Paralysis

2018 ◽  
Vol 2018 ◽  
pp. 1-4
Author(s):  
Seijiro Hamada ◽  
Keishi Fujiwara ◽  
Hiromitsu Hatakeyama ◽  
Akihiro Homma
Keyword(s):  
Parotid Gland ◽  
Facial Nerve ◽  
Malignant Tumor ◽  
Case Reports ◽  
Benign Tumors ◽  
Facial Nerve Paralysis ◽  
Gland Tumor ◽  
Nerve Paralysis ◽  
Parotid Gland Tumor

Parotid gland tumor with facial nerve paralysis is strongly suggestive of a malignant tumor. However, several case reports have documented benign tumors of the parotid gland with facial nerve paralysis. Here, we report a case of oncocytoma of the parotid gland with facial nerve paralysis. A 61-year-old male presented with pain in his right parotid gland. Physical examination demonstrated the presence of a right parotid gland tumor and ipsilateral facial nerve paralysis of House–Brackmann (HB) grade III. Due to the facial nerve paralysis, a malignant tumor of the parotid gland was suspected and right parotidectomy was performed. Oncocytoma was confirmed histopathologically. The facial nerve paralysis was resolved 2 months after surgery. During the follow-up period (one and a half years), no recurrence was observed. As the tumor showed a distinctive dumbbell shape and increased somewhat due to inflammation (i.e., infection), the facial nerve was pinched by the enlarged tumor. Ischemia and strangulation of the nerve were considered to be the cause of the facial nerve paralysis associated with the benign tumor in this case.

scholarly journals Warthin’s Tumour in Accessory Parotid Gland

2015 ◽  
Vol 20 (1) ◽  
pp. 43-45
Author(s):  
Kazi Atikuzzaman
Keyword(s):  
Parotid Gland ◽  
Facial Nerve ◽  
Masseter Muscle ◽  
Surgical Excision ◽  
Histopathological Diagnosis ◽  
Gland Tumor ◽  
Parotid Gland Tumor ◽  
Cadaver Studies ◽  
Accessory Parotid Gland ◽  
Gland Tumour

The accessory parotid gland is salivary tissue separated from the main parotid gland and lying on masseter muscle. The accessory parotid gland is not rare, according to cadaver studies, but neoplasm in the accessory parotid gland is rare. Surgical excision is the treatment of choice for the accessory parotid gland tumour. It is important to identify the buccal branch of the facial nerve to avoid injury to the facial nerve. Herein we describe a case of accessory parotid gland tumor in a 30 years old lady. Histopathological diagnosis was Warthin’s tumour which is very rare in female. DOI: http://dx.doi.org/10.3329/bjo.v20i1.22017 Bangladesh J Otorhinolaryngol; April 2014; 20(1): 43-45

scholarly journals Giant Cell Carcinosarcoma of the Parotid Gland With a PLAG 1 Translocation in Association With a Pleomorphic Adenoma With HMGA2 Translocation

2020 ◽  
Vol 154 (6) ◽  
pp. 811-815
Author(s):  
Levon Katsakhyan ◽  
Virginia A LiVolsi ◽  
Ara A Chalian ◽  
Paul J Zhang
Keyword(s):  
Salivary Gland ◽  
In Situ Hybridization ◽  
Parotid Gland ◽  
Giant Cell ◽  
Pleomorphic Adenoma ◽  
De Novo ◽  
Sarcomatous Component ◽  
Gland Tumor ◽  
Parotid Gland Tumor

Abstract Objectives Carcinosarcomas of the salivary gland are rare neoplasms and have been described arising de novo or in association with pleomorphic adenoma (PA). PLAG1 and HMGA2 translocations are known to occur in PAs and carcinomas ex PA but are mutually exclusive. Methods We report a case of a carcinosarcoma in the parotid gland of a 77-year-old man with unusual anaplastic sarcomatoid giant cell morphology. Results Microscopically, a small separate PA was found adjacent to the carcinosarcoma. By conventional notion, the PA and carcinosarcoma would be considered related, as carcinosarcomas are well known to arise from PAs (carcinosarcoma ex PA). However, fluorescence in situ hybridization (FISH) assay demonstrated PLAG1 translocation in the carcinosarcoma and HMGA2 translocation in the separate PA. Conclusions These findings support that the carcinosarcoma likely originated from another PA with a PLAG1 translocation or de novo but not from the coexisting PA harboring a different translocation. To our knowledge, the case is the first to demonstrate PLAG1 translocation by FISH in a sarcomatous component of any parotid gland tumor, which may help better classify these tumors. In addition, multiple PAs are commonly found in the salivary gland, and to our knowledge, our case is the first to demonstrate that the same parotid gland can host PAs and PA-related tumors with different translocations.

Accessory parotid gland tumor: a case report

1997 ◽  
Vol 24 (1) ◽  
pp. 105-110 ◽  
Author(s):  
Arata Horii ◽  
Yuichiro Honjo ◽  
Michihiro Nose ◽  
Masayoshi Ozaki ◽  
Jun-Ichi Yoshida
Keyword(s):  
Case Report ◽  
Parotid Gland ◽  
Gland Tumor ◽  
Parotid Gland Tumor ◽  
Accessory Parotid Gland

scholarly journals A case of a parotid gland tumor which was enlarged from the hard and soft palate to the pharyngeal region.

1994 ◽  
Vol 40 (3) ◽  
pp. 470-472
Author(s):  
Kouki TAMAYAMA ◽  
Jun-ichi MURAKAMI ◽  
Hiroto KIMURA ◽  
Toru AKITAYA ◽  
Keiichi IGARASHI ◽  
...  
Keyword(s):  
Parotid Gland ◽  
Soft Palate ◽  
Gland Tumor ◽  
Parotid Gland Tumor ◽  
Pharyngeal Region

Intraductal Papillary Tumors of the Major Salivary Glands

2000 ◽  
Vol 124 (2) ◽  
pp. 291-295 ◽  
Author(s):  
Toshitaka Nagao ◽  
Isamu Sugano ◽  
Osamu Matsuzaki ◽  
Hitoshi Hara ◽  
Yoichiro Kondo ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Salivary Glands ◽  
Salivary Gland Tumor ◽  
Papillary Adenocarcinoma ◽  
Intraductal Papilloma ◽  
Gland Tumor ◽  
Ki 67 ◽  
Parotid Gland Tumor ◽  
Invasive Component ◽  
Papillary Structure

Abstract Intraductal papilloma is an extremely rare benign salivary gland tumor that occurs most commonly in the minor salivary glands. To our knowledge, a malignant counterpart of intraductal papilloma has not been described previously. We report one case each of benign and malignant intraductal papillary tumors. The benign tumor occurred in the sublingual gland and was a typical example of intraductal papilloma, with the exception that we found no previously published reports of this type of tumor in this location. The other patient had a left parotid gland tumor that was architecturally similar to the intraductal papilloma, with the addition of cytologic atypia, intraductal extension, microinvasion, and lymph node metastases. This tumor was diagnosed as intraductal papillary adenocarcinoma with an invasive component. Both patients were alive and well without evidence of recurrence 2 years and 6 months (case 1) and 6 years (case 2) after surgery. Immunohistochemical examination revealed that the tumor cells resembled duct luminal cells in both cases. The 2 tumors had different immunoreactivities for carcinoembryonic antigen, p53, and Ki-67. The malignant counterpart of intraductal papilloma should be considered in the differential diagnosis of salivary gland tumors with a predominantly papillary structure, even though this tumor is extremely rare.

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