Analysis of light signal transduction affecting morphogenesis of perithecia in Neurospora crassa

1997 ◽  
Vol 9 (1) ◽  
pp. 13-22
Author(s):  
Kohji HASUNUMA ◽  
Yasunobu OGURA ◽  
Kazushi ODA ◽  
Naoto YABE
Keyword(s):  
Signal Transduction ◽  
Neurospora Crassa ◽  
Light Signal ◽  
Light Signal Transduction

Light Signal Transduction in Higher Plants

2004 ◽  
Vol 38 (1) ◽  
pp. 87-117 ◽  
Author(s):  
Meng Chen ◽  
Joanne Chory ◽  
Christian Fankhauser
Keyword(s):  
Signal Transduction ◽  
Higher Plants ◽  
Light Signal ◽  
Light Signal Transduction

scholarly journals Photobiology: Light signal transduction and photomorphogenesis

2020 ◽  
Vol 62 (9) ◽  
pp. 1267-1269
Author(s):  
Hongtao Liu ◽  
Rongcheng Lin ◽  
Xing Wang Deng
Keyword(s):  
Signal Transduction ◽  
Light Signal ◽  
Light Signal Transduction

scholarly journals Physical association of the WC-1 photoreceptor and the histone acetyltransferase NGF-1 is required for blue light signal transduction in Neurospora crassa

2012 ◽  
Vol 23 (19) ◽  
pp. 3863-3872 ◽  
Author(s):  
Andrea Brenna ◽  
Benedetto Grimaldi ◽  
Patrizia Filetici ◽  
Paola Ballario
Keyword(s):  
Signal Transduction ◽  
Neurospora Crassa ◽  
Transcriptional Activation ◽  
Light Signal ◽  
Common Mechanism ◽  
Inducible Promoters ◽  
Lxxll Motif ◽  
Light Stimuli ◽  
Environmental Sensor ◽  
H3 Acetylation

In Neurospora crassa and other filamentous fungi, light-dependent–specific phenomena are regulated by transcription factors WC-1 and WC-2. In addition to its transcriptional activity, WC-1 is able to directly sense light stimuli through a LOV sensor domain. Its location in the nucleus and heterodimerization with WC-2, together with the presence of a zinc-finger DNA-binding domain and an environmental sensor domain, all resemble the functional evolutionary architecture adopted by vertebrate nuclear receptors (NRs). Here we describe a scenario in which WC-1 represents a functional orthologue of NRs and acts through association with the chromatin-modifying coactivator NGF-1, which encodes a homologue of the yeast Gcn5p acetyltransferase. To support this view, we show a direct association between WC-1 and NGF-1 that depends on a WC-1 region containing a conserved functional LXXLL motif, a signature previously described as being an exclusive feature of NR/coactivator interaction. Our data suggest that a WC-1/NGF-1 complex is preassembled in the dark on light-inducible promoters and that, after exposure to light stimulation, NGF-1–associated HAT activity leads to histone H3 acetylation and transcriptional activation. Finally, we provide evidence for a NGF-1–independent acetylated form of WC-1. Overall our data indicate that Neurospora and higher eukaryotes share a common mechanism for the signal transduction of environmental stimuli.

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