CORTICOSTEROID THERAPY AND SIDE EFFECTS INVOLVING THE SKIN

1972 ◽  
Vol 2 (22) ◽  
pp. 1220-1220
1977 ◽  
Vol 63 (1) ◽  
pp. 18-25
Author(s):  
M. D. Catterall

AbstractA rationalised approach to topical corticosteroid therapy is presented. Factors which influence the choice of preparation are considered, based upon the concept of ’rank order ’, for both halogenated and non-halogenated steroids. Practical considerations, including choice of base, polythene occlusion and tachyphylaxis are discussed and local and systemic side effects considered in detail.


1993 ◽  
Vol 23 (12) ◽  
pp. 703-708 ◽  
Author(s):  
Victor I Reus ◽  
Owen M Wolkowitz

Dermatology ◽  
2006 ◽  
Vol 212 (4) ◽  
pp. 361-365 ◽  
Author(s):  
Masahiro Kurosawa ◽  
Satoshi Nakagawa ◽  
Masato Mizuashi ◽  
Yoshinori Sasaki ◽  
Maki Kawamura ◽  
...  

Blood ◽  
1962 ◽  
Vol 19 (4) ◽  
pp. 483-500 ◽  
Author(s):  
ROBERT S. SCHWARTZ ◽  
WILLIAM DAMESHEK

Abstract Fourteen patients with autoimmune hemolytic anemia were treated with either 6-mercaptopurine or thioguanine. Nine patients responded and five failed to improve. Eight patients developed side effects, either hematologic or gastrointestinal, of varying degrees of severity; in three the antimetabolite had to be discontinued, while in others adjustment of the dosage or the administration of antacids was sufficient to control side effects. Included in this series are nine patients who failed to respond adequately to corticosteroid therapy; four of these had a good effect from antimetabolite therapy. Although these results indicate that antimetabolites may reverse the course of autoimmune hemolytic anemia, the eventual role of these agents in the treatment of this disorder requires further study.


PEDIATRICS ◽  
1985 ◽  
Vol 75 (2) ◽  
pp. 321-323
Author(s):  
Yehezkel Naveh ◽  
Uri Alon ◽  
Joseph K. Kaftori ◽  
Moshe Berant

Progressive diaphyseal dysplasia is characterized clinically by crippling leg pain, fatigue, headache, poor appetite, muscle weakness, and waddling gait. Twelve affected patients, aged 2 years 4 months to 40 years, were treated with intermittent courses of low doses of prednisone given in a single dose on alternate mornings for periods ranging from 6 months to 10 years. The average initial dose of prednisone was 0.6 mg/kg/d, and average maintenance dose was 0.3 mg/kg/d. Relief of all crippling symptoms was achieved in all patients. No untoward serious side effects have been observed, and the growth of children was not slowed. However, corticosteroid therapy should be restricted to patients suffering from crippling pain. The mechanism through which steroids act remains undefined.


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