Pulmonary disease in a child caused by atypical mycobacteria

1984 ◽  
Vol 141 (4) ◽  
pp. 242-243 ◽  
Author(s):  
Anthony J. Proust ◽  
Helen Wiles
PEDIATRICS ◽  
1960 ◽  
Vol 26 (4) ◽  
pp. 563-565
Author(s):  
Saul Blatman ◽  
Gardner Middlebrook

The importance of the "Unclassified Mycobacteria" as agents of human disease is becoming increasingly evident.1 Those who have previously considered many strains of Mycobacteria to be nonpathogenic are now investigating their role in cervical adenitis, in pulmonary disease resembling tuberculosis, and as the etiologic agents in certain types of skin granulomata. In pediatrics the problem of cervical adenitis has been a particularly difficult one, and perhaps some of the perplexities of "tuberculous adenitis" can now be solved.2-4 Some investigators chose to label this group of acid-fast organisms as the "Atypical Mycobacteria"; Middlebrook and his coworkers use the term "Unclassified Mycobacteria," because as Mycobacteria they are not atypical; they are simply as yet poorly studied and unclassified.


Tubercle ◽  
1957 ◽  
Vol 38 (6) ◽  
pp. 387-396 ◽  
Author(s):  
E. Nassau ◽  
G.M. Hamilton

2020 ◽  
Vol 14 (1) ◽  
Author(s):  
Elsayed Ahmed Fahmy ◽  
Heba Wagih Abdelwahab ◽  
Heba Elsayed Eldegla ◽  
Mohammed Khairy Fahmy Elbadrawy

Abstract Background Exacerbations of chronic obstructive pulmonary disease (COPD) represent important events in the management of COPD because of its negative impact on health status and disease progression. The etiology of acute exacerbations of chronic obstructive pulmonary disease (COPDAE) is heterogeneous and still under discussion. So, this study was planned to investigate the role of infectious pathogens (fungi and atypical mycobacteria in addition to the well-known bacteria) in patients with COPD exacerbation in our locality. Results This observational cross-sectional study was conducted on 100 patients with acute exacerbation of COPD. Sputum specimens were collected for mycobacterial and fungal examination in addition to routine sputum bacteriology. All sputum samples were negative for typical and atypical mycobacteria whereas sputum samples of 18 patients (18%) were negative for fungi. Mixed fungal growth was found in 19 patients (19%). Candida was isolated from 67 patients (67%), Aspergillus was isolated from 27 patients (27%), Alternaria was isolated from 3 patients (3%), and other fungi were isolated from 4 patients (4%). As regards sputum bacteriology, sputum samples of 49 patients (49%) have bacterial growth. Streptococcus pneumoniae was isolated from 16 samples (16%) and represents the most frequent bacterial isolate in this study. Conclusion The present study indicates that typical and atypical mycobacteria have no role in COPD exacerbations in our locality. However, fungi and bacteria may have a role in COPD exacerbations.


Pathology ◽  
1979 ◽  
Vol 11 (2) ◽  
pp. 283-287 ◽  
Author(s):  
Z.M. Blacklock ◽  
D.J. Dawson

1987 ◽  
Vol 80 (12) ◽  
pp. 1488-1497 ◽  
Author(s):  
JOHN H. WOODRING ◽  
H MAC VANDIVIERE ◽  
IRENE G. MELVIN ◽  
MARCUS L. DILLON

2020 ◽  
Vol 29 (2) ◽  
pp. 864-872
Author(s):  
Fernanda Borowsky da Rosa ◽  
Adriane Schmidt Pasqualoto ◽  
Catriona M. Steele ◽  
Renata Mancopes

Introduction The oral cavity and pharynx have a rich sensory system composed of specialized receptors. The integrity of oropharyngeal sensation is thought to be fundamental for safe and efficient swallowing. Chronic obstructive pulmonary disease (COPD) patients are at risk for oropharyngeal sensory impairment due to frequent use of inhaled medications and comorbidities including gastroesophageal reflux disease. Objective This study aimed to describe and compare oral and oropharyngeal sensory function measured using noninstrumental clinical methods in adults with COPD and healthy controls. Method Participants included 27 adults (18 men, nine women) with a diagnosis of COPD and a mean age of 66.56 years ( SD = 8.68). The control group comprised 11 healthy adults (five men, six women) with a mean age of 60.09 years ( SD = 11.57). Spirometry measures confirmed reduced functional expiratory volumes (% predicted) in the COPD patients compared to the control participants. All participants completed a case history interview and underwent clinical evaluation of oral and oropharyngeal sensation by a speech-language pathologist. The sensory evaluation explored the detection of tactile and temperature stimuli delivered by cotton swab to six locations in the oral cavity and two in the oropharynx as well as identification of the taste of stimuli administered in 5-ml boluses to the mouth. Analyses explored the frequencies of accurate responses regarding stimulus location, temperature and taste between groups, and between age groups (“≤ 65 years” and “> 65 years”) within the COPD cohort. Results We found significantly higher frequencies of reported use of inhaled medications ( p < .001) and xerostomia ( p = .003) in the COPD cohort. Oral cavity thermal sensation ( p = .009) was reduced in the COPD participants, and a significant age-related decline in gustatory sensation was found in the COPD group ( p = .018). Conclusion This study found that most of the measures of oral and oropharyngeal sensation remained intact in the COPD group. Oral thermal sensation was impaired in individuals with COPD, and reduced gustatory sensation was observed in the older COPD participants. Possible links between these results and the use of inhaled medication by individuals with COPD are discussed.


Sign in / Sign up

Export Citation Format

Share Document