scholarly journals Lymphocytic Esophagitis

2017 ◽  
Author(s):  
Dane Christina Daoud ◽  
Mickael Bouin
Keyword(s):  
Lymphocytic Esophagitis

scholarly journals A141 SPONTANEOUS ESOPHAGEAL PERFORATION: AN UNREPORTED COMPLICATION OF LYMPHOCYTIC ESOPHAGITIS

2021 ◽  
Vol 4 (Supplement_1) ◽  
pp. 128-129
Author(s):  
A LAGROTTERIA ◽  
A W Collins ◽  
A Someili ◽  
N Narula
Keyword(s):  
Computed Tomography ◽  
Emergency Department ◽  
Case Report ◽  
Proton Pump Inhibitor ◽  
Proton Pump ◽  
Esophageal Perforation ◽  
Distal Esophagus ◽  
Chest Discomfort ◽  
History Of ◽  
Lymphocytic Esophagitis

Abstract Background Lymphocytic esophagitis is a new and rare clinicopathological entity. It is a histological pattern characterized by lymphocytic infiltrate without granulocytes. Its etiology and clinical significance remains unclear. The clinical manifestations are typically mild, with reflux and dysphagia the most commonly reported symptoms. Aims We describe a case report of spontaneous esophageal perforation associated with lymphocytic esophagitis. Methods Case report Results A previously well 31-year-old male presented to the emergency department with acute food impaction. His antecedent symptoms were acute chest discomfort and continuous odynophagia following his most recent meal, with persistent globus sensation. The patient had no reported history of allergies, atopy, rhinitis, or asthma. A previous history of non-progressive dysphagia was noted after resuscitation. Emergent endoscopy revealed no food bolus, but a deep 6 cm mucosal tear in the upper-mid esophagus extending 24 to 30 cm from the incisors. Chest computed tomography observed small volume pneumoperitoneum consistent with esophageal perforation. The patient’s recovery was uneventful; he was managed conservatively with broad-spectrum antibiotics, proton pump inhibitor therapy, and a soft-textured diet. Endoscopy was repeated 48 hours later and revealed considerable healing with only a residual 3-4cm linear laceration. Histology of biopsies taken from the mid and distal esophagus demonstrated marked infiltration of intraepithelial lymphocytes. There were no eosinophils or neutrophils identified, consistent with a diagnosis of lymphocytic esophagitis. Autoimmune indices including anti-nuclear antibodies and immunoglobulins were normal, ruling out a contributory autoimmune or connective tissue process. The patient was maintained on a proton pump inhibitor (pantoprazole 40 mg once daily) following discharge. Nearly six months following his presentation, the patient had a recurrence of symptoms prompting representation to the emergency department. He described acute onset chest discomfort while eating turkey. Computed tomography of the chest redemonstrated circumferential intramural gas in the distal esophagus and proximal stomach. Conclusions Esophageal perforation is a potentially life-threatening manifestation of what had been considered and described as a relatively benign condition. From isolated dysphagia to transmural perforation, this case significantly expands our current understanding of the clinical spectrum of lymphocytic esophagitis. Funding Agencies None

Lymphocytic Esophagitis With CD4 T-cell–predominant Intraepithelial Lymphocytes and Primary Esophageal Motility Abnormalities

2015 ◽  
Vol 39 (11) ◽  
pp. 1558-1567 ◽  
Author(s):  
Yue Xue ◽  
Arief Suriawinata ◽  
Xiaoying Liu ◽  
Zhongze Li ◽  
Scott Gabbard ◽  
...  
Keyword(s):  
T Cell ◽  
Esophageal Motility ◽  
Intraepithelial Lymphocytes ◽  
Cd4 T Cell ◽  
Lymphocytic Esophagitis

Lymphocytic Esophagitis: A Case Series Profiling Disease Characteristics

2017 ◽  
Vol 152 (5) ◽  
pp. S892 ◽  
Author(s):  
Ahmed Al-Mazroui ◽  
Michael A. Scaffidi ◽  
Thurarshen Jeyalingam ◽  
Daniel J. Low ◽  
Rishad Khan ◽  
...  
Keyword(s):  
Case Series ◽  
Disease Characteristics ◽  
Lymphocytic Esophagitis

Mo1209 TREATMENT OF LYMPHOCYTIC ESOPHAGITIS IN A LARGE TERTIARY ACADEMIC INSTITUTION

2020 ◽  
Vol 158 (6) ◽  
pp. S-827-S-828
Author(s):  
Malcolm Irani ◽  
Shaadi Abughazaleh ◽  
Michelle Jones-Pauley ◽  
Daniel Duhon ◽  
Vineet Gudsoorkar ◽  
...  
Keyword(s):  
Academic Institution ◽  
Lymphocytic Esophagitis

scholarly journals A229 CLINICAL AND ENDOSCOPIC CHARACTERISTICS OF LYMPHOCYTIC ESOPHAGITIS

2018 ◽  
Vol 1 (suppl_1) ◽  
pp. 401-401
Author(s):  
T JEYALINGAM ◽  
A Almazroui ◽  
C Streutker ◽  
M A Scaffidi ◽  
D J Low ◽  
...  
Keyword(s):  
Endoscopic Characteristics ◽  
Lymphocytic Esophagitis

scholarly journals Lymphocytic Esophagitis in Nonachalasia Primary Esophageal Motility Disorders

2016 ◽  
Vol 40 (12) ◽  
pp. 1679-1685 ◽  
Author(s):  
Juan Putra ◽  
Kristen E. Muller ◽  
Zilla H. Hussain ◽  
Siddhartha Parker ◽  
Scott Gabbard ◽  
...  
Keyword(s):  
Esophageal Motility ◽  
Esophageal Motility Disorders ◽  
Motility Disorders ◽  
Primary Esophageal Motility Disorders ◽  
Lymphocytic Esophagitis

Esophageal Pityriasis Lichenoides Chronica

2020 ◽  
Vol 154 (Supplement_1) ◽  
pp. S70-S71
Author(s):  
S Dasaraju ◽  
S Liu ◽  
O Elkadi
Keyword(s):  
Pemphigus Vulgaris ◽  
Clinical History ◽  
Skin Condition ◽  
Esophageal Mucosa ◽  
Cell Hyperplasia ◽  
Pityriasis Lichenoides ◽  
Gradual Development ◽  
History Of ◽  
Acute Form ◽  
Lymphocytic Esophagitis

Abstract Casestudy: Pityriasis Lichenoides is an uncommon inflammatory skin condition of unknown cause that ranges from mild chronic form to a more severe acute eruption. The mild form, pityriasis lichenoid chronica (PLC), is characterized by the gradual development of symptomless, small scaling papules that spontaneously flatten and regress over weeks. The acute form is characterized by the sudden eruption of small scaling papules that develops into blisters and crusted red brown spots. This acute form is called pityriasis lichenoides et varioliformis acuta (PLEVA). Both forms usually involve the skin of the trunk and proximal extremities. Visceral involvement is not a well described phenomenon. We report a case of a 69-year-old female with significant history of PLC controlled by immunosuppressive therapy. The patient presented with odynophagia and dysphagia that occurred after a period of discontinuation of her PLC treatment. She underwent endoscopy which showed distal esophageal narrowing and stricture. Biopsy revealed squamous esophageal mucosa with marked intraepithelial lymphocytosis along with basal cell hyperplasia, acanthosis, vacuolation and prominent apoptosis in the epithelial cells. PAS, CMV and HSV stains showed no fungal or viral organisms. The esophagus is commonly involved in a number of dermatologic conditions including pemphigus vulgaris, erythema multiforme, epidermolysis bullosa, lichen planus and lichen sclerosis. The pattern of involvement is often in the form of “lymphocytic esophagitis”. To our knowledge, there are no reported cases in the literature on PLC involving the esophagus. While the diagnosis heavily relies on clinical history of PLC, awareness of potential involvement of the esophagus and attention to certain endoscopic and morphological details may better help classify esophagitis biopsies.

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