The dental status of 148 patients aged 18 to 22 years. All students who were diagnosed with generalized catarrhal gingivitis (46) were carried out removal of dental plaque with ozonation of the environment. The results of clinical studies indicate the high efficiency of the use of the removal of dental plaque using low-frequency ultrasound using an ozonized contact medium in the treatment of chronic generalized catarrhal gingivitis. The treatment carried out using this method contributed to the elimination of inflammation, the normalization of blood circulation in the gums. 3 months after the treatment, the achieved effect was preserved, which was confirmed by the data of clinical and functional research methods. Despite a slight increase in inflammation in the gums and a deterioration in microcirculation indicators, even a year after treatment, the indicators characterizing the degree of inflammatory and microcirculatory disorders in the gums retained significant differences compared to the values obtained before the treatment.