scholarly journals Imaging Features and Floating-Ice Sign of Primary Lymphoma of the Bone

2020 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Bao-Hai Yu ◽  
Tao Sun ◽  
Lei Cao ◽  
Shu-Man Han ◽  
Wen-Juan Wu ◽  
...  

Background: The imaging presentation of primary bone lymphoma is unclear. Objectives: The present study aimed to investigate the imaging presentations of primary bone lymphoma especially a specific “floating-ice” sign. Patients and Methods: Forty one patients with primary bone lymphoma confirmed by pathology with 27 males and 14 females and an age range of 2 - 76 (mean = 40) years were enrolled. The clinical and imaging data were analyzed. Results: The tumor involved long bones in 17 cases, flat bones in 12, spine in eight and irregular bones in four cases. The imaging presentations were divided into five types: infiltrative type in nine cases (22%), osteolytic in 14 cases (34.1%), osteosclerotic in four cases (9.8%), mixed in 11 cases (26.8%) including four cases with a “floating-ice” sign and cystic in three cases (7.3%). In plain radiography, only three of four long bone lesions in children had a varying degree of periosteal reaction. Among 20 cases with CT scanning, sixteen had soft tissue masses, seventeen had ill-defined margins, and three had well-defined margins with sclerotic rims. Among twelve patients with MRI, ten had soft tissue masses with well-defined margins. MRI demonstrated a greater extent of lesion than CT. In MRI T1 weighted image (T1 WI), isointense signal was seen in three cases, hypointense signal in five and mixed signal in four. In T2 WI, isointense and hypointense signal was detected in five cases, hyperintense signal in three and mixed hyperintense signal in four. Conclusion: Primary bone lymphoma occurs most frequently in long and flat bones as infiltrative osteolytic destruction, and combined plain radiographs, CT and MRI help obtain a correct diagnosis.

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Lei Cao ◽  
Jin-Xu Wen ◽  
Shu-Man Han ◽  
Hui-Zhao Wu ◽  
Zhi-Gang Peng ◽  
...  

Abstract Background To investigate the imaging features of hemangiomas in long tabular bones for better diagnosis. Methods Twenty-four patients with long bone hemangiomas confirmed by pathology were enrolled. Nineteen patients had plain radiography, fourteen patients had computed tomography (CT) and eleven had magnetic resonance imaging (MRI). The hemangioma was divided into medullary [13], periosteal [6] and intracortical type [5]. Results Among 19 patients with plain radiography, eleven patients were medullary, three periosteal, and five intracortical. In the medullary type, the lesion was primarily osteolytic, including five cases with irregular and unclear rims and one lesion having osteosclerotic and unclear rims. In three patients with the periosteal type, the lesion had clear rims with involvement of the cortical bone in the form of bone defect, including two cases with local thickened bone periosteum and one case having expansile periosteum. Five intracortical hemangiomas had intracortical osteolytic lesions with clear margins. Among 14 patients with CT imaging, 8 cases were medullary, three periosteal, and three intracortical. Among 8 medullary hemangiomas, one had ground glass opacity, and seven had osteolytic, expansile lesions like soft tissue density with no calcification. In three periosteal cases, the lesion was osteolytic with thickened periosteum and narrowed medullary cavity. In three intracortical hemangiomas, the lesion was of even soft tissue density with no calcification. Among 11 patients with MRI imaging, seven were medullary, two periosteal, and two intracortical. Among 7 medullary lesions, six were of hypointense signal on T1WI and hyperintensesignal on T2 WI. In two periosteal cases, the periosteum was thickened, with one case being of equal signal, and the other having no signal. Two intracortical hemangiomas were both of slightly low signal on T1WI but hyperintense signal on T2WI. Conclusions The long bone hemangiomas had characteristic cystic honeycomb-like presentations in plain radiograph. CT and MRI imagings are helpful for diagnosis of hemangiomas in long bone.


2020 ◽  
pp. 100-107
Author(s):  
Michele Boffano ◽  
Nicola Ratto ◽  
Martina Rezzoagli ◽  
Andrea Conti ◽  
Pietro Pellegrino ◽  
...  

Primary non-Hodgkin bone lymphoma (PBL) is a rare disease that accounts for <2% of all lymphomas in adults. PBL can be monostotic or polyostotic, mainly causing destructive and lytic bone lesions frequently located in the femur, humerus, and pelvis. PBL is rarely considered a differential diagnosis of the osteolytic tumor. In addition, PBL is not uncommonly diagnosed with delay because patients do not experience symptoms nor show objective abnormalities in the early stage of disease. Here, we reported a 60-year-old woman with a PBL of the elbow.


2019 ◽  
Vol 2019 ◽  
pp. 1-5
Author(s):  
Grace Kennedy ◽  
Phil Weir ◽  
Kevin Johnston ◽  
Patrick Elder

Introduction. Primary bone lymphoma (PBL) is a rare bone malignancy which may present with atraumatic pain, swelling, or pathological fracture. Whilst the femur is the most commonly affected site, any bone may be involved. PBL should be distinguished from other bone lesions to determine clinical management. Case Report. We report the case of an 89-year-old gentleman who presented to the local emergency department with atraumatic hip pain and inability to weight-bear. Multimodal imaging showed evidence of a tumor involving the proximal femur and adjacent acetabulum with an associated pathological intertrochanteric fracture. Biopsy specimens demonstrated this to be PBL of the diffuse large B-cell subtype. No other disease foci or nodal involvement was identified. The patient underwent proximal femoral replacement and acetabular reconstruction prior to commencing R-Mini-CHOP chemotherapy, during which time he has been permitted to fully weight-bear. Conclusion. To our knowledge, this is the first reported case of a patient having PBL with both femoral and acetabular involvements. Due to its infrequent occurrence, evidence remains limited to advise therapeutic guidelines. Our practice concurs with literature suggesting that surgery be reserved for cases of pathological fracture. However, the merits of undergoing surgical fixation prior to chemoradiation treatment have been considered.


Author(s):  
abbas mofidi ◽  
Mohsen Esfandbod ◽  
Ehsan Pendar ◽  
Masoud Mortezazadeh ◽  
Alireza hadizadeh

In this article, we report a 34-year-old man who presented with progressive hip pain and osteolytic bone lesions . Primary workup included Core needle biopsies manifested as osteomyelitis; however as no sign of remission was observed, an open biopsy considered which revealed primary bone lymphoma.


2012 ◽  
Vol 47 (3) ◽  
pp. 213 ◽  
Author(s):  
So Yeon Kim ◽  
Dong-Yeop Shin ◽  
Seung-Sook Lee ◽  
Cheolwon Suh ◽  
Jae-Yong Kwak ◽  
...  

2014 ◽  
Vol 65 (1) ◽  
pp. 52-59 ◽  
Author(s):  
Tony Sedlic ◽  
Elena P. Scali ◽  
Wai-Kit Lee ◽  
Sadhna Verma ◽  
Silvia D. Chang

Inflammatory pseudotumours are uncommonly encountered lesions in the abdomen and pelvis that often present with variable and nonspecific imaging features. They may mimic other more common lesions, including malignancy. Within the appropriate clinical context, inflammatory pseudotumours merit consideration in the differential diagnosis of soft-tissue masses within the abdomen and pelvis. A preoperative diagnosis of inflammatory pseudotumour, established through biopsy, may help to differentiate this benign entity from malignancy. In this article, we reviewed the imaging features of inflammatory pseudotumours of the abdomen and pelvis, including liver, spleen, bowel, retroperitoneum, kidney, bladder, uterus, and adnexa.


2009 ◽  
Vol 51 (1) ◽  
pp. 39-49 ◽  
Author(s):  
Alvaro Alencar ◽  
David Pitcher ◽  
Gerald Byrne ◽  
Izidore S. Lossos

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