Sepsis Caused by Elizabethkingia meningoseptica Successfully Treated by Polymyxin B: A Case Report

2020 ◽  
Vol 22 (2) ◽  
Author(s):  
Meiling Yu ◽  
Benquan Qi ◽  
Qi Zou ◽  
Shengyong Zheng ◽  
Chen Liu ◽  
...  
2018 ◽  
Vol 4 (3) ◽  
pp. 96-100
Author(s):  
Manuela Arbune ◽  
Silvia Fotea ◽  
Aurel Nechita ◽  
Victorita Stefanescu

Abstract Background: Elizabethkingia meningoseptica are Gram-negative rod bacteria which are commonly found in the environment. The bacteria have also been associated with nosocomial infections, having been isolated on contaminated medical equipment, especially in neonatal wards. Case report: Here, we present the case of a premature female infant born at 33 weeks’ gestational age, with neonatal meningitis. The onset was marked by fever, in the 5th day of life, while in the Neonatal Intensive Care Unit. The patient was commenced on Gentamicin and Ampicillin, but her clinical condition worsened. Psychomotor agitation and food refusal developed in the 10th day of life, and a diagnosis of bacterial meningitis was made based on clinical and cerebrospinal fluid findings. A strain of Elizabethkingia meningoseptica sensitive to Vancomycin, Rifampicin and Clarithromycin was isolated from cerebrospinal fluid. First-line antibiotic therapy with Meropenem and Vancomycin was adjusted by replacing Meronem with Piperacillin/Tazobactam and Rifampicin. The patient’s clinical condition improved, although some isolated febrile episodes were still present. The cerebrospinal fluid was normalized after 6 weeks of antibiotic treatment, although periventriculitis and tetraventricular hydrocephalus were revealed by imaging studies. Neurosurgical drainage was necessary. Conclusion: Elizabethkingia meningoseptica can cause severe infection, with high risk of mortality and neurological sequelae in neonates. Intensive care and multidisciplinary interventions are crucial for case management.


2021 ◽  
Vol 10 ◽  
pp. 1
Author(s):  
Monastra Luca ◽  
Perrella Alessandro ◽  
Garzia Raffaele ◽  
Fraganza Fiorentino

Author(s):  
Manisha Kharbanda ◽  
Parag Bagad ◽  
Sunanda Dey

Abstract Elizabethkingia meningoseptica is a Gram-negative bacillus. It is known for causing neonatal meningitis and pneumonia, sepsis in case of immunocompromised patients. It can be found in hospital and natural environments. It may exist in freshwater, salt water, and soil. It was previously known as Flavobacterium and Chryseobacterium meningosepticum.Contact lens-induced keratitis with E. meningoseptica which we are reporting is the second case report till date. It has striking resemblance with the case that was published earlier, with minimal difference in presentation, but significant difference in the antimicrobial sensitivity. Most importantly, we also found this infection in healthy individual with no underlying disease.Thus, we strongly support the case report that was published earlier, and though rare, this microbe should be considered as potential pathogen for contact lens-related keratitis, and increasing resistance to the antimicrobial agents should also be kept in mind.


Author(s):  
Xuben Yu ◽  
Jingye Pan ◽  
Ziye Zhou ◽  
Xin Wen ◽  
Ying Dai ◽  
...  

2011 ◽  
Vol 5 (1) ◽  
Author(s):  
Paul P Connell ◽  
Sanj Wickremasinghe ◽  
Uma Devi ◽  
Mary Jo Waters ◽  
Penelope J Allen

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