scholarly journals A Case of Pigmented Bowen Disease on the Finger Mimicking Melanoma Showing a Chaos Pattern on Dermoscopy

2020 ◽  
pp. e2020079
Author(s):  
Ryoji Kurita ◽  
Yaei Togawa ◽  
Keisuke Suehiro ◽  
Hiroyuki Matsue
Keyword(s):  

1973 ◽  
Vol 108 (3) ◽  
pp. 367-370 ◽  
Author(s):  
S. L. Andersen


2010 ◽  
Vol 62 (2) ◽  
pp. 356-357 ◽  
Author(s):  
Stefano Cavicchini ◽  
Athanasia Tourlaki ◽  
Massimo Ghislanzoni ◽  
Paola Alberizzi ◽  
Elvio Alessi
Keyword(s):  


2000 ◽  
Vol 124 (3) ◽  
pp. 427-430 ◽  
Author(s):  
John D. Williamson ◽  
Maria I. Colome ◽  
Aysegul Sahin ◽  
Alberto G. Ayala ◽  
L. Jeffrey Medeiros

Abstract Bowen disease is a variant of squamous cell carcinoma in situ. In some cases a pagetoid growth pattern can be observed with cytologically atypical clear cells arranged singly and in nests. The differential diagnosis of pagetoid Bowen disease includes primarily Paget disease and malignant melanoma in situ, as well as other less common entities. Two cases of pagetoid Bowen disease are described, one in a 65-year-old man with a thigh lesion and the other in a 25-year-old man with a lesion in the penile/scrotal region. Neither patient had clinical evidence of an internal malignant neoplasm. In both cases, the neoplastic cells were positive for cytokeratin (CK) 7 and CK 19 and were negative for CK 18, CK 20, carcinoembryonic antigen, GCDFP-15, c-erbB2, S100, and HMB-45. In aggregate, these findings support the diagnosis of pagetoid Bowen disease. Previously, others have shown that CK 7 is an almost invariable marker of Paget disease. Thus, we report these two cases to illustrate that CK 7 can be expressed by pagetoid Bowen disease and should not be a cause of confusion in the differential diagnosis.



2018 ◽  
Vol 22 ◽  
pp. 14-16 ◽  
Author(s):  
M. Fernández-Guarino ◽  
M.L. González Morales ◽  
Israel Bernal ◽  
A.I. Sánchez Adrada ◽  
Sandra Pierri Ugia ◽  
...  


2020 ◽  
Vol 33 (4) ◽  
Author(s):  
Alessia Provini ◽  
Salvatore Ruggeri ◽  
Cinzia Mazzanti ◽  
Maria Antonietta Pilla ◽  
Francesca Ricci ◽  
...  


2017 ◽  
Vol 5 (4) ◽  
pp. 545-546 ◽  
Author(s):  
Georgi Tchernev ◽  
Torello Lotti ◽  
Uwe Wollina ◽  
Serena Gianfaldoni ◽  
Ilia Lozev ◽  
...  

A 60-year-old male patient presented with complaints of persistent red to a brown-colored plaque on his scrotum, with duration of approximately three years. The patient had been treated with oral and topical antifungals for inguinal tinea for several months and after that with topical corticosteroids for eczema for several more months. None of the regimens achieved any therapeutic effect. The histopathological evaluation revealed the presence of atypical keratinocytes in all layers of the epidermis with the altered epidermal pattern, spread parabasal mitotic activity, without secondary satellites, multiple dyskeratotic cells and multinucleated cells. The diagnosis of an intraepithelial non-invasive squamous cell carcinoma, associated with koilocytic dysplasia and hyperplasia was made, meeting the criteria for Bowen disease. An elliptic surgical excision of the lesion was made, while the defect was closed with single stitches, with excellent therapeutic and aesthetic result. First described by John T. Bowen in 1912, Bowen disease (BD) represents a squamous cell carcinoma (SCC) in situ with the potential for significant lateral spread. Treatment options include the application of topical 5-flurorouracil cream – useful in non-hairy areas, imiquimod cream or destructive methods such as radiation, curettage, cryotherapy, laser ablation and photodynamic therapy, especially useful in nail bed involvement. Despite the early lesions, surgical excision is the preferred treatment option, regarding the potential malignant transformation risk.



2013 ◽  
Vol 19 (6) ◽  
Author(s):  
Erin M Wilmer ◽  
Kachiu C Lee ◽  
H William Higgins II ◽  
Antonio P Cruz
Keyword(s):  


2004 ◽  
Vol 43 (6) ◽  
pp. 419-422 ◽  
Author(s):  
George T. Liu ◽  
Michael O. Lovell ◽  
John S. Steinberg


2018 ◽  
Vol 40 (11) ◽  
pp. 841-845 ◽  
Author(s):  
Takeshi Namiki ◽  
Keiko Miura ◽  
Hiroo Yokozeki ◽  
Shin-ichi Ansai
Keyword(s):  


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