Primary Pulmonary Pleomorphic Adenoma

Abstract Primary pleomorphic adenoma of the lung is an uncommon condition. We present a case of primary pulmonary pleomorphic adenoma and its immunohistologic features. The presence of immunoreactivity to both anticytokeratin and antivimentin antibodies for its epithelial components is suggestive of a primary pulmonary lesion. Its high proliferation index and its immunoreactivity to tumor regulatory gene p16(INK4A) are features that, to our knowledge, have not been reported previously. They may have a role in the frequent recurrence of these tumors many years after their apparently complete excision. Detailed genetic investigation and long-term follow-up of this rare tumor will aid in the characterization of its biologic profile.

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Post-Operative Dysphagia in Anterior Cervical Discectomy and Fusion

Annals of Otology Rhinology & Laryngology ◽

10.1177/00034894211015582 ◽

2021 ◽

pp. 000348942110155

Author(s):

Leonard Haller ◽

Khush Mehul Kharidia ◽

Caitlin Bertelsen ◽

Jeffrey Wang ◽

Karla O’Dell

Keyword(s):

Risk Factors ◽

Medical Records ◽

Assessment Tool ◽

Demographic Data ◽

Anterior Cervical Discectomy ◽

Cervical Discectomy ◽

Long Term Follow Up

Objective: We sought to identify risk factors associated with long-term dysphagia, characterize changes in dysphagia over time, and evaluate the incidence of otolaryngology referrals for patients with long-term dysphagia following anterior cervical discectomy with fusion (ACDF). Methods: About 56 patients who underwent ACDF between May 2017 to February 2019 were included in the study. All patients were assessed for dysphagia using the Eating Assessment Tool (EAT-10) survey preoperatively and late postoperatively (≥1 year). Additionally, 28 patients were assessed for dysphagia early postoperatively (2 weeks—3 months). Demographic data, medical comorbidities, intraoperative details, and post-operative otolaryngology referral rates were collected from electronic medical records. Results: Of the 56 patients enrolled, 21 patients (38%) had EAT-10 scores of 3 or more at long-term follow-up. None of the demographics, comorbidities, or surgical factors assessed were associated with long-term dysphagia. Patients who reported no long-term dysphagia had a mean EAT-10 score of 6.9 early postoperatively, while patients with long-term symptoms had a mean score of 18.1 ( P = .006). Of the 21 patients who reported persistent dysphagia symptoms, 3 (14%) received dysphagia testing or otolaryngology referrals post-operatively. Conclusion: Dysphagia is a notable side effect of ACDF surgery, but there are no significant demographics, comorbidities, or surgical risk factors that predict long-term dysphagia. Early postoperative characterization of dysphagia using the EAT-10 questionnaire can help predict long-term symptoms. There is inadequate screening and otolaryngology follow-up for patients with post-ACDF dysphagia.

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Carcinoid of the Extra-Hepatic Bile Duct: A Case Report with Long-Term Follow-up and Review of Literature

The American Surgeon ◽

10.1177/000313480807400121 ◽

2008 ◽

Vol 74 (1) ◽

pp. 87-90 ◽

Cited By ~ 3

Author(s):

Niraj J. Gusani ◽

J. Wallis Marsh ◽

Michael A. Nalesnik ◽

Mitchell E. Tublin ◽

T. Clark Gamblin

Keyword(s):

Bile Duct ◽

Carcinoid Tumor ◽

Extrahepatic Bile Duct ◽

Strong Support ◽

Complete Excision ◽

Term Survival ◽

Long Term Survival ◽

Long Term Follow Up

Extrahepatic bile duct tumors, 80 per cent of which are adenocarcinomas, are rare neoplasms accounting for less than two per cent of all cancers. Carcinoid tumor of the extrahepatic bile ducts is a reportable lesion, with only approximately 50 cases described in the literature since 1959. We present a case of a primary extrahepatic bile duct carcinoid tumor resected for cure with the longest reported follow-up time (11 years) after surgery. We also summarize the existing literature with regard to this rare tumor. Our case lends strong support to the notion that extrahepatic biliary carcinoids are generally indolent lesions that, if aggressively resected, can result in excellent long-term survival. Complete excision with clear margins seems to provide the best chance of obtaining long-term survival and cure.

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Postoperative complications after removal of pleomorphic adenoma from the parotid gland: A long-term follow up of 297 patients from 2002 to 2016 and a review of publications

British Journal of Oral and Maxillofacial Surgery ◽

10.1016/j.bjoms.2019.08.008 ◽

2019 ◽

Vol 57 (10) ◽

pp. 998-1002 ◽

Cited By ~ 3

Author(s):

Paola Bonavolontà ◽

Giovanni Dell'Aversana Orabona ◽

Fabio Maglitto ◽

Vincenzo Abbate ◽

Umberto Committeri ◽

...

Keyword(s):

Postoperative Complications ◽

Parotid Gland ◽

Pleomorphic Adenoma ◽

Long Term Follow Up

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Proliferation Index of Nonfunctioning Pituitary Adenomas: Correlations with Clinical Characteristics and Long-term Follow-up Results

Neurosurgery ◽

10.1093/neurosurgery/47.6.1313 ◽

2000 ◽

Vol 47 (6) ◽

pp. 1313-1319 ◽

Cited By ~ 5

Author(s):

Marco Losa ◽

Alberto Franzin ◽

Francesca Mangili ◽

Maria Rosa Terreni ◽

Raffaella Barzaghi ◽

...

Keyword(s):

Pituitary Adenomas ◽

Clinical Characteristics ◽

Proliferation Index ◽

Nonfunctioning Pituitary Adenomas ◽

Long Term Follow Up

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Long-term follow up of feline leukemia virus infection and characterization of viral RNA loads using molecular methods in tissues of cats with different infection outcomes

Virus Research ◽

10.1016/j.virusres.2014.12.025 ◽

2015 ◽

Vol 197 ◽

pp. 137-150 ◽

Cited By ~ 24

Author(s):

A. Katrin Helfer-Hungerbuehler ◽

Stefan Widmer ◽

Yvonne Kessler ◽

Barbara Riond ◽

Felicitas S. Boretti ◽

...

Keyword(s):

Virus Infection ◽

Leukemia Virus ◽

Molecular Methods ◽

Viral Rna ◽

Feline Leukemia Virus ◽

Long Term Follow Up

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In vitro characterization of commercial factor VIII concentrates: Long-term follow-up

Blut Zeitschrift für die gesamte Blutforschung ◽

10.1007/bf00320384 ◽

1984 ◽

Vol 49 (1) ◽

pp. 53-59 ◽

Cited By ~ 1

Author(s):

C. Miyashita ◽

P. Hellstern ◽

M. K�hler ◽

G. Blohn ◽

E. Wenzel

Keyword(s):

Factor Viii ◽

In Vitro Characterization ◽

Long Term Follow Up ◽

Factor Viii Concentrates

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Long-term Use of Le Fort I Osteotomy for the Management of Nasopharyngeal Rhinosporidiosis: A Case Series

Ear Nose & Throat Journal ◽

10.1177/0145561318097010-1103 ◽

2018 ◽

Vol 97 (10-11) ◽

pp. E36-E43

Author(s):

Vikram Shetty ◽

Akshaya Kulkarni ◽

Suman Banerjee

Keyword(s):

Nasal Mucosa ◽

Treatment Protocol ◽

Case Series ◽

Le Fort I Osteotomy ◽

Complete Excision ◽

Le Fort ◽

Long Term Follow Up ◽

Le Fort I

Rhinosporidiosis is a rare, chronic, granulomatous infection of the mucous membranes that mainly involves the nose and nasopharynx; it occasionally involves the pharynx, conjunctiva, larynx, trachea and, rarely, the skin. The characteristic clinical features of this disease include the formation of painless polyps in the nasal mucosa or the nasopharynx that bleed easily on touch. At our center, excision of the lesion with a Le Fort I osteotomy is carried out in patients (1) in whom two or more previous attempts at excision of biopsy-proven rhinosporidiosis arising from the nasal mucosa was carried out or (2) in whom the rhinosporidiosis arises from the nasophayrngeal mucosa and/or extranasal sites. In this article we retrospectively present 7 cases in which, according to our inclusion criteria, complete excision of the lesion was carried out with a Le Fort I osteotomy. Excellent visualization of the entire maxillary and ethmoidal air cells after the down-fracture of the maxilla helped in the total removal of the lesions. Most of these lesions had multiple points of origin through the nasal, maxillary, and ethmoidal mucosa; the excellent visualization enabled direct cauterization of all these points of origin. The mean follow-up period was 7.96 years, and all patients were disease-free by the time the study was prepared. This article presents details of the treatment protocol and technique followed at our center for the treatment of nasopharyngeal rhinosporidiosis and the details of long-term follow-up. Through this study we hope to prove the efficacy of Le Fort I osteotomy in the definitive management of nasopharyngeal rhinosporidiosis.

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