scholarly journals Determining potential drug-drug interactions between lopinavir/ritonavir and other antiretrovirals and prescribed daily doses in a section of the private health care sector in South Africa

2013 ◽  
Vol 7 (41) ◽  
pp. 2727-2733
Author(s):  
L. Katende-Kyenda
Keyword(s):  
South Africa ◽  
Health Care ◽  
Drug Interactions ◽  
Health Care Sector ◽  
Potential Drug ◽  
Private Health Care

scholarly journals Are antiretrovirals prescribed according to the recommended prescribed daily doses in the private healthcare sector in South Africa

2011 ◽  
Vol 16 (1) ◽  
Author(s):  
Norah L. Katende-Kyenda ◽  
Martie Lubbe ◽  
Juan H.P. Serfontein ◽  
Ilse Truter
Keyword(s):  
South Africa ◽  
Health Care ◽  
Health Care Providers ◽  
Health Care Professionals ◽  
Health Care Sector ◽  
Hiv And Aids ◽  
Healthcare Sector ◽  
Private Health Care ◽  
Care Providers ◽  
Increased Risk

Current antiretroviral treatment (ART) guidelines recommend different combinations that have led to major improvements in the management of HIV and AIDS in the developed and developing world. With the rapid approval of many agents, health care providers may not be able to familiarise themselves with them all. This lack of knowledge leads to increased risk of dose- prescribing errors, especially by non-HIV and AIDS specialists. The purpose of this retrospective non-experimental, quantitative drug utilisation study was to evaluate if antiretrovirals (ARVs) are prescribed according to the recommended prescribed daily doses (PDDs) in a section of the private health care sector in South Africa (SA). Analysed ARV prescriptions (49995, 81096 and 88988) for HIV and AIDS patients were claimed from a national medicine claims database for the period 1 January 2005 through to 31 December 2007. ARV prescriptions prescribed by general practitioners (GPs) with PDDs not according to the recommended ARV dosing increased dramatically, from 12.33% in 2005 to 24.26% in 2007. Those prescribed by specialists (SPs) increased from 15.46% in 2005 to 35.20% in 2006 and decreased to 33.16% in 2007. The highest percentage of ARV prescriptions with PDDs not according to recommended ARV dosing guidelines was identified in ARV regimens with lopinavir−ritonavir at a PDD of 1066.4/264 mg and efavirenz at a PDD of 600 mg prescribed to patients in the age group of Group 3 (19 years > age ≤ 45 years). These regimens were mostly prescribed by GPs rather than SPs. There is a need for more education for all health care professionals and/or providers in the private health care sector in SA on recommended ARV doses, to avoid treatment failures, development of resistance, drug-related adverse effects and drug interactions.OpsommingHuidige riglyne vir behandeling met antiretrovirale middels beveel verskillende kombinasies aan wat tot groot verbetering in die beheer van MIV en VIGS in die ontwikkelde en ontwikkelende wêreld gelei het. Met die vinnige goedkeuring van talle nuwe middels kan dit gebeur dat verskaffers van gesondheidsorg nie kan bybly om hulle hiermee op hoogte te hou nie. Hierdie gebrek aan kennis lei tot ‘n hoër risiko vir foute in die voorgeskrewe dosis en veral deur persone wat nie spesialiste in MIV en VIGS is nie. Die doel van hierdie nie-eksperimentele, retrospektiewe, kwantitatiewe studie van die gebruik van geneesmiddels was om te bepaal of antiretrovirale middels in ‘n deel van die privaat gesondheidsorgsektor in Suid-Afrika (SA) volgens die aanbevole voorgeskrewe daaglikse dosisse (VDD) voorgeskryf word. Voorskrifte van antiretrovirale middels (49995, 81096 en 88988) aan pasiënte met MIV en VIGS wat in die periode van 1 Januarie 2005 tot 31 Desember 2007 van ‘n nasionale medisyne databasis geëis is, is ontleed. Voorskrifte van antiretrovirale middels deur algemene praktisyns (APs) met VDDs wat nie volgens die aanbevole dosisse vir antiretrovirale middels was nie, het dramaties van 12.33% in 2005 tot 24.26% in 2007 toegeneem. Die wat deur spesialiste (SPs) voorgeskryf is, het van 15.46% in 2005 tot 35.20% in 2006 toegeneem en in 2007 tot 33.16% gedaal. Die hoogste persentasie van voorskrifte vir antiretrovirale middels met VDDs wat nie volgens die riglyne was nie, was in die regimens met lopinavir−ritonavir met ‘n VDD van 1066.4/264 mg en efavirens met ‘n VDD van 600 mg wat aan pasiënte in die ouderdomsgroep van ouer as 19 tot en met 45 jaar voorgeskryf is. Hierdie regimens is meer deur APs as deur SPs voorgeskryf. Daar is ‘n behoefte aan nog opleiding van alle gesondheidsprofessies en/of voersieners in die privaat gesondheidsorgsektor in SA oor die aanbevole antiretrovirale middel-dosisse om mislukking van behandeling, ontwikkeling van weerstand, nadelige effekte vanweë geneesmiddels en geneesmiddel interaksies te voorkom.

scholarly journals Prescribing patterns of antiretroviral drugs in a section of the private health care sector of South Africa

2006 ◽  
Vol 11 (4) ◽  
Author(s):  
Danie Scholtz ◽  
Martie S Lubbe ◽  
Jan HP Serfontein ◽  
Dorcas Rakumakoe ◽  
Ronel Smit
Keyword(s):  
South Africa ◽  
Health Care ◽  
Full Text ◽  
Antiretroviral Drugs ◽  
Health Care Sector ◽  
Prescribing Patterns ◽  
Private Health Care ◽  
Claims Database

The general objective of this study was to investigate the prescribing patterns and cost of antiretroviral (ARV) drugs in the private health care sector in South Africa by using a medicine claims database. Opsomming Die doel van hierdie studie was om die voorskryfpatrone en medisynekoste van antiretrovirale (ARV) geneesmiddels in die private gesondheidsorgsektor in Suid-Afrika te ondersoek. *Please note: This is a reduced version of the abstract. Please refer to PDF for full text.

scholarly journals PND33 REFILL-ADHERENCE RATES OF ANTIPARKINSON MEDICATION IN THE PRIVATE HEALTH CARE SECTOR OF SOUTH AFRICA

2010 ◽  
Vol 13 (7) ◽  
pp. A394
Author(s):  
S Van der Merwe ◽  
MS Lubbe ◽  
JM Du Plessis ◽  
E Bekker
Keyword(s):  
South Africa ◽  
Health Care ◽  
Health Care Sector ◽  
Private Health Care ◽  
Refill Adherence

scholarly journals The potential market demand for biokinetics in the private health care sector of South Africa

2011 ◽  
Vol 23 (1) ◽  
pp. 14 ◽  
Author(s):  
SJ Moss ◽  
MS Lubbe
Keyword(s):  
South Africa ◽  
Health Care ◽  
Chronic Diseases ◽  
Health Professions ◽  
Health Care Sector ◽  
Market Potential ◽  
Market Demand ◽  
Private Health Care ◽  
Potential Market ◽  
Number Of Patients

Objective: Biokinetics, a profession registered with the Health Professions Council of South Africa (HPCSA), address inter alia chronic diseases of lifestyle (CDL) with exercise as treatment modality. The purpose of this investigation is to determine the potential market demand for biokinetic services in the private health care sector of South Africa. Methods: Data from a pharmaceutical benefit management system (PBM) were analysed to determine the prevalence of chronic diseases in the private health care sector for 2007. Telephonic interviews on a sub-sample of 50 biokineticists revealed the average number of patients that can be treated monthly per biokineticist. The number of biokineticists with active practice numbers was obtained from the Board of Health Care Funders (BHF). Results: The results indicate that 47% (747 199/1 600 000) of the patients managed by the PBM are treated with medication for one or more CDL. Non-steroid anti-inflammatory medication (21%), medication for cardiovascular diseases (13%) and bronchodilators (11%) had the highest prevalence. The sub-sample of biokineticists indicated that one biokineticist can treat an average of 100 patients per month. The potential market demand calculated from the above numbers indicated that 7 472 biokineticists are needed in the private health care sector, while only 625 active practice numbers were registered with the BHF in 2007.Conclusion: In conclusion, it is estimated that only 7.6% of patients with CDL can potentially be treated by the current number of registered biokineticists. Therefore an enormous market potential for biokinetics exists in the private health care sector of South Africa.

scholarly journals Early detection of infant hearing loss in the private health care sector of South Africa

2012 ◽  
Vol 76 (5) ◽  
pp. 698-703 ◽  
Author(s):  
Miriam Elsa Meyer ◽  
De Wet Swanepoel ◽  
Talita le Roux ◽  
Mike van der Linde
Keyword(s):  
South Africa ◽  
Health Care ◽  
Hearing Loss ◽  
Early Detection ◽  
Health Care Sector ◽  
Private Health Care

scholarly journals Investigation into the prescribing patterns and cost of antidiabetic medicine in South Africa

2007 ◽  
Vol 12 (3) ◽  
Author(s):  
Rianda Steyn ◽  
Johanita R Burger ◽  
Jan HP Serfontein ◽  
Martie S Lubbe
Keyword(s):  
South Africa ◽  
Health Care ◽  
Full Text ◽  
Health Care Sector ◽  
Prescribing Patterns ◽  
Private Health Care ◽  
Claims Database

The general objective of this study was to investigate the prescribing patterns and cost of antidiabetic medicine in the private health care sector in South Africa by using a medicine claims database. Opsomming Die algemene doelstelling van hierdie studie was om die voorskryfpatrone en koste van antidiabetiese medisyne in die private gesondheidsorgsektor van Suid-Afrika te ondersoek. *Please note: This is a reduced version of the abstract. Please refer to PDF for full text.

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