scholarly journals Metastatic disease of melanoma malignum choroid

2020 ◽  
Vol 25 (79) ◽  
pp. 55-63
Author(s):  
Snežana Knežević ◽  
Biljana Srećković ◽  
Jelena Vulović
Keyword(s):  
Case Report ◽  
Metastatic Disease ◽  
Skin Color ◽  
Choroidal Melanoma ◽  
Genetic Mutation ◽  
Medical Documentation ◽  
Primary Malignancy ◽  
Long Time ◽  
Melanoma Malignum ◽  
The Right

Introduction. Choroidal melanoma is a rare form of cancer, with a total of 3-5% of the patients suffering from this type of disease. People who are more likely to suffer from the disease are of the white race, bright skin color and iris, as well as those with a genetic mutation BAP 1 and GNAQ. Studies indicate the micro-metastatic disease before the primary process is diagnosed. There is no effective therapy to prevent the development of metastases. In 90% of cases the metastases are in the liver. Metastases can occur any time after the diagnosis of melanoma, even after 40 years. The prognosis of metastatic disease is bad, the median of survival per year is 4 to 15 months. Case report. The patient had enucleation of the eye, when he was primarily treated for malignant melanoma of choroid in 2007. He also appeared regularly for checkups. Felt healthy. 9 years later, dizziness and instability occurred. After a seizure, on July 2016, echotomography and computed tomography diagnosed liver, brain metastases as well as changes in the right lung. Radio-oncology treatment deposits in the brain done with Gama knife, as well as systemic hemotherapy with Dacarbazine. Changes in the lung treated as a secondary deposit. Despite oncology and palliative treatment, the patient passed away 6 months after the diagnosis of the metastatic disease. Conclusion. It is important to point out the importance of early and accurate diagnosis and early treatment of malignant diseases. During the period of monitoring the patient, rare localizations of the metastases must be considered, as well as the possibility of their occurrence long time after the discovery of the primary malignancy. For this case report, the data obtained from extensive medical documentation was used, as well as several years of monitoring patients in Primary care.

scholarly journals Yttrium-90 Radioembolization of Metastatic Adrenocortical Carcinoma to the Liver following Systemic Chemotherapy and Surgical Resection of the Primary Lesion

2020 ◽  
Vol 13 (1) ◽  
pp. 158-163
Author(s):  
Nicholas Pigg ◽  
Daniel Aboubechara ◽  
Roberto Fourzali ◽  
Brian Baigorri
Keyword(s):  
Case Report ◽  
Metastatic Disease ◽  
Adrenocortical Carcinoma ◽  
Liver Tumors ◽  
Primary Liver Tumors ◽  
Off Label ◽  
Metastatic Lesions ◽  
Potential Efficacy ◽  
The Right ◽  
Yttrium 90

Use of yttrium-90 (Y-90) is used for primary liver tumors and a handful of liver metastatic lesions. Y-90 treatment for metastatic adrenocortical carcinoma (ACC) to the liver is currently off-label, with one previously documented case report. In this case report, we present a 52-year-old woman with ACC and extensive liver metastatic disease. After failed chemotherapy, multidisciplinary discussion suggested potential Y-90 treatment for palliative purposes. After undergoing Y-90 treatment separately to the right and then the left hepatic lobes, subsequent patient visits demonstrated significantly improved clinical function as well as complete radiographic resolution of liver metastatic disease mainly from ACC. This case report demonstrates the potential efficacy of Y-90 for off-label uses in liver metastatic disease. This case and similar cases may open the door to a wide variety of potential indications for Y-90 treatment.

scholarly journals Scrofula Mimicking Cutaneous Malignancy: A Rare Case Report

2014 ◽  
Vol 6 (2) ◽  
pp. 68-70
Author(s):  
MK Garg ◽  
Uma Garg ◽  
Ritika Batra ◽  
Neha Salaria
Keyword(s):  
Case Report ◽  
Rare Case ◽  
Drug Susceptibility ◽  
Common Disease ◽  
Isolation And Identification ◽  
Cutaneous Malignancy ◽  
Rare Case Report ◽  
Long Time ◽  
The Right ◽  
Bacterium Tuberculosis

ABSTRACT Since a long time scrofuloderma (SCF) was thought to be a common disease of childhood and was attributable to Myco bacterium tuberculosis. In 1951, a new entity nontuberculous scrofuloderma was described and it is caused by atypical mycobacteria namely Mycobacterium scrofulaceum. The clinical picture closely mimics tuberculous scrofuloderma but diagnosis should be established through culture isolation and identification, because drug susceptibility may be different in these cases. In this article, we report a case of a 22-year-old pregnant female patient who presented to us with scrofulaceous lesion on the right side of neck. How to cite this article Garg U, Batra R, Salaria N, Garg MK. Scrofula Mimicking Cutaneous Malignancy: A Rare Case Report. Int J Otorhinolaryngol Clin 2014;6(2):68-70.

scholarly journals Perawatan Ameloblastoma Rekuren dengan Metode Dredging

2016 ◽  
Vol 19 (1) ◽  
pp. 160
Author(s):  
R. Rahardjo
Keyword(s):  
Case Report ◽  
Male Patient ◽  
Skin Color ◽  
Histopathological Examination ◽  
Recurrent Tumor ◽  
Facial Bones ◽  
The Common ◽  
Maxilla And Mandible ◽  
The Right ◽  
Progressive Enlargement

Latar belakang. Ameloblastoma dapat menyebabkan kerusakan pada tulang wajah baik pada maksila maupun mandibula. Tumor ini dapat mengalami rekurensi apabila perawatan tidak sempurna. Reseksi pada tulang yang terkena adalah tindakan yang biasa dilakukan untuk perawatan tumor ini. Tindakan ini dapat menyebabkan gangguan maloklusi, gangguan pertumbuhan dan perkembangan gigi dan tulang rahang bila dilakukan pada anak-anak dan remaja, gangguan estetika, dan berdampak psikologis. Oleh karena itu tindakan alternatif dalam perawatan ameloblastoma adalah dengan metode dredging. Tujuan laporan kasus ini menjelaskan perawatan metode dredging pada rekuren ameloblastoma pada penderita laki-laki usia dua puluh tujuh tahun sehingga dapat menghilangkan dampak psikologis dari penderita. Kasus. Penderita laki-laki usia dua puluh tujuah tahun dengan keluhan benjolan dalam mulut, tidak terasa sakit, dan merasa bertambah besar. Terdapat asimetri wajah di sebelah kanan, tidak ada perubahan warna kulit. Penderita mengaku pernah dioperasi tujuh tahun yang lalu. Pada pemeriksaan intra oral didapatkan benjolan pada mandibula di daerah bukal dari daerah gigi 42 sampai 46. Pada palpasi terasa ada fluktuasi, rasa sakit ringan dan warna mukosa normal. Pada gambaran foto panoramic terlihat area radiolusen dengan batas jelas dari daerah 42 sampai 46 dengan melibatkan aspek dari gigi 42 dan 43. Dari hasil biopsi dan pemeriksaan patologi anatomi dinyatakan sebagai ameloblastoma unikistik tipe folikuler. Penatalaksanaan. Dredging dikerjakan dengan melakukan defleksi pada lesi enukleasi dan kuretase. Pada bulan kedua perawatan tindakan tersebut diulangi dan dilakukan pemeriksaan histopatologis. Tindakan tersebut diulang pada bulan kelima dan diulang kembali setiap tiga bulan sampai dinyatakan terbebas dari sel tumor. Kesimpulan. Telah dilakukan dredging pada penderita rekuren ameloblastoma dengan hasil cukup memuaskan dan dilakukan pengamatan yang berlanjut. Background. Ameloblastoma can destruct the facial bones both the maxilla and mandible. The appearance of recurrent tumor is occured if the tumor is not totally removed. The resection of the affected bone is the common treatment of the tumor. These treatment lead complications such as malocclusion, abnormaldental and jaws development especially in children and adolescents, aesthetic problems, and psychological depressions. Therefore, the alternative treatment of it tumor is dredging method. Objection. This case report describe that dredging method treatment on recurrent ameloblastoma on male patient aged twenty seven years old, can eliminate patients’s psychological depressions. Case. Male patient aged twenty seven years old has a lump problem in mouth, painless, and has progressive enlargement, asymmetry on the right face, no change in skin color. Patients admitted to surgery seven years ago. On intra oral examination found a lump in the mandible in buccal area of the tooth 42 to 46. On palpation examination, there were fluctuations, mild pain and normal color mucosa. The panoramic photograph was found radiolucent area with clear boundaries of the region 42 to 46 by engaging aspect of teeth 42 and 43. The results of hispathology examination assessed a unicystic amelobastoma follicular type. Treatment. Dredging method was done by performing enucleation and consecutive curettage. Second month after the first treatment, the enucleation and the curettage was repeated then need histopathological examination. The treatment was repeated again in fifth month after the first treatment repeated every three months until histopathological examination declared free of tumor cells. Conclusion. Dredging has been performed on two patients with ameloblastoma with satisfactory results and continued observation.

scholarly journals Central incisor restoration (Case Report)

2021 ◽  
Vol 19 (1) ◽  
pp. 53-56
Author(s):  
Alessandro Conti
Keyword(s):  
Case Report ◽  
Minimal Invasive ◽  
Central Incisor ◽  
Long Time ◽  
The Right ◽  
Composite Restoration

This case report describes the 11 tooth old restoration removal and new direct composite restoration placement(Enamel Plus, Micerium S.p.A, Avengo, Ge, Italy). Direct anterior restorations are today a very nice, minimal invasive and cheap opportunity to restore one or more teeth. With the use of modern materials, the right techniques and protocols we can obtain mimetic restorations that they can work on the mouth of the patient for a long time.

Gastric carcinoma metastasis to the palatine tonsil – case report

2020 ◽  
Vol 9 (1) ◽  
pp. 50-53
Author(s):  
Dariusz Kaczmarczyk ◽  
Dawid Zagacki ◽  
Marcin Braun ◽  
Alina Morawiec-Sztandera
Keyword(s):  
Case Report ◽  
Gastric Carcinoma ◽  
Lymph Nodes ◽  
Metastatic Tumor ◽  
Palatine Tonsil ◽  
Medical Documentation ◽  
Histopathological Finding ◽  
Patient Reported ◽  
The Right ◽  
Pharyngeal Tonsil

<b>Aim:</b> The aim of the study is to present a rare case of metastatic tumor localized in pharyngeal tonsil being the first symptom of gastric carcinoma. <br><b>Case report:</b> Retrospective analysis of medical documentation was performed. A 44-years-old men was referred to the Department presenting a complaint of enlarged right pharyngeal tonsil. The mass was not painful. Patient reported tobacco smoking (20/day) for many years. In the intraoral examination a 2 cm right palatine tonsil was present. There was a slight asymmetry between tonsils. Local lymph nodes were not enlarged. FNAC was performed stating suspicion of carcinoma. Patient was qualified for the tonsillectomy under general anesthesia. Histopathological finding was adenocarcinoma (G2) infiltration. Due to no correlation of clinical presentation and histopathological finding PET-CT examination was performed revealing massive gastric infiltration, tumor of the left adrenal gland, increased 18-FDG uptake in epigastrial and para-aortic lymph nodes. Gastroscopy and biopsy was performed. Histopathological material confirmed adenocarcinoma presenting the same immunotype as tonsillar. Patient was qualified for paliative treatment. He died 6 weeks after stating the diagnosis. Metastases to the pharyngeal tonsils constitute rare disease entities. Mostly the primary site is localized in the region of head and neck. In our case the metastatic tumor of the right tonsil was the first sign of the gastric cancer.

Scrofula Mimicking Cutaneous Malignancy: A Rare Case Report

2015 ◽  
Vol 7 (1) ◽  
pp. 13-15
Author(s):  
MK Garg ◽  
Uma Garg ◽  
Ritika Batra ◽  
Neha Salaria
Keyword(s):  
Case Report ◽  
Rare Case ◽  
Drug Susceptibility ◽  
Common Disease ◽  
Isolation And Identification ◽  
Cutaneous Malignancy ◽  
Rare Case Report ◽  
Long Time ◽  
The Right ◽  
Bacterium Tuberculosis

ABSTRACT Since a long time scrofuloderma (SCF) was thought to be a common disease of childhood and was attributable to Myco_ bacterium tuberculosis. In 1951, a new entity nontuberculous scrofuloderma was described and it is caused by atypical mycobacteria namely Mycobacterium scrofulaceum. The clinical picture closely mimics tuberculous scrofuloderma but diagnosis should be established through culture isolation and identification, because drug susceptibility may be different in these cases. In this article, we report a case of a 22-year-old pregnant female patient who presented to us with scrofulaceous lesion on the right side of neck.

scholarly journals A Case Report of Lipoid Proteinosis with Brain and Laryngeal Presentation

2020 ◽  
Vol 17 (3) ◽  
Author(s):  
Mohammad Ali Kazemi ◽  
Zahra Ahmadian Mazhin ◽  
Hashem Sharifian ◽  
Samira Hemmati ◽  
Behnaz Moradi
Keyword(s):  
Case Report ◽  
Periodic Acid ◽  
Clinical Manifestations ◽  
Genetic Mutation ◽  
Imaging Findings ◽  
True Vocal Cord ◽  
Periodic Acid Schiff ◽  
Lipoid Proteinosis ◽  
Voice Changes ◽  
The Right

: Lipoid proteinosis (LP) is a rare autosomal recessive genodermatosis. Genetic mutation leads to deposition of abnormal amounts of hyaline like material in the skin and viscera, which is the cause of clinical manifestations. It mostly involves the skin, intracranium, and the larynx. In this case report, we present a case with a long history of hoarseness. Imaging findings include bilateral true vocal cord (TVC) mucosal irregularity with hyperdense depositions, bilateral medial temporal amygdala parallel bean shape calcification (pathognomonic sign), and bilateral striatal (caudate and putamen) hypoattenuation. The patient also had multiple warty papules on the hands. Biopsy of the right TVC showed submucosal deposition of periodic acid-Schiff (PAS)-positive amorphous hyaline material and confirmed the diagnosis of lipoid proteinosis. Typical imaging findings especially in the brain could be very helpful in interpretation of laryngeal imaging findings in cases of lipoid proteinosis who manifest with long term voice changes and hoarseness.

Breast Adenocarcinoma Mimicking Temporomandibular Disorders: A Case Report

2008 ◽  
Vol 9 (5) ◽  
pp. 100-106 ◽  
Author(s):  
Alynne Vieira de Menezes ◽  
Mariela Perira Lima ◽  
João Esmeraldo de Frota Mendonça ◽  
Francisco Haiter-Neto ◽  
Lucio Mitsuo Kurita
Keyword(s):  
Case Report ◽  
Temporomandibular Disorders ◽  
Temporomandibular Disorder ◽  
Metastatic Lesion ◽  
The Body ◽  
Breast Adenocarcinoma ◽  
Term Therapy ◽  
Primary Malignancy ◽  
The Right ◽  
Oral Metastasis

Abstract Aim The aim of this report is to present a case of a metastatic lesion in the mandible originating from a breast adenocarcinoma that was initially diagnosed as temporomandibular disorder (TMD). The role of the dental practitioner in the diagnostic phases is also discussed. Background It is not uncommon to see a patient who complains of what seems to be a TMD but who in reality suffers from a systematic disease, dental infection, or neoplasia. Although metastases to the head and neck are uncommon, it should always be considered among the differential diagnoses of lesions. Report A 42-year-old female presented with pain and swelling in the right temporomandibular joint (TMJ) previously diagnosed as TMD. Further clinical, radiological, and histological examinations coupled with a history of adenocarcinoma of the breast lead to a final diagnosis of a metastatic lesion in the right TMJ region. Summary In most patients who present with an oral metastasis the distant primary tumor has already been diagnosed and treated. Occasionally the discovery of an oral metastasis leads to the detection of an occult primary malignancy elsewhere in the body. Thus the dentist should be able to perform an adequate diagnosis and play an important role in the diagnostic phase of care that can lead to a useful palliation and an enhanced quality of the patient's life. Clinical Significance In order to avoid the pitfalls so common in evaluating patients with TMJ pain, the clinician must perform a complete and critical review of the medical history along with a comprehensive examination. The challenge is to know and evaluate the differential diagnosis. Failure to do so can result in a misdiagnosis which may lead to unnecessary care, long-term therapy without clinical resolution, or potentionally death. Citation Menezes AV, Lima MP, Mendonça JEdeF, Haiter-Neto F, Kurita LM. Breast Adenocarcinoma Mimicking Temporomandibular Disorders: A Case Report. J Contemp Dent Pract 2008 July; (9)5:100-106.

scholarly journals Huntington's Disease with Retinitis Pigmentosa- a Case Report

2017 ◽  
Vol 12 (1) ◽  
pp. 50-52
Author(s):  
Reaz Mahmud ◽  
Mansur Habib
Keyword(s):  
Case Report ◽  
Retinitis Pigmentosa ◽  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Autosomal Dominant ◽  
Neurodegenerative Disorder ◽  
Genetic Mutation ◽  
Medical Documentation ◽  
Dominant Inheritance ◽  
Nucleotide Triplet

Huntington's disease (HD) is a chronic neurodegenerative disorder, characterized by the following triad of clinical hallmarks: autosomal dominant inheritance, choreoathetosis, and dementia. In 1993 the genetic mutation responsible for HD was identified and mapped on the chromosome 4p16.3. The mutation is a characteristic expansion of a CAG nucleotide triplet. In this paper we present a 36-years-old male patient with HD. Additionally he also had retinitis pigmentosa. His pedigree was reconstructed using available medical documentation and tracing other members of his family.Faridpur Med. Coll. J. Jan 2017;12(1): 50-52

Sign in / Sign up

Export Citation Format

Share Document