A Study of Prefluid Disposable Syringe in Contrast Media Induced Adverse Reaction

1998 ◽  
Vol 54 (9) ◽  
pp. 1068

Adjacent tissues of considerably different density may be easily distinguished as a result of their natural contrast. However, adjacent soft tissues, such as a coronary artery and the blood within its lumen, have similar densities and are difficult to distinguish by natural contrast alone. In order to assess these tissue components individually, artificial contrast must be created between them. In X-ray CT, this is achieved using iodinated contrast agents. This chapter covers the chemistry, properties, administration, and practical guidelines of intravenous contrast media used in cardiovascular CT. It also highlights potential adverse reaction, and gives instructions on how to deal with them.


1989 ◽  
Vol 2 (3) ◽  
pp. 162-170 ◽  
Author(s):  
Dennis P. Swanson ◽  
Raymond W. Jurgens

Radiopaque contrast media (ROCM) are diagnostic drugs used for the enhancement of radiographic (x-ray) examinations. Although these agents have been used extensively for several years, pharmacist involvement with this category of drugs, to date, has been minimal. This article outlines several aspects of contrast media use in which pharmacists can or should become actively involved. Included in this discussion are possible roles of the pharmacist in decisions regarding respective product efficacy and use; adverse reaction prevention, reporting, monitoring, and treatment; and the evaluation of potential contrast media-drug or contrast media-laboratory test interactions. Pharmacist involvement associated with the use of traditional drugs in the performance of radiographic examinations and with technological advancements in radiology are also addressed. The overall magnitude of drug activity encountered in a radiology department suggests a needed and important role for pharmacists interested in this area.


1998 ◽  
Vol 39 (5) ◽  
pp. 576-578 ◽  
Author(s):  
J. M. Murphy ◽  
N. J. O'hare ◽  
P. Smiddy ◽  
M. P. Molloy

Gadopentetate dimeglumine (Gd-DTPA) is widely used as a contrast agent in MR imaging. We report on a case in which Gd-DTPA was used as the contrast agent during angioplasty in a patient who had recently had an adverse reaction to a non-ionic iodinated contrast medium. Gd-DTPA allowed a diagnostic angiogram to be performed with no side effects, and may thus be a useful contrast agent at angioplasty in patients with contra-indications to iodinated contrast media


2018 ◽  
Vol 2018 ◽  
pp. 1-5
Author(s):  
Félix Trottier-Tellier ◽  
Laurence Harvey ◽  
Jean-Daniel Baillargeon

Background and Aims.Few cases of endoscopic retrograde cholangiopancreatography- (ERCP-) related contrast media (CM) adverse reactions have been reported in the current literature. There is a lack of standardisation in practice regarding premedication prophylaxis for at-risk patients undergoing ERCP and there are few data to guide the practitioners. Our goal is to evaluate the risk of CM adverse reaction in a group of patients with a past history of allergic-like reaction to iodine product undergoing ERCP.Methods.A retrospective chart review study was performed of patients who underwent ERCP at our single centre from January 2010 to December 2015.Results.2295 ERCPs were performed among 1766 patients. No anaphylactoid or severe adverse reaction occurred. One (0.04%) ERCP-related CM benign reaction was reported in a patient known for penicillin allergy. Among 127 ERCPs performed on patients with a prior adverse reaction to iodine, 121 procedures were done without and 6 with a premedication prophylaxis. In both groups, no ERCP-related CM reaction occurred.Conclusions.To our knowledge, we report the largest cohort of iodine allergic patients undergoing ERCP ever published. These results suggest that ERCP-related CM adverse reactions are very rare even among patients at risk for CM reaction.


2019 ◽  
Vol 2 (1) ◽  
pp. 10-14
Author(s):  
Yulikha Ikhmawati ◽  
Zuhrial Zubir ◽  
Elvita Rahmi Daulay

The adverse reaction (AR) to intravenous contrast media (ICM) are relatively common. Various opinions pro-posed in the mechanism of the incidence of ICM AR. Suspected that the role of Immunoglobulin E (IgE) me-diates allergic conditions that are part of the AR. Objective:To determine the difference in total serum IgE level  among subjects with and without ICM AR on computed tomography (CT) scan examination. To ob-serve difference in total serum IgE levels in subjects undergoing ICM adverse reaction based on the degree of severity. Method: An analytical study with cross-sectional design of 104 subjects undergoing CT scans with ICM, examined IgE levels before and after ICM was administered, then measured the severity of adverse  re-actions of contrast media. Result: In this study, subjects undergoing adverse reactions, prior to administration Iopamidol  had a higher mean IgE 1270.79 mg / dl compared with those who having AR  1174.90 mg / dl and after administration of Iopamidol  a mean of Ig E is still higher in subjects having AR  1507.96 mg/dl com-pared with those having negative AR that is 1325.88 mg/dl, p = 0.696, statistically, not significant. Mild reac-tions in 40 subjects (38.5%) with cough, nausea, dizziness, itching, and sweating. Conclusion: Increase in total IgE levels in subjects with positive adverse reactions are independent(p=0.696).


2018 ◽  
Vol 60 (4) ◽  
pp. 496-500
Author(s):  
Joris Hrycyk ◽  
Johannes T Heverhagen ◽  
Ingrid Boehm

In addition to anaphylactic reactions induced by contrast media (CM), extravasation is an adverse reaction that occurs immediately, requires special treatment, and attention. Since radiologists are often not familiar with either prophylactic or treatment modalities, the goal of this paper is to summarize the major facts and recommendations with respect to CM extravasation under practical clinical aspects.


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