scholarly journals Role of P57KIP2 Immunohistochemical Expression in Histological Diagnosis of Hydatidiform Moles

2016 ◽  
Vol 17 (4) ◽  
pp. 2061-2066 ◽  
Author(s):  
Surang Triratanachat ◽  
Pattawan Nakaporntham ◽  
Patou Tantbirojn ◽  
Shanop Shuangshoti ◽  
Ruangsak Lertkhachonsuk
Keyword(s):  
Histological Diagnosis ◽  
Immunohistochemical Expression ◽  
Hydatidiform Moles

scholarly journals Thrombosis in essential thrombocytemia and early/prefibrotic primary myelofibrosis: the role of the WHO histological diagnosis

2015 ◽  
Vol 10 (1) ◽  
Author(s):  
Serena Rupoli ◽  
Gaia Goteri ◽  
Paola Picardi ◽  
Giorgia Micucci ◽  
Lucia Canafoglia ◽  
...  
Keyword(s):  
Primary Myelofibrosis ◽  
Histological Diagnosis ◽  
Essential Thrombocytemia

scholarly journals The Role of Endoscopic Ultrasound in the Diagnosis of Gallbladder Lesions

Diagnostics ◽  
2021 ◽  
Vol 11 (10) ◽  
pp. 1789
Author(s):  
Senju Hashimoto ◽  
Kazunori Nakaoka ◽  
Naoto Kawabe ◽  
Teiji Kuzuya ◽  
Kohei Funasaka ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
High Resolution ◽  
Endoscopic Ultrasound ◽  
Wall Thickness ◽  
Fine Needle Aspiration ◽  
Needle Aspiration ◽  
Histological Diagnosis ◽  
Fine Needle ◽  
High Resolution Images

Gallbladder (GB) diseases represent various lesions including gallstones, cholesterol polyps, adenomyomatosis, and GB carcinoma. This review aims to summarize the role of endoscopic ultrasound (EUS) in the diagnosis of GB lesions. EUS provides high-resolution images that can improve the diagnosis of GB polypoid lesions, GB wall thickness, and GB carcinoma staging. Contrast-enhancing agents may be useful for the differential diagnosis of GB lesions, but the evidence of their effectiveness is still limited. Thus, further studies are required in this area to establish its usefulness. EUS combined with fine-needle aspiration has played an increasing role in providing a histological diagnosis of GB tumors in addition to GB wall thickness.

scholarly journals The prognostic role of p-53 protein Immunohistochemical expression in multiple myeloma

2014 ◽  
Vol 56 (4) ◽  
pp. 385-389
Author(s):  
Muna A. Abdullah ◽  
◽  
Abdulkareem M. Jaafar ◽  
Adel R. ALsaadawi ◽  
◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Immunohistochemical Expression ◽  
Prognostic Role ◽  
P 53

scholarly journals Role of CD10 Immunohistochemical Expression in Predicting Aggressive Behavior of Phylloides Tumors

2015 ◽  
Vol 16 (8) ◽  
pp. 3147-3152 ◽  
Author(s):  
Muhammad Usman Tariq ◽  
Saroona Haroon ◽  
Naila Kayani
Keyword(s):  
Aggressive Behavior ◽  
Immunohistochemical Expression

Evaluation of immunohistochemical expression of mismatch repair proteins in endometrioid and seromucinous borderline ovarian tumors a 10-year experience in a large health care institution.

2021 ◽  
Vol 39 (15_suppl) ◽  
pp. e17557-e17557
Author(s):  
Hector Chavarria ◽  
Marina Frimer ◽  
Noah D. Kauff ◽  
Veena S. John ◽  
Seema Khutti
Keyword(s):  
Mismatch Repair ◽  
Ovarian Tumors ◽  
Borderline Tumor ◽  
Nuclear Staining ◽  
Immunohistochemical Expression ◽  
Stromal Invasion ◽  
Borderline Tumors ◽  
Dna Mismatch ◽  
Mismatch Repair Proteins

e17557 Background: Borderline tumors (BT) are atypical proliferation of epithelium in the ovary in the absence of destructive stromal invasion, representing for 15% of all epithelial ovarian cancers. [1] Around 10% of the ovarian tumors are hereditary, and approximately 10% of all the hereditary forms of epithelial ovarian tumors are result of a loss of DNA mismatch repair (MMR). [2] Endometrioid borderline tumor (EBT) and Seromucinous borderline tumors (SMBT) are rare tumors in ovary and there is limited literature available on immunohistochemical (IHC) expression of Mismatch repair proteins(MMRP)in these tumors.[3, 4] The aim of this study is to evaluate IHC expression of MMRP in EBT and SMBT of ovary. Methods: Pathology database was searched for ovarian Endometrioid borderline tumor (EBT) and Seromucinous borderline tumor (SMBT) for a 10-year period (2010-2020). The cohort consisted of 10 EBT (6 of which had focal microinvasion or carcinoma) and 12 SMBT(2 of which had focal carcinoma ). For comparison, 1 borderline Brenner. 15 serous borderline tumors (SBT) and 15 mucinous borderline tumors (MBT) were also included. After reviewing slides, a block with adequate borderline tumor was selected for IHC stains. For the cases with carcinoma, two different blocks with each component were selected. In all selected blocks, IHC stains for four MMRP (MLH1, PMS2, MSH2, MSH6) were performed. The complete absence of nuclear staining in tumor cells was considered as “loss” of the MMRP expression. Any “weak” or “focal” nuclear staining was considered intact. Results: Total 53 cases were evaluated for MMRP IHC. All cases had intact MMRP expression. In cases with carcinoma, both components (BT and carcinoma) have intact MMR IHC expression. See table. Conclusions: Our study did not show loss of MMRP IHC expression in EMT or SMBT. However, our study consisted of a small number of cases. Multi Institutional study with a large number of cases can be helpful in future to further evaluate the role of MMRP IHC in EMT and SMBT. [Table: see text]

The role of deoxyribonucleic acid image cytometric and interphase cytogenetic analyses in the differential diagnosis, prognosis, and clinical follow-up of hydatidiform moles

1997 ◽  
Vol 177 (5) ◽  
pp. 1219-1229 ◽  
Author(s):  
Christina A. van de Kaa ◽  
Charles P.T. Schijf ◽  
Peter C.M. de Wilde ◽  
Antonius G.J.M. Hanselaar ◽  
Peter G. Vooijs
Keyword(s):  
Differential Diagnosis ◽  
Deoxyribonucleic Acid ◽  
Cytogenetic Analyses ◽  
Hydatidiform Moles
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