scholarly journals Prediction of Liver Volume from Liver Transplant Donor using Biometric Formula compared with Computed Topography Volumetry

2021 ◽  
Vol 6 (1) ◽  
Keyword(s):  
Liver Transplant ◽  
Liver Volume ◽  
Computed Topography ◽  
Liver Transplant Donor

Reliable Estimation of Preoperative Graft Volume in Living Donor Liver Transplantation

2021 ◽  
Vol 15 (11) ◽  
pp. 3030-3033
Author(s):  
Amer Latif ◽  
M Akif Dilshad ◽  
Sumbul Naz ◽  
Sadia Jabbar ◽  
Faisal Naseer ◽  
...  
Keyword(s):  
Liver Transplant ◽  
Living Donor ◽  
Liver Volume ◽  
Volume Estimation ◽  
Accurate Estimation ◽  
Donor Liver ◽  
Living Donor Liver Transplant ◽  
Right Lobe ◽  
Graft Weight ◽  
Donor Liver Transplant

Aims & Objectives: Corner stone in performing living donor liver transplant is to assess and predict the adequacy of the donated liver for recipient and remaining liver. Previously the conversion of liver volume to estimated weight is done by using unit to unit conversion with a factor of 1. We analyzed data of our institute to research the methodology and local applicability of the same. Place and duration of study: Shaikh Zayed Hospital, Lahore. January 2011 to June 2017 Material & Methods: Retrospective data was collected for the first 115 recipients and donors. Their preoperative liver volumes calculated by C.T scan and post-operative graft harvested with weights were compared. Results: The parameter of actual volume of right lobe averaged to 769.77 ± 12.73 gm varying with a quantum of 17.73% (426 – 1123 gm). Estimated volume of right lobe of liver varied 358 to 1218 ml (CV = 17.84%) with an average value of 798.96 ± 13.29 ml. Results of linear regression between estimated volume of right lobe and actual weight of the right lobe in gm was significantly linear (r = 0.830, r2 = 0.690, adj. r2 = 0.689 and F = 250.98, p < 0.0001), showing that volumetric assessment overestimated graft weight/volume. Following is equation generated from our data for graft weight estimation. Actual right lobe (g) = 134.004 + 0.796 (estimated right lobe volume (ml) ± 76.42. Conclusion: Using one to one principle for volume estimation of healthy liver can be misleading and therefore we propose an equation to reach more accurate estimation of graft weight. Keywords: living donor liver transplant, CT volumetry, graft to body weight ratio

scholarly journals A case of coronavirus disease 2019–infected liver transplant donor

2020 ◽  
Vol 20 (10) ◽  
pp. 2938-2941 ◽  
Author(s):  
Hyo‐Lim Hong ◽  
Sung‐Han Kim ◽  
Dong Lak Choi ◽  
Hyun Hee Kwon
Keyword(s):  
Liver Transplant ◽  
Infected Liver ◽  
Liver Transplant Donor

The use of stereotactic body radiotherapy as a bridge to liver transplantation for hepatocellular carcinoma.

2016 ◽  
Vol 34 (4_suppl) ◽  
pp. 418-418 ◽  
Author(s):  
Aisling S Barry ◽  
Gonzalo Sapisochin ◽  
Moises Russo ◽  
Anthony M. Brade ◽  
James D. Brierley ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Transplant ◽  
Stereotactic Body Radiotherapy ◽  
Liver Volume ◽  
Disease Free Survival ◽  
Patient Characteristics ◽  
Median Number ◽  
Wait List ◽  
Bridging Therapy ◽  
Actuarial Survival

418 Background: Approximately 30% of patients with hepatocellular carcinoma (HCC) on the wait list for liver transplant (LT) fall off the transplant list due to progressive HCC. Stereotactic Body Radiotherapy (SBRT) has been used as a “bridge” to LT in patients who are not amenable to RFA or TACE. Methods: Baseline patient characteristics, radiotherapy details and outcomes were reviewed in HCC patients who received SBRT as a bridge to LT. Results: Between July 2004 and Dec. 2014, 601 patients with HCC were listed for LT, of which 400 (66.5%) received bridging therapy. 38 patients, at high risk for HCC progression, were unsuitable for RFA or TACE, receiving SBRT as a bridging therapy. Median SBRT dose was 36Gy in 6 fractions (range 8.5-48Gy in 1 – 6 fractions), including 1 patient who was transplanted after receiving one fraction. 25 of 38 patients (67%) had all lesions treated (median number of lesions 2 {1-8}); 13 patients received SBRT only to the dominant lesion at highest risk of growing or rupturing. At the time of SBRT, 42% had HCC within Milan criteria, and median Child Pugh score was A6 (range A5-B8). 5 patients (13%) dropped off the transplant wait list due to development of metastatic disease (4) and macrovascular invasion with progressive disease (1). Median irradiated HCC volume was 60.5cc (range 7-216cc). Median liver volume (minus HCC) was 1491cc (737-2728cc). Median mean dose to the liver minus HCC was 11.2Gy (2.8-18.6Gy) and median effective liver volume irradiated was 28% (11-66%). 1 patient was admitted 2 months post SBRT with hepatic pain - possibly attributable to SBRT and another patient developed a rib fracture 8 months post SBRT (max rib dose 43Gy in 6 fractions). No other specific SBRT toxicity was noted. The 1-, 3- and 5-year disease free survival and actuarial survival of HCC patients treated with SBRT who went on to have transplant was 93%, 79% and 79%, and 89%, 76% and 76% respectively. Including patients who dropped off the transplant list, the intent-to-treat 1-, 3 - and 5-year survival was 89%, 65% and 65%. There was no reported increase in operative morbidity at the time of transplant in patients treated with SBRT. Conclusions: SBRT can be used safely and effectively in HCC patients as a bridge to liver transplant.

scholarly journals Liver transplant donor candidates: Associations between vascular and biliary anatomic variants

2004 ◽  
Vol 10 (8) ◽  
pp. 1049-1054 ◽  
Author(s):  
Vivian S. Lee ◽  
Glyn R. Morgan ◽  
Jennifer C. Lin ◽  
Carol A. Nazzaro ◽  
Jerry S. Chang ◽  
...  
Keyword(s):  
Liver Transplant ◽  
Anatomic Variants ◽  
Liver Transplant Donor

Lignocaine Metabolism and MEGX Production in the Liver Transplant Donor

1992 ◽  
Vol 36 (6) ◽  
pp. 387
Author(s):  
J. M. POTTER ◽  
P. E. HICKMAN ◽  
G. BALDERSON ◽  
S. V. LYNCH ◽  
R. STRONG
Keyword(s):  
Liver Transplant ◽  
Liver Transplant Donor

scholarly journals CEACAM1 and molecular signaling pathways to expand the liver transplant donor pool

2020 ◽  
Vol 130 (5) ◽  
pp. 2192-2194 ◽  
Author(s):  
Samer Tohme ◽  
David A. Geller
Keyword(s):  
Liver Transplant ◽  
Signaling Pathways ◽  
Molecular Signaling ◽  
Donor Pool ◽  
Molecular Signaling Pathways ◽  
Liver Transplant Donor

Living Donor Liver Transplant: Donor Hepatectomy

2016 ◽  
pp. 112-112
Author(s):  
Naimish Mehta ◽  
Vinay Kumaran
Keyword(s):  
Liver Transplant ◽  
Living Donor ◽  
Donor Liver ◽  
Donor Hepatectomy ◽  
Living Donor Liver Transplant ◽  
Donor Liver Transplant ◽  
Liver Transplant Donor

Oil Red O-assessed macrosteatosis in liver transplant donor biopsies predicts ischemia–reperfusion injury and clinical outcome

2013 ◽  
Vol 464 (2) ◽  
pp. 165-174 ◽  
Author(s):  
Henning Reis ◽  
Patricia T. Peterek ◽  
Jeremias Wohlschlaeger ◽  
Gernot M. Kaiser ◽  
Zoltan Mathe ◽  
...  
Keyword(s):  
Clinical Outcome ◽  
Liver Transplant ◽  
Reperfusion Injury ◽  
Ischemia Reperfusion Injury ◽  
Ischemia Reperfusion ◽  
Liver Transplant Donor ◽  
Oil Red O

IN VIVO VALIDATION OF LIVER VOLUME DETERMINATION WITH TECHNETIUM-99M SULFUR COLLOID SPECT STUDIES: RESULTS IN LIVER TRANSPLANT RECIPIENTS

1989 ◽  
Vol 14 (Supplement) ◽  
pp. P17
Author(s):  
C Carlson ◽  
D Marciano ◽  
R W Busuttil ◽  
S Glickman ◽  
R A Hawkins
Keyword(s):  
Liver Transplant ◽  
Liver Volume ◽  
Transplant Recipients ◽  
Sulfur Colloid ◽  
Volume Determination ◽  
Technetium 99M ◽  
Liver Transplant Recipients ◽  
In Vivo Validation
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