scholarly journals Decision letter: Genome-wide mapping in a house mouse hybrid zone reveals hybrid sterility loci and Dobzhansky-Muller interactions

2014 ◽  
Keyword(s):  
House Mouse ◽  
Hybrid Zone ◽  
Hybrid Sterility ◽  
Genome Wide

scholarly journals Genome-wide mapping in a house mouse hybrid zone reveals hybrid sterility loci and Dobzhansky-Muller interactions

eLife ◽  
2014 ◽  
Vol 3 ◽  
Author(s):  
Leslie M Turner ◽  
Bettina Harr
Keyword(s):  
House Mouse ◽  
Hybrid Zone ◽  
Hybrid Sterility ◽  
Testis Weight ◽  
Hybrid Zones ◽  
Incipient Species ◽  
Complex Interactions ◽  
Genetic Mechanisms ◽  
Resolution Mapping ◽  
Genomic Regions

Mapping hybrid defects in contact zones between incipient species can identify genomic regions contributing to reproductive isolation and reveal genetic mechanisms of speciation. The house mouse features a rare combination of sophisticated genetic tools and natural hybrid zones between subspecies. Male hybrids often show reduced fertility, a common reproductive barrier between incipient species. Laboratory crosses have identified sterility loci, but each encompasses hundreds of genes. We map genetic determinants of testis weight and testis gene expression using offspring of mice captured in a hybrid zone between M. musculus musculus and M. m. domesticus. Many generations of admixture enables high-resolution mapping of loci contributing to these sterility-related phenotypes. We identify complex interactions among sterility loci, suggesting multiple, non-independent genetic incompatibilities contribute to barriers to gene flow in the hybrid zone.

scholarly journals Genome-Wide Mapping In A House Mouse Hybrid Zone Reveals Hybrid Sterility Loci And Dobzhansky-Muller Interactions

2014 ◽  
Author(s):  
Leslie Turner ◽  
Bettina Harr
Keyword(s):  
House Mouse ◽  
Hybrid Zone ◽  
Hybrid Sterility ◽  
Testis Weight ◽  
Hybrid Zones ◽  
Incipient Species ◽  
Complex Interactions ◽  
Genetic Mechanisms ◽  
Resolution Mapping ◽  
Genomic Regions

Mapping hybrid defects in contact zones between incipient species can identify genomic regions contributing to reproductive isolation and reveal genetic mechanisms of speciation. The house mouse features a rare combination of sophisticated genetic tools and natural hybrid zones between subspecies. Male hybrids often show reduced fertility, a common reproductive barrier between incipient species. Laboratory crosses have identified sterility loci, but each encompasses hundreds of genes. We map genetic determinants of testis weight and testis gene expression using offspring of mice captured in a hybrid zone between M. musculus musculus and M. m. domesticus. Many generations of admixture enables high-resolution mapping of loci contributing to these sterility-related phenotypes. We identify complex interactions among sterility loci, suggesting multiple, non-independent genetic incompatibilities contribute to barriers to gene flow in the hybrid zone.

scholarly journals Genome-wide patterns of gene flow across a house mouse hybrid zone

2007 ◽  
Vol 18 (1) ◽  
pp. 67-76 ◽  
Author(s):  
K. C. Teeter ◽  
B. A. Payseur ◽  
L. W. Harris ◽  
M. A. Bakewell ◽  
L. M. Thibodeau ◽  
...  
Keyword(s):  
Gene Flow ◽  
House Mouse ◽  
Hybrid Zone ◽  
Genome Wide

scholarly journals WHERE ARE THE WORMY MICE? A REEXAMINATION OF HYBRID PARASITISM IN THE EUROPEAN HOUSE MOUSE HYBRID ZONE

Evolution ◽  
2012 ◽  
Vol 66 (9) ◽  
pp. 2757-2772 ◽  
Author(s):  
Stuart J. E. Baird ◽  
Alexis Ribas ◽  
Miloš Macholán ◽  
Tomáš Albrecht ◽  
Jaroslav Piálek ◽  
...  
Keyword(s):  
House Mouse ◽  
Hybrid Zone

scholarly journals Testing parasite ‘intimacy’: the whipwormTrichuris murisin the European house mouse hybrid zone

2016 ◽  
Vol 6 (9) ◽  
pp. 2688-2701 ◽  
Author(s):  
  Wasimuddin ◽  
Josef Bryja ◽  
Alexis Ribas ◽  
Stuart J. E. Baird ◽  
Jaroslav Piálek ◽  
...  
Keyword(s):  
House Mouse ◽  
Hybrid Zone

Strong premating divergence in a unimodal hybrid zone between two subspecies of the house mouse

2003 ◽  
Vol 17 (1) ◽  
pp. 165-176 ◽  
Author(s):  
C. Smadja ◽  
J. Catalan ◽  
G. Ganem
Keyword(s):  
House Mouse ◽  
Hybrid Zone

scholarly journals REDUCED MALE FERTILITY IS COMMON BUT HIGHLY VARIABLE IN FORM AND SEVERITY IN A NATURAL HOUSE MOUSE HYBRID ZONE

Evolution ◽  
2011 ◽  
Vol 66 (2) ◽  
pp. 443-458 ◽  
Author(s):  
Leslie M. Turner ◽  
Denise J. Schwahn ◽  
Bettina Harr
Keyword(s):  
House Mouse ◽  
Hybrid Zone ◽  
Male Fertility
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