scholarly journals Response: Factors Predicting Weight Loss after “Sleeve Gastrectomy with Loop Duodenojejunal Bypass” Surgery for Obesity (J Obes Metab Syndr 2020;29:208-14)

2020 ◽  
Vol 29 (4) ◽  
pp. 327-329
Author(s):  
Amar Vennapusa ◽  
Ramakanth Bhargav Panchangam ◽  
Charita Kesara ◽  
Tejaswi Chivukula

2020 ◽  
Vol 29 (3) ◽  
pp. 208-214
Author(s):  
Amar Vennapusa ◽  
Ramakanth Bhargav Panchangam ◽  
Charita Kesara ◽  
Tejaswi Chivukula


2020 ◽  
Vol 9 (2) ◽  
pp. 33-41
Author(s):  
Amar Vennapusa ◽  
Ramakanth Bhargav Panchangam ◽  
Charita Kesara ◽  
Mukharjee SS Madivada


2016 ◽  
Vol 27 (3) ◽  
pp. 795-801 ◽  
Author(s):  
Yosuke Seki ◽  
Kazunori Kasama ◽  
Hidenori Haruta ◽  
Atsushi Watanabe ◽  
Renzo Yokoyama ◽  
...  


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Tim Hollstein ◽  
Kristina Schlicht ◽  
Laura Krause ◽  
Stefanie Hagen ◽  
Nathalie Rohmann ◽  
...  

AbstractObesity is associated with a “natriuretic handicap” indicated by reduced N-terminal fragment of proBNP (NT-proBNP) concentration. While gastric bypass surgery improves the natriuretic handicap, it is presently unclear if sleeve gastrectomy exhibits similar effects. We examined NT-proBNP serum concentration in n = 72 obese participants without heart failure before and 6 months after sleeve gastrectomy (n = 28), gastric bypass surgery (n = 19), and 3-month 800 kcal/day very-low calorie diet (n = 25). A significant weight loss was observed in all intervention groups. Within 6 months, NT-proBNP concentration tended to increase by a median of 44.3 pg/mL in the sleeve gastrectomy group (p = 0.07), while it remained unchanged in the other groups (all p ≥ 0.50). To gain insights into potential effectors, we additionally analyzed NT-proBNP serum concentration in n = 387 individuals with different metabolic phenotypes. Here, higher NT-proBNP levels were associated with lower nutritional fat and protein but not with carbohydrate intake. Of interest, NT-proBNP serum concentrations were inversely correlated with fasting glucose concentration in euglycemic individuals but not in individuals with prediabetes or type 2 diabetes. In conclusion, sleeve gastrectomy tended to increase NT-proBNP levels in obese individuals and might improve the obesity-associated “natriuretic handicap”. Thereby, nutritional fat and protein intake and the individual glucose homeostasis might be metabolic determinants of NT-proBNP serum concentration.



2018 ◽  
Author(s):  
Fernanda L. Paganelli ◽  
Misha Luyer ◽  
C. Marijn Hazelbag ◽  
Hae-Won Uh ◽  
Malbert R.C. Rogers ◽  
...  

AbstractBackgroundBariatric surgery in patients with morbid obesity, either through gastric sleeve gastrectomy or Roux-Y gastric bypass surgery, leads to sustainable weight loss, improvement of metabolic disorders and changes in the intestinal microbiota. Yet, the relationship between changes in gut microbiota, weight loss and the surgical procedure remains incompletely understood.Subjects/MethodsWe determined temporal changes in microbiota composition in 45 obese patients undergoing a crash diet followed by gastric sleeve gastrectomy (n= 22) or Roux-Y gastric bypass (n= 23). Intestinal microbiota composition was determined before intervention (baseline, S1), 2 weeks after a crash diet (S2), and 1 week (S3), 3 months (S4) and 6 months (S5) after surgery.ResultsRelative to S1, the microbial diversity index declined at S2 and S3 (p< 0.05), and gradually returned to baseline levels at S5. The crash diet was associated with an increased abundance of Rikenellaceae and decreased abundances of Ruminococcaceae and Streptococcaceae (p< 0.05). After surgery, at S3, the relative abundance of Bifidobacteriaceae had decreased (compared to the moment directly after the crash diet), whereas those of Streptococcaceae and Enterobacteriaceae had increased (p< 0.05). Increased weight loss during the next 6 months was not associated without major changes in microbiota composition. Significant differences between both surgical procedures were not observed at any of the time points.ConclusionsIn conclusion, undergoing a crash diet and bariatric surgery were associated with an immediate but temporary decline in the microbial diversity, with immediate and permanent changes in microbiota composition, with no differences between patients undergoing gastric sleeve gastrectomy or Roux-Y gastric bypass surgery.



2013 ◽  
Author(s):  
Chen Abel Weiliang ◽  
Ming Lee Samuel Shang ◽  
Lee Wei Feng ◽  
Yuan Cher Gabriel Liu ◽  
Seow Cherng Jye ◽  
...  




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