scholarly journals Acute Myocardial Infarction with Microthrombi in Cardiac Small Vessels after COVID-19 Vaccination (ChAdOx1 nCov-19): A Case Report

2021 ◽  
Vol 45 (4) ◽  
pp. 127-132
Author(s):  
Sohyung Park ◽  
Byung-Ha Choi
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Myocardial Injury ◽  
Pulmonary Arteries ◽  
Vena Cava ◽  
Left Ventricular ◽  
Unexpected Death ◽  
Small Vessels ◽  
Left Ventricular Rupture ◽  
The Brain

We present the postmortem findings of an unexpected death due to acute myocardial infarction (AMI) with microthrombi and thrombosis in other vessels after the first dose of coronavirus disease 2019 (COVID-19) vaccination (ChAdOx1 nCov-19). The deceased was a 69-year-old woman who complained of nonspecific symptoms shortly after vaccination and was found dead on the sixth day. Postmortem examination revealed AMI and complications (left ventricular rupture, hemopericardium) with microthrombi in small cardiac vessels, which are similar to the characteristic findings of myocardial injury caused by microthrombi in patients with COVID-19. Nonobstructive thromboembolism in the pulmonary arteries and inferior vena cava, and fibrin microthrombi in some small vessels in the brain were also observed. It is unclear whether these findings are associated with COVID-19 vaccination, and further comprehensive studies are needed.

scholarly journals Association between the osmotic fragility of erythrocytes and the course of acute myocardial infarction

2021 ◽  
Vol 10 (3) ◽  
pp. 6-14
Author(s):  
A. A. Garganeeva ◽  
V. A. Aleksandrenko ◽  
E. A. Kuzheleva ◽  
V. V. Ryabov ◽  
T. Yu. Rebrova ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Myocardial Contractility ◽  
Myocardial Injury ◽  
Creatine Phosphokinase ◽  
Troponin I ◽  
Osmotic Fragility ◽  
Myocardial Necrosis ◽  
Left Ventricular ◽  
Erythrocyte Osmotic Fragility

Aim.      To investigate the relationship between the osmotic fragility of erythrocytes and the course of acute myocardial infarction (MI).Methods.           An analysis of the osmotic fragility of erythrocytes was conducted using beta-blocker-based osmotic fragility test in sixty-two patients within the first 6 hours after onset of MI symptoms.Results. The results revealed that the patients with increased erythrocyte osmotic fragility experienced more complications after acute MI, such as left ventricular failure and cardiac arrhythmias (ventricular extrasystoles and ventricular tachycardia) (p = 0.026). Moreover, these patients exhibited greater myocardial injury - the concentration of biomarkers of myocardial necrosis, such as creatine phosphokinase, creatine phosphokinase MB and Troponin I was increased - p = 0.009, p = 0.032 and p = 0.001, respectively. In addition to that, the patients with high osmotic fragility had a larger number of hypokinetic and akinetic segments, high impaired myocardial contractility index, and low ejection fraction. The impaired myocardial contractility index was significantly higher in patients with increased erythrocyte osmotic fragility (1.5 (1.22; 1.75) vs 1.12 (1.0; 1.56), U = 157.5, p = 0.032).Conclusion. Increased erythrocyte osmotic fragility in patients was associated with greater myocardial injury, manifesting through the higher concentration of biomarkers of myocardial necrosis in blood, as well as higher number of hypokinetic segments.

scholarly journals SUCCESSFUL SURGICAL REPAIR OF LEFT VENTRICULAR RUPTURE AFTER ACUTE MYOCARDIAL INFARCTION

1984 ◽  
Vol 48 (11) ◽  
pp. 1215-1224 ◽  
Author(s):  
HARUO MIYAMURA ◽  
MASATOMO YAZAWA ◽  
YOSHIHIKO YAMAZAKI ◽  
KEN-ICHI TOGASHI ◽  
HAJIME OHZEKI ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Surgical Repair ◽  
Left Ventricular ◽  
Ventricular Rupture ◽  
Left Ventricular Rupture

Left ventricular rupture in an anterior wall acute myocardial infarction with severe intra-ventricular gradient

2011 ◽  
Vol 33 (2) ◽  
pp. 206-208
Author(s):  
Natale Daniele Brunetti ◽  
Riccardo Ieva ◽  
Michele Correale ◽  
Luigi Flavio Massimiliano Di Martino ◽  
Luisa De Gennaro ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Anterior Wall ◽  
Left Ventricular ◽  
Ventricular Rupture ◽  
Left Ventricular Rupture
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