Think superficial thrombophlebitis, because time might be of the essence

2021 ◽  
Vol 36 (11) ◽  
pp. 70-72
Author(s):  
Gill O’Brien
1980 ◽  
Vol 44 (02) ◽  
pp. 092-095 ◽  
Author(s):  
T H Tran ◽  
C Bondeli ◽  
G A Marbet ◽  
F Duckert

SummaryTwo different AT-III fractions were purified from the plasma of a patient with recurrent superficial thrombophlebitis. The abnormal AT-III fraction (A-AT) was compared to the normal AT-III fraction (N-AT) in the inhibition of thrombin and factor Xa. Without heparin, both inactivate proteases in a similar manner and at the same rate. However, at low heparin concentration the thrombin inhibition proceeds more slowly with A-AT than with N-AT. At high heparin concentration the difference between A-AT and N-AT becomes very small. The inhibition of factor Xa follows a similar pattern. It is suggested that the heparin binding site of A-AT differs from that of N-AT resulting in a decreased heparin cofactor activity.


2008 ◽  
Vol 6 (8) ◽  
pp. 760-765 ◽  
Author(s):  
Jason T. Lee ◽  
Maziyar A. Kalani

Superficial venous thrombophlebitis (SVT) is characterized as a localized inflammatory condition of the venous vessels underlying the skin. It arises from thrombosis of a superficial vein, and clinical presentation usually involves pain, erythema, and tenderness at the sites of inflammation. Although the condition is usually self-limited and not serious or fatal, symptomatic superficial thrombophlebitis can be debilitating, limit movement and certain capabilities, or progress to involve the deep venous system and cause pulmonary embolism. SVT is typically associated with venous valvular insufficiency, pregnancy, infection, and prothrombotic conditions, including malignancy. Currently, medical therapies comprising bedrest, elastic stockings, compression bandages, nonsteroidal anti-inflammatory drugs, and low molecular weight heparins are used to reduce the extension of inflammation and recurrence of thrombotic events in patients experiencing SVT. In patients refractory to conservative measures, surgical interventions such as phlebectomy, sclerotherapy, saphenous junction ligation, or saphenous vein stripping are potential treatments.


2010 ◽  
Vol 8 (1) ◽  
pp. 47-50 ◽  
Author(s):  
F. F. van Doormaal ◽  
S. Atalay ◽  
H. J. Brouwer ◽  
E.-F. van der Velde ◽  
H. R. Buller ◽  
...  

Angiology ◽  
1953 ◽  
Vol 4 (4) ◽  
pp. 374-379 ◽  
Author(s):  
R.B. Lynn

Author(s):  
Benjamin Jacobs ◽  
Dawn M. Coleman

2007 ◽  
Vol 26 (2) ◽  
pp. 71-76 ◽  
Author(s):  
José Luis Rodríguez-Peralto ◽  
Rosario Carrillo ◽  
Belén Rosales ◽  
Yolanda Rodríguez-Gil

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